Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

scientific article

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FREERADBIOMED.2011.09.030
P3181OpenCitations bibliographic resource ID671538
P932PMC publication ID3911769
P698PubMed publication ID22027063
P5875ResearchGate publication ID51745112

P50authorVictor Darley-UsmarQ7925839
Kelvin J. A. DaviesQ56851069
Henry Jay FormanQ16729048
Phyllis A. DenneryQ41817140
P2093author name stringKevin Moore
Harry Ischiropoulos
L Jackson Roberts
Balaraman Kalyanaraman
Matthew B Grisham
Giovanni E Mann
P2860cites workEvaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stressQ67493487
Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophilsQ72801554
Oxidation of 2',7'-dichlorofluorescin by peroxynitriteQ73831038
Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping studyQ77988221
Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Q78115652
The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy?Q82842541
Genetically encoded fluorescent indicator for intracellular hydrogen peroxideQ82918322
Reconciling the chemistry and biology of reactive oxygen speciesQ29615709
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasisQ29617340
Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truthQ30457642
A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cellsQ33548893
Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide: direct reaction with boronate-based fluorescent probeQ33825005
Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescenceQ33937018
Boronate-based fluorescent probes for imaging cellular hydrogen peroxideQ34565753
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrixQ35549813
Unraveling the biological roles of reactive oxygen speciesQ35653213
Oxidant-induced iron signaling in Doxorubicin-mediated apoptosisQ35708066
Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathwayQ35977324
Measurement of reactive oxygen species in cardiovascular studiesQ36012674
"ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"--a critical commentaryQ36679129
Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation by recombinant microsomal enzymesQ36814285
Methods to measure the reactivity of peroxynitrite-derived oxidants toward reduced fluoresceins and rhodaminesQ37191435
Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimersQ37216195
What does the commonly used DCF test for oxidative stress really show?Q39724296
Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: implications for quantifying peroxynitrite formation in cellsQ39922740
Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine.Q40025505
Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.Q41604091
Direct oxidation of boronates by peroxynitrite: mechanism and implications in fluorescence imaging of peroxynitrite.Q42202476
A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipidsQ42538987
Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosisQ43550916
Reaction of superoxide and nitric oxide with peroxynitrite. Implications for peroxynitrite-mediated oxidation reactions in vivoQ43617482
Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosisQ44274556
Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxideQ44448203
Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cellsQ46417523
The selective detection of mitochondrial superoxide by live cell imagingQ46554007
P4510describes a project that usesfluorescent probeQ12016716
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectnitrogenQ627
oxygenQ629
P304page(s)1-6
P577publication date2011-10-02
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleMeasuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations
P478volume52

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Q36917888Mechanical stress and ATP synthesis are coupled by mitochondrial oxidants in articular cartilage
Q46572554Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies.
Q33789277Mechanisms of neurovascular dysfunction in acute ischemic brain
Q35294224Melatonin enhances photo-oxidation of 2',7'-dichlorodihydrofluorescein by an antioxidant reaction that renders N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).
Q57554908Metabolic enhancers supporting 1-carbon cycle affect sperm functionality: an in vitro comparative study
Q36720566Methods for assessing mitochondrial function in diabetes
Q37460117Methods for detection of mitochondrial and cellular reactive oxygen species
Q46736926MicroRNA-155 aggravates ischemia-reperfusion injury by modulation of inflammatory cell recruitment and the respiratory oxidative burst
Q38829042MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression
Q35912784Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation.
Q38113136Mitochondria as oxidative signaling organelles in T-cell activation: physiological role and pathological implications
Q39400621Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications.
Q41905722Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity
Q36736460Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo
Q46254796Mitochondrial GSH Systems in CA1 Pyramidal Cells and Astrocytes React Differently during Oxygen-Glucose Deprivation and Reperfusion
Q36936220Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation
Q52627693Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning.
Q38615068Mitochondrial ROS signaling in organismal homeostasis
Q90453327Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy
Q64966341Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington's disease patients.
Q39191013Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage
Q47276489Mitochondrial haplogroups in patients with rheumatoid arthritis: No association with disease and disease manifestations
Q37427280Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.
