Regulation of Mg2+ Reabsorption and Transient Receptor Potential Melastatin Type 6 Activity by cAMP Signaling

scientific article

Regulation of Mg2+ Reabsorption and Transient Receptor Potential Melastatin Type 6 Activity by cAMP Signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2014121228
P932PMC publication ID4769198
P698PubMed publication ID26150606
P5875ResearchGate publication ID279862005

P50authorMaxime G. BlanchardQ39648119
Jeroen H F de BaaijQ83593923
P2093author name stringJoost G J Hoenderop
René J M Bindels
Donald E Kohan
Wararat Kittikulsuth
Jonathan R Genzen
Anil V Nair
Femke Latta
P2860cites workCalbindin-D28K dynamically controls TRPV5-mediated Ca2+ transportQ24293026
RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domainQ24311850
Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7Q24684596
Regulation of nephron water and electrolyte transport by adenylyl cyclasesQ27023655
X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coilQ27652067
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene familyQ28200813
Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemiaQ28200829
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorptionQ28212198
Molecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormoneQ28742753
Magnesium transport in the renal distal convoluted tubuleQ31817101
Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.Q33325491
Methionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stressQ34074303
Loss of insulin-induced activation of TRPM6 magnesium channels results in impaired glucose tolerance during pregnancyQ34317153
Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansionQ34502911
Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel ActivityQ35182091
Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activityQ35614894
Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7.Q35617860
Magnesium basicsQ35683770
Regulation of magnesium balance: lessons learned from human genetic diseaseQ35683775
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemiaQ35916097
An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.Q36247097
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.Q36295896
Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels.Q36681735
Regulation of TRP channels: a voltage-lipid connection.Q36711381
TRPM7 is regulated by halides through its kinase domainQ37008898
Functional expression of the olfactory signaling system in the kidneyQ37100981
Parathyroid hormone activates TRPV5 via PKA-dependent phosphorylationQ37297663
Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studiesQ37307356
Mice defective in Trpm6 show embryonic mortality and neural tube defectsQ37397411
The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channelsQ37596387
Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure.Q37629189
New TRPM6 missense mutations linked to hypomagnesemia with secondary hypocalcemiaQ37636734
Molecular basis of epithelial Ca2+ and Mg2+ transport: insights from the TRP channel familyQ37805923
Insight into renal Mg2+ transporters.Q37824574
Magnesium in man: implications for health and diseaseQ38300459
Lack of an effect of nephron-specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressureQ39507691
Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interactionQ39578555
Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA).Q39867051
Role of the alpha-kinase domain in transient receptor potential melastatin 6 channel and regulation by intracellular ATP.Q39980643
Molecular determinants of permeation through the cation channel TRPM6.Q40209520
Rapid vesicular translocation and insertion of TRP channelsQ40534350
Effects of the EGFR Inhibitor Erlotinib on Magnesium HandlingQ42173242
Insulin stimulates Mg2+ uptake in mouse distal convoluted tubule cellsQ42481243
EGF increases TRPM6 activity and surface expressionQ43210203
Differential expression of adenylyl cyclases in the rat nephronQ43725710
Acid-base status determines the renal expression of Ca2+ and Mg2+ transport proteins.Q46900080
The epithelial Mg2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg2+ content and estrogensQ46981321
Elucidation of the distal convoluted tubule transcriptome identifies new candidate genes involved in renal Mg(2+) handling.Q50471741
Cisplatin-induced injury of the renal distal convoluted tubule is associated with hypomagnesaemia in mice.Q54284519
Transient Receptor Potential Melastatin 6 Knockout Mice Are Lethal whereas Heterozygous Deletion Results in Mild HypomagnesemiaQ84977093
P2X4 receptor regulation of transient receptor potential melastatin type 6 (TRPM6) Mg2+ channelsQ87077916
P433issue3
P304page(s)804-813
P577publication date2015-07-06
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleRegulation of Mg2+ Reabsorption and Transient Receptor Potential Melastatin Type 6 Activity by cAMP Signaling
P478volume27

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cites work (P2860)
Q38695340A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients with CLDN10 Mutations
Q47726302Genetics of Magnesium Disorders
Q47981534Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression.
Q41524357Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells.
Q36703547Role of renal TRP channels in physiology and pathology
Q90460055Single-molecule labeling for studying trafficking of renal transporters
Q99610232TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity
Q51024750Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.

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