| scholarly article | Q13442814 |
| P2093 | author name string | K. Georgopoulos | |
| T. Ikeda | |||
| J. H. Wang | |||
| C. Friedrich | |||
| B. A. Morgan | |||
| L. Liang | |||
| S. Pillai | |||
| A. Cariappa | |||
| A. Renold | |||
| K. Andrikopoulos | |||
| N. Avitahl | |||
| P2860 | cites work | Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation | Q24532162 |
| Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin | Q24605629 | ||
| The role of the Ikaros gene in lymphocyte development and homeostasis | Q28237613 | ||
| Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors | Q28268827 | ||
| Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice | Q28272701 | ||
| Cells in the marginal zone of the spleen | Q28294678 | ||
| Hyperresponsive B cells in CD22-deficient mice | Q28510573 | ||
| Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation | Q28584704 | ||
| The Ikaros gene is required for the development of all lymphoid lineages | Q28594316 | ||
| A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei | Q29616800 | ||
| Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences | Q33280888 | ||
| Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. | Q34308479 | ||
| Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation | Q34412659 | ||
| Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin | Q34450725 | ||
| Transcription factors and the control of DNA replication | Q35673472 | ||
| Mapping replicational sites in the eucaryotic cell nucleus | Q36219820 | ||
| Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow | Q36230070 | ||
| The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver | Q36362209 | ||
| Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells | Q36365247 | ||
| Involvement of B-1 cells in mucosal immunity and autoimmunity | Q40380357 | ||
| Distinctive developmental origins and specificities of murine CD5+ B cells | Q40390845 | ||
| Surrogate light chain in B cell development. | Q41096673 | ||
| The "clonal selection hypothesis" and current concepts of B cell tolerance | Q41113352 | ||
| Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication | Q41526613 | ||
| Replication factories | Q44126447 | ||
| Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. | Q46863693 | ||
| Germline transcripts of the murine immunoglobulin gamma 2a gene: structure and induction by IFN-gamma | Q48107272 | ||
| In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. | Q52192552 | ||
| CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. | Q52198671 | ||
| Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. | Q52201971 | ||
| Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex | Q57198357 | ||
| The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes | Q59098629 | ||
| A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma | Q71806450 | ||
| The role of Ig beta in precursor B cell transition and allelic exclusion | Q72155513 | ||
| The SHIP phosphatase becomes associated with Fc gammaRIIB1 and is tyrosine phosphorylated during 'negative' signaling | Q73115318 | ||
| Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation | Q73574914 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | IKAROS family zinc finger 3 | Q21984523 |
| P304 | page(s) | 543–553 | |
| P577 | publication date | 1998-10-01 | |
| P1433 | published in | Immunity | Q6005457 |
| P1476 | title | Aiolos regulates B cell activation and maturation to effector state | |
| P478 | volume | 9 |
| Q28217853 | A molecular dissection of the repression circuitry of Ikaros |
| Q37061440 | Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells. |
| Q39163794 | Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth |
| Q41692822 | Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity |
| Q40128287 | Aiolos controls gene conversion and cell death in DT40 B cells |
| Q42971089 | Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity |
| Q36520966 | Aiolos promotes TH17 differentiation by directly silencing Il2 expression |
| Q33806421 | Aiolos promotes anchorage independence by silencing p66Shc transcription in cancer cells |
| Q22009996 | Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization |
| Q35990654 | Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood |
| Q81461288 | Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival |
| Q34547252 | Antigen-dependent B-cell development |
| Q34278140 | Association between polymorphisms of the IKZF3 gene and systemic lupus erythematosus in a Chinese Han population |
| Q36161777 | Autoimmune glomerulonephritis with spontaneous formation of splenic germinal centers in mice lacking the estrogen receptor alpha gene |
| Q47239310 | Avian Helios and evolution of the Ikaros family |
| Q36884474 | Avian model for B-cell immunology--new genomes and phylotranscriptomics |
| Q90254570 | B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains |
| Q28304887 | B cell antigen receptor signal strength and peripheral B cell development are regulated by a 9-O-acetyl sialic acid esterase |
| Q41962946 | Blk haploinsufficiency impairs the development, but enhances the functional responses, of MZ B cells |
| Q34105275 | Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene |
| Q45299573 | CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers |
| Q24657562 | CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche |
| Q34091303 | Cell-cycle regulation in immunity, tolerance and autoimmunity |
| Q36403689 | Characterization of marginal zone B cell precursors |
| Q40171506 | Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies |
| Q92254268 | Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation |
| Q37725430 | Clinical consequences of defects in B-cell development. |
| Q39684309 | Concerted action of Helios and Ikaros controls the expression of the inositol 5-phosphatase SHIP. |
| Q34612044 | Critical function of Ikaros in controlling Aiolos gene expression |
| Q37829668 | Cutting-edge issues in primary biliary cirrhosis |
| Q58618295 | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN |
| Q84640655 | Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus |
| Q36931139 | Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival |
| Q92321989 | Enhancer jungles establish robust tissue-specific regulatory control in the human genome |
| Q24290205 | Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities |
| Q28142450 | Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system |
| Q34617154 | Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells |
| Q79935229 | Expression of a non-DNA-binding Ikaros isoform exclusively in B cells leads to autoimmunity but not leukemogenesis |
| Q41819249 | Expression of a non-DNA-binding isoform of Helios induces T-cell lymphoma in mice. |
| Q30840381 | Expression of a unique helios isoform in human leukemia cells |
| Q44004531 | Expression of the Ikaros gene family in childhood acute lymphoblastic leukaemia |
| Q47375819 | Expression patterns of Ikaros family members during positive selection and lineage commitment of human thymocytes |
| Q64249673 | Functional SNPs in the Human Autoimmunity-Associated Locus 17q12-21 |
| Q24672799 | Functional heterogeneity of marginal zone B cells revealed by their ability to generate both early antibody-forming cells and germinal centers with hypermutation and memory in response to a T-dependent antigen |
| Q24554337 | Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1 |
| Q90316003 | Genetic Variants Predisposing Most Strongly to Type 1 Diabetes Diagnosed Under Age 7 Years Lie Near Candidate Genes That Function in the Immune System and in Pancreatic β-Cells |
| Q55122554 | Genetic mapping and allelic loss analysis in mouse thymic lymphomas of Helios and Aiolos belonging to the Ikaros gene family. |
| Q36593309 | Genetics of SLE in mice |
| Q28943317 | Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis |
| Q90450495 | Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4CRBN activity |
| Q90016822 | Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases |
| Q34576408 | Haematopoietic cell-fate decisions, chromatin regulation and ikaros |
| Q36387212 | Helios Controls a Limited Subset of Regulatory T Cell Functions |
| Q33934058 | Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression |
| Q90090696 | Helios: still behind the clouds |
| Q55031004 | Heterogeneity of Memory Marginal Zone B Cells. |
| Q44433169 | Histone acetylation-mediated regulation of genes in leukaemic cells. |
| Q34251143 | Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response |
| Q22010766 | Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping |
| Q36121801 | IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools |
| Q48006866 | Identification of sequence variants influencing immunoglobulin levels. |
| Q28141631 | Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes |
| Q64891289 | Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation. |
| Q34119822 | Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression |
| Q43173456 | Ikaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes |
| Q40315519 | Ikaros has a crucial role in regulation of B cell receptor signaling. |
| Q42804218 | Ikaros in B cell development and function |
| Q37796303 | Ikaros in immune receptor signaling, lymphocyte differentiation, and function. |
| Q28141911 | Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity |
| Q48167019 | Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation |
| Q35848777 | Ikaros is required for plasmacytoid dendritic cell differentiation |
| Q77328523 | Ikaros sets thresholds for T cell activation and regulates chromosome propagation |
| Q34197736 | Ikaros, Aiolos and Helios: transcription regulators and lymphoid malignancies |
| Q35064910 | Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). |
| Q43892008 | Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. |
| Q55172908 | Integrative Analysis Identifies Genetic Variants Associated With Autoimmune Diseases Affecting Putative MicroRNA Binding Sites. |
| Q36407229 | Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development |
| Q35750923 | Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells |
| Q60626726 | IκBα is required for marginal zone B cell lineage development |
| Q49990220 | Loss of B Cell Anergy in Type 1 Diabetes is Associated with High Risk HLA and non-HLA Disease Susceptibility Alleles. |
| Q52656903 | Loss of the zona pellucida-binding protein 2 (Zpbp2) gene in mice impacts airway hypersensitivity and lung lipid metabolism in a sex-dependent fashion. |
| Q91770829 | MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition |
| Q44296985 | Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens |
| Q28201000 | Marginal-zone B cells |
| Q40054832 | Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| Q36544048 | New insights into the cell biology of the marginal zone of the spleen |
| Q28509932 | Normal B-1a cell development requires B cell-intrinsic NFATc1 activity |
| Q28594415 | Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells |
| Q34197865 | Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development |
| Q36376076 | Nuclear factor kappa B is required for the development of marginal zone B lymphocytes |
| Q28208976 | OCA-B regulation of B-cell development and function |
| Q34122448 | Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia |
| Q36570655 | Pax5--a critical inhibitor of plasma cell fate |
| Q34807009 | Peripheral natural killer cell maturation depends on the transcription factor Aiolos |
| Q55266542 | Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus. |
| Q34450168 | Plasma cells: finding new light at the end of B cell development |
| Q35666712 | Positive selection and lineage commitment during peripheral B-lymphocyte development |
| Q42159094 | Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs. |
| Q40376217 | Pre-B cell receptor signaling in acute lymphoblastic leukemia |
| Q44225397 | Quantification of human Aiolos splice variants by real-time PCR. |
| Q38350712 | Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development |
| Q36399448 | Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A |
| Q81821256 | Recruitment and selection of marginal zone B cells is independent of exogenous antigens |
| Q35633374 | Recruitment of a distinct but related set of VH sequences into the murine CD21hi/CD23- marginal zone B cell repertoire to that seen in the class-switched antibody response. |
| Q35101899 | Regulation of B cell development by Notch/RBP-J signaling |
| Q35014068 | Regulation of B-cell fate by antigen-receptor signals |
| Q34577054 | Regulation of phospholipase C-gamma2 and phosphoinositide 3-kinase pathways by adaptor proteins in B lymphocytes |
| Q36853407 | Repertoire-based selection into the marginal zone compartment during B cell development |
| Q24534154 | Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes |
| Q27024290 | Rethinking mechanisms of autoimmune pathogenesis |
| Q45248363 | Sequencing-based approach identified three new susceptibility loci for psoriasis |
| Q38804856 | Signaling proteins and transcription factors in normal and malignant early B cell development. |
| Q33381545 | Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1. |
| Q42249912 | Skewed B cell differentiation affects lymphoid organogenesis but not T cell-mediated autoimmunity |
| Q34146100 | Specific in vivo deletion of B-cell subpopulations expressing human immunoglobulins by the B-cell superantigen protein L. |
| Q46491199 | Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement |
| Q50013527 | Stage-specific control of early B cell development by the transcription factor Ikaros |
| Q92445194 | Suppression of Aiolos and Ikaros expression by lenalidomide reduces human ILC3-ILC1/NK cell transdifferentiation |
| Q86420041 | Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B cells |
| Q64067955 | Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle |
| Q37570592 | TNF-α blockade induces IL-10 expression in human CD4+ T cells |
| Q34646688 | Tec kinase pathways in lymphocyte development and transformation |
| Q44012288 | The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for formation of a symmetric flat leaf lamina, encodes a member of a novel family of proteins characterized by cysteine repeats and a leucine zipper. |
| Q51033020 | The CD8alpha gene locus is regulated by the Ikaros family of proteins. |
| Q28591488 | The Ikaros family protein Eos associates with C-terminal-binding protein corepressors |
| Q24291916 | The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis |
| Q37333682 | The bone marrow perisinusoidal niche for recirculating B cells and the positive selection of bone marrow-derived B lymphocytes |
| Q33657947 | The chosen few? Positive selection and the generation of naive B lymphocytes |
| Q35064177 | The combined expression patterns of Ikaros isoforms characterize different hematological tumor subtypes |
| Q38002486 | The diverse roles of IRF4 in late germinal center B-cell differentiation |
| Q73923494 | The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21 |
| Q39225226 | The making of a lymphocyte: the choice among disparate cell fates and the IKAROS enigma |
| Q37237457 | Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes |
| Q33745076 | Transcription factors in hematopoiesis |
| Q78170515 | Transcription factors in lymphocyte development--T and B cells get together |
| Q52319664 | Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. |
| Q44114694 | Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow |
| Q36146925 | Transcriptional networks in developing and mature B cells |
| Q34626885 | Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development |
| Q37360231 | Variations in mRNA and protein levels of Ikaros family members in pediatric T cell acute lymphoblastic leukemia |
| Q88400647 | Zinc finger-IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell |
| Q57024673 | is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice |
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