Q26753177Mitochondrial reactive oxygen species: Do they extend or shorten animal lifespan?
Q39270199Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells
Q59797049Mitoproteomics: Tackling Mitochondrial Dysfunction in Human Disease
Q46793119MnTM-4-PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stress.
Q28391060Model combustion-generated particulate matter containing persistent free radicals redox cycle to produce reactive oxygen species
Q46378959Molecular Basis for Exercise-Induced Fatigue: The Importance of Strictly Controlled Cellular Ca(2+) Handling
Q38831360Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria
Q37460376Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models.
Q46262818Molecular photoprotection of human keratinocytes in vitro by the naturally occurring mycosporine-like amino acid (MAA) palythine.
Q33637092Monitoring Cr intermediates and reactive oxygen species with fluorescent probes during chromate reduction
Q58797739Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe
Q35091005Moving free radical and redox biology ahead in the next decade(s)
Q46273977Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo.
Q35861302Multiscattering-enhanced optical biosensor: multiplexed, non-invasive and continuous measurements of cellular processes
Q58742990Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation
Q48045759N-Heterocyclic Carbene Boranes as Reactive Oxygen Species-Responsive Materials: Application to the Two-Photon Imaging of Hypochlorous Acid in Living Cells and Tissues.
Q36501270NADPH oxidase 4 is required for interleukin-1β-mediated activation of protein kinase Cδ and downstream activation of c-jun N-terminal kinase signaling in smooth muscle
Q28389251NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease
Q28072348NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?
Q37254291NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy
Q36175713NOX2-dependent ROS is required for HDAC5 nuclear efflux and contributes to HDAC4 nuclear efflux during intense repetitive activity of fast skeletal muscle fibers
Q60023160Nano-metal oxides induce antimicrobial resistance via radical-mediated mutagenesis
Q89468697Nanoparticle formulation and in vitro efficacy testing of the mitoNEET ligand NL-1 for drug delivery in a brain endothelial model of ischemic reperfusion-injury
Q46361618Nanoparticle-induced oxidation of corona proteins initiates an oxidative stress response in cells
Q57496811Near-infrared fluorescence probes to detect reactive oxygen species for keloid diagnosis
Q47233510Necrostatin-1 Protects Against Paraquat-Induced Cardiac Contractile Dysfunction via RIP1-RIP3-MLKL-Dependent Necroptosis Pathway
Q64079076Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O Consumption and ROS Release
Q54261956Neutrophil-generated HOCl leads to non-specific thiol oxidation in phagocytized bacteria.
Q90176041New Insights About Doxorubicin-Induced Toxicity to Cardiomyoblast-Derived H9C2 Cells and Dexrazoxane Cytoprotective Effect: Contribution of In Vitro 1H-NMR Metabonomics
Q46591312New insights into ROS dynamics: a multi-layered microfluidic chip for ecotoxicological studies on aquatic microorganisms
Q38232958New reagents for detecting free radicals and oxidative stress
Q28384525Nickel Release, ROS Generation and Toxicity of Ni and NiO Micro- and Nanoparticles
Q59800926Nicotine and Cotinine Inhibit Catalase and Glutathione Reductase Activity Contributing to the Impaired Osteogenesis of SCP-1 Cells Exposed to Cigarette Smoke
Q37133470Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance
Q33931109Nitrosothiol formation and protection against Fenton chemistry by nitric oxide-induced dinitrosyliron complex formation from anoxia-initiated cellular chelatable iron increase
Q90650790Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes
Q35000274Novel recombinant human lactoferrin: differential activation of oxidative stress related gene expression
Q35070877Novel targets of sulforaphane in primary cardiomyocytes identified by proteomic analysis
Q91896653Nrf2 Activation Protects Mouse Beta Cells from Glucolipotoxicity by Restoring Mitochondrial Function and Physiological Redox Balance
Q99574518Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation
Q28393187Nutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidence
Q36697347Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study
Q48133236Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling
Q41815199On reactive oxygen species measurement in living systems.
