Regulation of nephron water and electrolyte transport by adenylyl cyclases

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Regulation of nephron water and electrolyte transport by adenylyl cyclases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPRENAL.00656.2013
P932PMC publication ID3962601
P698PubMed publication ID24477683
P5875ResearchGate publication ID259985370

P50authorTimo RiegQ56995678
P2093author name stringDonald E Kohan
P2860cites workOlfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulationQ24316710
Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functionsQ27022162
Intracellular cAMP signaling by soluble adenylyl cyclase.Q27691286
Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCCQ28278647
Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubuleQ28281414
Cellular localization of type 5 and type 6 ACs in collecting duct and regulation of cAMP synthesisQ28567878
cAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase AQ28570785
Protein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac IQ28582549
Association of soluble adenylyl cyclase with the V-ATPase in renal epithelial cellsQ28583885
Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)Q28590267
Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney DiseaseQ29037884
Tolvaptan in autosomal dominant polycystic kidney disease: three years' experienceQ30424687
G protein-coupled prostanoid receptors and the kidneyQ31963761
Characterization of vasopressin-responsive collecting duct adenylyl cyclases in the mouseQ33783994
Calmodulin is required for vasopressin-stimulated increase in cyclic AMP production in inner medullary collecting duct.Q33912091
Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cellsQ34100251
Regulation by Ca2+-signaling pathways of adenylyl cyclasesQ34413032
Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medullaQ34457128
Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sitesQ34518030
Effects of Dopamine on Kidney FunctionQ34982661
Stimulation of renin secretion by catecholamines is dependent on adenylyl cyclases 5 and 6.Q35019728
Distribution of calcitonin-sensitive adenylate cyclase activity along the rabbit kidney tubuleQ35030910
Renal adenylate cyclase and the interrelationship between parathyroid hormone and vitamin D in the regulation of urinary phosphate and adenosine cyclic 3',5'-monophosphate excretionQ35198287
Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cellsQ35372931
Effects of parathyroid hormone on plasma and urinary adenosine 3′,5′-monophosphate in manQ35582246
Collecting duct-specific knockout of adenylyl cyclase type VI causes a urinary concentration defect in mice.Q35652098
Inhibitors of membranous adenylyl cyclasesQ35740305
Inhibitory effects of hypermagnesemia on the renal action of parathyroid hormoneQ35905232
Parathyroid hormone stimulates juxtaglomerular cell cAMP accumulation without stimulating renin releaseQ36312630
Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic miceQ36312680
The distal nephron of rat kidney: a target site for glucagonQ36393686
Molecular pathogenesis of autosomal dominant polycystic kidney diseaseQ36413041
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Class III adenylyl cyclases: molecular mechanisms of catalysis and regulationQ36512195
Transcriptional profiling of native inner medullary collecting duct cells from rat kidneyQ36512949
Adenylyl cyclase VI mediates vasopressin-stimulated ENaC activity.Q36574749
SPAK differentially mediates vasopressin effects on sodium cotransporters.Q36638355
Vasopressin directly regulates cyst growth in polycystic kidney diseaseQ36667140
Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTHQ36762546
Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase RecyclingQ36838890
Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2.Q36861467
Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomainsQ36872222
Adenylate cyclase responsiveness to hormones in various portions of the human nephronQ37020493
Mechanism of resistance to the phosphaturic effect of the parathyroid hormone in the hamsterQ37043895
Functional expression of the olfactory signaling system in the kidneyQ37100981
Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studiesQ37307356
Epac regulates UT-A1 to increase urea transport in inner medullary collecting ducts.Q37330548
Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signalingQ37415827
Capturing adenylyl cyclases as potential drug targetsQ37428727
Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption.Q37430745
2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discoveryQ37474089
Adenylyl cyclase 6 deficiency ameliorates polycystic kidney diseaseQ37524076
Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure.Q37629189
cAMP: novel concepts in compartmentalised signalling.Q37935260
New paradigms in cAMP signallingQ37956434
Cell biology of vasopressin-regulated aquaporin-2 trafficking.Q38022489
New insights into regulated aquaporin-2 function.Q38121476
PTH sensitive adenyl cyclase activity in different segments of the rabbit nephronQ39919531
Vasopressin dependent adenylate cyclase in single segments of rabbit kidney tubuleQ39964611
Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cellsQ42447398
Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation.Q43223386
Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cellsQ43272349
Differential expression of adenylyl cyclases in the rat nephronQ43725710
Chronic exposure to vasopressin upregulates ENaC and sodium transport in the rat renal collecting duct and lungQ43801332
Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2).Q46632300
Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC.Q48639974
Dopamine receptors mediating inhibition of the cyclic adenosine monophosphate generating system in the rat renal cortexQ48763689
Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells.Q53580898
Glomerular podocytes express type 1 adenylate cyclase: inactivation results in susceptibility to proteinuria.Q54394528
Mechanisms mediating the diuretic and natriuretic actions of the incretin hormone glucagon-like peptide-1.Q54588963
Primary cilia and signaling pathways in mammalian development, health and disease.Q55443025
Autosomal dominant polycystic kidney diseaseQ55898854
Different hormonal target sites along the mouse and rabbit nephronsQ67233762
Urinary cyclic AMP excretion in birds: dependence on parathyroid hormone activityQ67266855
Catecholamine sensitive adenylate cyclase activity in different segments of the rabbit nephronQ67428964
Distribution of vasoactive intestinal peptide-sensitive adenylate cyclase activity along the rabbit nephronQ67940230
Activation of renal adenylate cyclase by forskolin: Assessment of enzymatic activity in animal models of the secondary hyperparathyroid stateQ70167796
Effects of antidiuretic hormone on electrolyte reabsorption and secretion in distal tubules of rat kidneyQ70598691
Effects of vasopressin on water and NaCl transport across the in vitro perfused medullary thick ascending limb of Henle's loop of mouse, rat, and rabbit kidneysQ70651200
Influence of forskolin on the parathyroid hormone dependent adenylate cyclase system of canine kidney: evidence for noncatalytic effects of forskolinQ70798282
Localization of mRNAs encoding Ca2+-inhibitable adenylyl cyclases along the renal tubule. Functional consequences for regulation of the cAMP contentQ71245747
Stimulation by antidiuretic hormone of electrolyte tubular reabsorption in rat kidneyQ71658154
Effect of prostaglandin E2 on agonist-stimulated cAMP accumulation in the distal convoluted tubule isolated from the rabbit kidneyQ72076586
Expression of adenylyl cyclase mRNAs in the adult, in developing, and in the Brattleboro rat kidneyQ73575633
Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidneyQ78223119
Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonistQ79075547
Epac-mediated Ca(2+) mobilization and exocytosis in inner medullary collecting ductQ83310188
Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranesQ83327050
Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 StudyQ83442994
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)F701-9
P577publication date2014-01-29
P1433published inAmerican Journal of Physiology - Renal PhysiologyQ2610177
P1476titleRegulation of nephron water and electrolyte transport by adenylyl cyclases
P478volume306

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cites work (P2860)
Q89013192A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector
Q63384108Adenylyl cyclase 6 is required for maintaining acid–base homeostasis
Q92164067Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion
Q93030100Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial
Q37139683Heterotrimeric G protein signaling in polycystic kidney disease
Q47831593Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.
Q39158851International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.
Q39507691Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure
Q38654032Regulation of Mg2+ Reabsorption and Transient Receptor Potential Melastatin Type 6 Activity by cAMP Signaling
Q34568797Renal phosphate wasting in the absence of adenylyl cyclase 6
Q57184176Role of calcium in adult onset polycystic kidney disease
Q37078837STIM1fl/fl Ksp-Cre Mouse has Impaired Renal Water Balance
Q38334631The nucleobase adenine as a signalling molecule in the kidney.