Lipid mediators and allergic diseases

scientific article

Lipid mediators and allergic diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ANAI.2013.06.031
P932PMC publication ID4088989
P698PubMed publication ID23987187

P2093author name stringJoshua A. Boyce
Laura B. Fanning
P2860cites workA double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patientsQ74789102
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Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammationQ37286185
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The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trialQ38463456
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PGE(2) receptor (EP(4)) agonists: potent dilators of human bronchi and future asthma therapy?Q39664542
In vitro and in vivo effects of leukotriene B4 antagonism in a primate model of asthmaQ39758020
Pharmacological interactions between prostacyclin and thromboxanesQ40137633
Effect of Oral Administration of A Prostacyclin Analog (Op-41483) On Pulmonary Function and Bronchial Responsiveness in Stable Asthmatic SubjectsQ41948877
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Release of prostaglandin D2 into human airways during acute antigen challengeQ42216102
Persistent increase in plasma and urinary leukotrienes after acute asthmaQ42375124
Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.Q42512398
Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial GroupQ42556993
Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primatesQ43136931
Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Effect of indomethacinQ43536142
Evidence for elevated levels of histamine, prostaglandin D2, and other bronchoconstricting prostaglandins in the airways of subjects with mild asthmaQ43658945
Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjectsQ43669689
Anti-eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitisQ43686203
A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma modelQ43846995
Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in miceQ43961084
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjectsQ44241228
Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cellsQ44325026
Role of prostaglandin I2 in airway remodeling induced by repeated allergen challenge in miceQ44391228
Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR.Q44470098
Effects of inhaled corticosteroids on exhaled leukotrienes and prostanoids in asthmatic childrenQ45103516
Dissociation of airway inflammation and hyperresponsiveness by cyclooxygenase inhibition in allergen challenged miceQ46104730
Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3.Q46418233
Augmentation of allergic inflammation in the airways of cyclooxygenase-2-deficient miceQ46432048
Prostaglandin E2 protects lower airways against bronchoconstrictionQ46661216
Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1.Q47581798
Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responsesQ47724295
Accentuated T helper type 2 airway response after allergen challenge in cyclooxygenase-1-/- but not cyclooxygenase-2-/- mice.Q51683175
EP(2) receptor mediates bronchodilation by PGE(2) in mice.Q52539531
A novel prostacyclin agonist protects against airway hyperresponsiveness and remodeling in mice.Q53180552
E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E2.Q54593169
Induced Sputum Eicosanoid Concentrations in AsthmaQ55094021
The Pivotal Role of 5-Lipoxygenase Products in the Reaction of Aspirin-sensitive Asthmatics to AspirinQ57240791
Effect of Inhaled Prostaglandin E2on Allergen-induced AsthmaQ57415843
Inflammatory mediator release on conjunctival provocation of allergic subjects with allergenQ67657662
Urinary Leukotriene E4Concentrations Increase after Aspirin Challenge in Aspirin-sensitive Asthmatic SubjectsQ67915846
Thromboxane A2 biosynthesis in acute asthma and after antigen challengeQ68181110
Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutationQ24562692
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytesQ24633568
Why there are two cyclooxygenase isozymesQ27863307
BLT1 and BLT2: the leukotriene B(4) receptorsQ28191625
Leukotriene-receptor expression on nasal mucosal inflammatory cells in aspirin-sensitive rhinosinusitisQ28194143
Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitisQ28219122
Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouseQ28238317
Regulating leukotriene synthesis: the role of nuclear 5-lipoxygenaseQ28276459
Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligandQ28287399
The Leukotrienes: Immune-Modulating Lipid Mediators of DiseaseQ29036681
Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregationQ30442280
Prostanoid receptors: subtypes and signalingQ34192781
Phospholipase A(2).Q34219384
Cloning and Characterization of the Human Leukotriene A4 Hydrolase GeneQ34301660
The phospholipase A2 superfamily and its group numbering systemQ34566140
CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cellsQ34662206
Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienesQ34681509
Augmentation of allergic inflammation in prostanoid IP receptor deficient miceQ35044600
Prostaglandin E2 activates EP2 receptors to inhibit human lung mast cell degranulationQ35545787
EP4 receptor as a new target for bronchodilator therapyQ35564982
Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradationQ35660728
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammationQ35663953
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinicQ35760394
Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responsesQ35841909
T-cell trafficking in asthma: lipid mediators grease the way.Q35877210
Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammationQ36140425
Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cellsQ36229711
Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammationQ36339008
The importance of leukotrienes in airway inflammation in a mouse model of asthmaQ36367477
Prostaglandin D2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokineQ36371613
Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammationQ36420377
Pulmonary responses to bronchoconstrictor agonists in the mouseQ69034596
Effect of indomethacin on allergen-induced asthmatic responsesQ69190652
Thromboxane biosynthesis in allergen-induced bronchospasm. Evidence for platelet activationQ69240613
The major source of endogenous prostaglandin D2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissuesQ69244268
Mediator release after nasal airway challenge with allergenQ70287869
Bronchoconstrictor effects of leukotriene C in humansQ70298182
Comparative bronchoconstrictor effects of histamine, leukotriene C, and leukotriene D in normal human volunteersQ70629252
Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthmaQ70897542
Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthmaQ70906164
Acute and chronic effects of a 5-lipoxygenase inhibitor in asthma: a 6-month randomized multicenter trial. Zileuton Study GroupQ71823499
Leukotriene C4 formation by transcellular biosynthesisQ72029852
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjectsQ72252746
Eicosanoids in bronchoalveolar lavage fluid of aspirin-intolerant patients with asthma after aspirin challengeQ72328568
Prostaglandin D2-induced bronchoconstriction is mediated only in part by the thromboxane prostanoid receptorQ72332303
Effect of inhaled PGE2 on exercise-induced bronchoconstriction in asthmatic subjectsQ72398978
Increased Production of Prostaglandin D2 in Patients with Systemic MastocytosisQ72437053
Cutting edge: differential production of prostaglandin D2 by human helper T cell subsetsQ73458387
5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in miceQ73519746
Cyclooxygenase inhibition increases interleukin 5 and interleukin 13 production and airway hyperresponsiveness in allergic miceQ74139304
Effect of thromboxane A2 inhibitors on allergic pulmonary inflammation in miceQ74575532
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)155-62
P577publication date2013-09-01
P1433published inAnnals of Allergy, Asthma & ImmunologyQ13429696
P1476titleLipid mediators and allergic diseases
P478volume111

Reverse relations

cites work (P2860)
Q37519095A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice
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Q26767423Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
Q38693289Cytochrome P450 and Lipoxygenase Metabolites on Renal Function
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Q90191790Gut Microbial-Derived Metabolomics of Asthma
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Q33801028In vivo metabolite profiling as a means to identify uncharacterized lipase function: recent success stories within the alpha beta hydrolase domain (ABHD) enzyme family
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