Q41945075On the use of fluorescence lifetime imaging and dihydroethidium to detect superoxide in intact animals and ex vivo tissues: a reassessment.
Q38172636One-dimensional nanoprobes for single-cell studies
Q61798304Optimization of Experimental Settings for the Assessment of Reactive Oxygen Species Production by Human Blood
Q37587840Optogenetic control of ROS production
Q39118120Overexpression of Helicobacter pylori VacA N-terminal fragment induces proinflammatory cytokine expression and apoptosis in human monocytic cell line through activation of NF-κB.
Q41850704Overexpression of catalase in vascular smooth muscle cells prevents the formation of abdominal aortic aneurysms
Q37643688Oxidative Stress and Huntington's Disease: The Good, The Bad, and The Ugly
Q28077167Oxidative Stress during HIV Infection: Mechanisms and Consequences
Q51760895Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer's Disease.
Q35760065Oxidative inhibition of the vascular Na+-K+ pump via NADPH oxidase-dependent β1-subunit glutathionylation: implications for angiotensin II-induced vascular dysfunction
Q38222160Oxidative stress and antibiotic resistance in bacterial pathogens: state of the art, methodologies, and future trends
Q31044181Oxidative stress and antioxidative systems: recipes for successful data collection and interpretation
Q30770438Oxidative stress decreases microtubule growth and stability in ventricular myocytes
Q38797529Oxidative stress does not play a primary role in the toxicity induced with clinical doses of doxorubicin in myocardial H9c2 cells.
Q41007953Oxidative stress induced in E. coli by the human antimicrobial peptide LL-37.
Q28541225Oxidative stress is a mediator for increased lipid accumulation in a newly isolated Dunaliella salina strain
Q37375576Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C. elegans
Q41342988Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib
Q28387368Oxidative stress, redox signaling, and autophagy: cell death versus survival
Q38261245Oxidatively generated damage to cellular DNA by UVB and UVA radiation
Q45294879Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells--protective effect of cystamine and creatine
Q52558564Oxygen-dependence of mitochondrial ROS production as detected by Amplex Red assay.
Q46254007Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift.
Q34805453Paranode Abnormalities and Oxidative Stress in Optic Nerve Vulnerable to Secondary Degeneration: Modulation by 670 nm Light Treatment
Q64259359Peptides from Cauliflower By-Products, Obtained by an Efficient, Ecosustainable, and Semi-Industrial Method, Exert Protective Effects on Endothelial Function
Q92921857Peripheral Blood Mononuclear Cells and Platelets Mitochondrial Dysfunction, Oxidative Stress, and Circulating mtDNA in Cardiovascular Diseases
Q89135839Peroxiredoxin 6 is the primary antioxidant enzyme for the maintenance of viability and DNA integrity in human spermatozoa
Q35211458Persistent oxidative stress in human neural stem cells exposed to low fluences of charged particles
Q37497833Pharmacological approaches to restore mitochondrial function
Q28544712Phospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effect
Q36407761Photooxidation of Amplex Red to resorufin: implications of exposing the Amplex Red assay to light
Q39419192Platelets redox balance assessment: Current evidence and methodological considerations.
Q34432247Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1.
Q57760906Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
Q37499325Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.
Q36630737Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols
Q36188483Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation
Q37712651Production of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes
Q36103810Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells
Q46551006Protective Effects of Chlorogenic Acid and its Metabolites on Hydrogen Peroxide-Induced Alterations in Rat Brain Slices: A Comparative Study with Resveratrol
Q97419620Protective effect of maternal exercise against amyloid-β neurotoxicity in the male rat offspring's cerebellum
Q58577549Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage
Q33881508Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension
Q89574949Pyrocatalysis-The DCF assay as a pH-robust tool to determine the oxidation capability of thermally excited pyroelectric powders
Q88557318QSOX1, a novel actor of cardiac protection upon acute stress in mice
Q46473243Quantification of hydrogen peroxide in plant tissues using Amplex Red.
Q38865515Quantifying ROS levels using CM-H2DCFDA and HyPer.
Q41742488Quantifying intracellular hydrogen peroxide perturbations in terms of concentration
Q90483713Quantitative analysis of H2O2 transport through purified membrane proteins
Q38478574ROS signaling and redox biology in endothelial cells
Q46380661ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis
Q88789099ROS-triggered degradable iron-chelating nanogels: Safely improving iron elimination in vivo
Q96110831Radioprotection of thymine and calf thymus DNA by an azo compound: mechanism of action followed by DPPH radical quenching & ROS depletion in WI 38 lung fibroblast cells
Q38872178Radioresistant Sf9 insect cells display efficient antioxidant defence against high dose γ-radiation.
Q42962950Rapid and specific measurements of superoxide using fluorescence spectroscopy
Q92952015Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species
Q35872003Reactive Oxygen Species and Mitochondrial DNA Damage and Repair in BCR-ABL1 Cells Resistant to Imatinib
Q27002524Reactive oxygen species adversely impacts bone marrow microenvironment in diabetes
Q35035263Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension
Q39101971Reactive oxygen species mediate dopamine-induced signaling in renal proximal tubule cells
Q35701794Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
Q46598784Reactive oxygen/nitrogen species and contractile function in skeletal muscle during fatigue and recovery
Q40538739Real-Time H2 O2 Measurements in Bone Marrow Mesenchymal Stem Cells (MSCs) Show Increased Antioxidant Capacity in Cells From Osteoporotic Women
Q36589168Real-time monitoring of superoxide accumulation and antioxidant activity in a brain slice model using an electrochemical cytochrome c biosensor.
Q38785796Recent advances and long-standing problems in detecting oxidative damage and reactive oxygen species in skeletal muscle
Q38056489Recent advances in intracellular and in vivo ROS sensing: focus on nanoparticle and nanotube applications.
Q36005717Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide
Q94951477Redox Modulation and Induction of Ferroptosis as a New Therapeutic Strategy in Hepatocellular Carcinoma
Q90466813Redox basis of exercise physiology
Q26772286Redox biology in pulmonary arterial hypertension (2013 Grover Conference Series)
Q51748168Redox control of cancer cell destruction.
Q33569598Redox environment in stem and differentiated cells: A quantitative approach.
Q38660882Redox homeostasis and age-related deficits in neuromuscular integrity and function.
Q64950048Redox mechanism of levobupivacaine cytostatic effect on human prostate cancer cells.
Q34623170Redox processes inform multivariate transdifferentiation trajectories associated with TGFβ-induced epithelial-mesenchymal transition
Q90505651Redox signalling and ageing: insights from Drosophila
Q47271512Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling
Q38160013Redox-sensitive probes for the measurement of redox chemistries within phagosomes of macrophages and dendritic cells
Q34301883Reducing mitochondrial ROS improves disease-related pathology in a mouse model of ataxia-telangiectasia
Q55084457Regulation of midgut cell proliferation impacts Aedes aegypti susceptibility to dengue virus.
Q36089550Relationship of oxidative stress in skeletal muscle with obesity and obesity-associated hyperinsulinemia in horses.
Q91867535Remarkable Protective Effects of Nrf2-Mediated Antioxidant Enzymes and Tissue Specificity in Different Skeletal Muscles of Daurian Ground Squirrels Over the Torpor-Arousal Cycle
Q35151494Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk
Q92419601Renal Hydrogen Peroxide Production Prevents Salt-Sensitive Hypertension
Q46740136Response to cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity.
Q35123560Responses of solid tumor cells in DMEM to reactive oxygen species generated by non-thermal plasma and chemically induced ROS systems
Q37651683Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance.
Q36988868Resveratrol enhances exercise training responses in rats selectively bred for high running performance
Q59430813Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism
Q91943247Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
Q58705134Ribosomal protein L10 in mitochondria serves as a regulator for ROS level in pancreatic cancer cells
Q92344797Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer's Disease Patients
Q42935873Role of iron, zinc and reduced glutathione in oxidative stress induction by low pH in rat brain synaptosomes.
Q49848328Role of superoxide ion formation in hypothermia/rewarming induced contractile dysfunction in cardiomyocytes
Q58577829Roles of Cytochrome P450 in Metabolism of Ethanol and Carcinogens
Q46066885SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle.
Q36713609SIRT3 Deficiency Induces Endothelial Insulin Resistance and Blunts Endothelial-Dependent Vasorelaxation in Mice and Human with Obesity
Q38850280Safety assessment of nanoparticles for drug delivery by means of classic in vitro assays and beyond
Q92837097Salinity Variation in a Mangrove Ecosystem: A Physiological Investigation to Assess Potential Consequences of Salinity Disturbances on Mangrove Crabs
Q37298983Salinity stress from the perspective of the energy-redox axis: Lessons from a marine intertidal flatworm
Q41879437Sch9 regulates intracellular protein ubiquitination by controlling stress responses
Q37391429Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals
Q38962477Short-term exposure of nontumorigenic human bronchial epithelial cells to carcinogenic chromium(VI) compromises their respiratory capacity and alters their bioenergetic signature
Q27306154Silica particles cause NADPH oxidase-independent ROS generation and transient phagolysosomal leakage
Q36549017Silver nanoparticles disrupt germline stem cell maintenance in the Drosophila testis
Q57524960Site-Specific Detection of Free Radicals in Membranes Using an Amphiphilic Spin Trap
Q52642053Small-molecule luminescent probes for the detection of cellular oxidizing and nitrating species.
Q37007086Sod1 loss induces intrinsic superoxide accumulation leading to p53-mediated growth arrest and apoptosis
Q46543834Sodium nitrite enhances generation of reactive oxygen species that decrease antioxidant power and inhibit plasma membrane redox system of human erythrocytes
Q89487190Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses
Q42488611Spatial compartmentalization of free radical formation and mitochondrial heterogeneity in bivalve gills revealed by live-imaging techniques
Q27305361Spatially-resolved intracellular sensing of hydrogen peroxide in living cells
Q46722577Spatio-temporal changes in glutathione and thioredoxin redox couples during ionizing radiation-induced oxidative stress regulate tumor radio-resistance
Q26742130Standards and Methodologies for Characterizing Radiobiological Impact of High-Z Nanoparticles.
Q60307901Strategies to detect mitochondrial oxidants
Q90729879Sulforaphane Modulates AQP8-Linked Redox Signalling in Leukemia Cells
Q58753042Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase
Q52370260Suppression of reactive oxygen species generation in heart mitochondria from anoxic turtles: the role of complex I S-nitrosation.
Q98735511Supraphysiological Levels of Testosterone Induce Vascular Dysfunction via Activation of the NLRP3 Inflammasome
Q51342557SurR9C84A protects and recovers human cardiomyocytes from hypoxia induced apoptosis.
Q92702163Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators
Q97538280Synergy effect of peroxidase enzymes and Fenton reactions greatly increase the anaerobic oxidation of soil organic matter
Q58022790Synthesis of copper sulfide nanoparticles and evaluation of in vitro antibacterial activity and in vivo therapeutic effect in bacteria-infected zebrafish
Q39140884Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system.
Q41098427Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.
Q21198861Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
Q38826355Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis
Q49182137Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies
Q46280814Techniques for Detecting Reactive Oxygen Species in Pulmonary Vasculature Redox Signaling
Q42762854Tetrathiatriarylmethyl radical with a single aromatic hydrogen as a highly sensitive and specific superoxide probe
Q90537755The Effect of Chronic NO Synthase Inhibition on the Vasoactive and Structural Properties of Thoracic Aorta, NO Synthase Activity, and Oxidative Stress Biomarkers in Young SHR
Q64256652The Effectiveness of Vitamin E Treatment in Alzheimer's Disease
Q31063986The N-B Interaction through a Water Bridge: Understanding the Chemoselectivity of a Fluorescent Protein Based Probe for Peroxynitrite
Q42357075The Na+-Translocating NADH:Quinone Oxidoreductase Enhances Oxidative Stress in the Cytoplasm of Vibrio cholerae.
Q35994328The Oxygen Paradox, oxidative stress, and ageing
Q26750137The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
Q50216101The Role of Maternal Gestational Diabetes in Inducing Fetal Endothelial Dysfunction
Q56918758The UV/Visible Radiation Boundary Region (385-405 nm) Damages Skin Cells and Induces "dark" Cyclobutane Pyrimidine Dimers in Human Skin in vivo
Q38542047The basic chemistry of exercise-induced DNA oxidation: oxidative damage, redox signaling, and their interplay.
Q28395817The cysteine proteome
Q39433767The effect of chronic alcohol consumption on mitochondrial calcium handling in hepatocytes.
Q46941996The essential oil of bergamot stimulates reactive oxygen species production in human polymorphonuclear leukocytes
Q41968307The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species
Q39912879The immediate wound-induced oxidative burst of Saccharina latissima depends on light via photosynthetic electron transport
Q90929632The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II
Q34647344The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke.
Q37679215The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction.
Q64227181The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector
Q89500213The relationships between cytochromes P450 and H2O2: Production, reaction, and inhibition
Q36563042The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches
Q93380986The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines
Q57470162The synergistic bactericidal mechanism of simultaneous 222-nm krypton-chlorine excilamp and 254-nm low-pressure mercury lamp treatment
Q37341998The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration.
Q37617637The use of the Cre/loxP system to study oxidative stress in tissue-specific manganese superoxide dismutase knockout models
Q47401744Three-Dimensional Tissue Models and Available Probes for Multi-Parametric Live Cell Microscopy: A Brief Overview.
Q42127781Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.
Q58708678Thymosin Beta-4 and Ciprofloxacin Adjunctive Therapy Improves -Induced Keratitis
Q36534337Tissue-specific oxidative stress and loss of mitochondria in CoQ-deficient Pdss2 mutant mice.
Q36145679Toll-like receptor 4 signaling: A common pathway for interactions between prooxidants and extracellular disulfide high mobility group box 1 (HMGB1) protein-coupled activation
Q38576820Toward selective detection of reactive oxygen and nitrogen species with the use of fluorogenic probes--Limitations, progress, and perspectives.
Q35854702Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress
Q56531120Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death
Q38221702Tyrosine nitration as mediator of cell death
Q42144812Ultraviolet irradiation increases green fluorescence of dihydrorhodamine (DHR) 123: false-positive results for reactive oxygen species generation
Q110527795Unbiased automated quantitation of ROS signals in live retinal neurons of Drosophila using Fiji/ImageJ
Q37393878Understanding the Antifungal Mechanism of Ag@ZnO Core-shell Nanocomposites against Candida krusei
Q38886231Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation
Q38884895Use of fluorescent probes for ROS to tease apart Type I and Type II photochemical pathways in photodynamic therapy
Q28818468Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress
Q42032738Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.
Q46338690V79 Fibroblasts Are Protected Against Reactive Oxygen Species by Flax Fabric.
Q56418744Variety is the spice of life: how to explore a redox-dependent heterogeneity in genomically identical cellular populations
Q47897172Vascular Endothelial Mitochondrial Function Predicts Death or Pulmonary Outcomes in Preterm Infants.
Q46698435Verminoside mediates life span extension and alleviates stress in Caenorhabditis elegans.
Q48262689Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes.
Q57280435Where in the world do bacteria experience oxidative stress?
Q36076257Wolbachia Do Not Induce Reactive Oxygen Species-Dependent Immune Pathway Activation in Aedes albopictus
Q93082057Yak-Kong Soybean (Glycine max) Fermented by a Novel Pediococcus pentosaceus Inhibits the Oxidative Stress-Induced Monocyte-Endothelial Cell Adhesion
Q91790881Zerumbone Exhibits Antiphotoaging and Dermatoprotective Properties in Ultraviolet A-Irradiated Human Skin Fibroblast Cells via the Activation of Nrf2/ARE Defensive Pathway
Q91783876Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes
Q29248295Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster
Q61443136γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity

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