Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1.

scientific article

Polyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.REDOX.2014.07.001
P932PMC publication ID4215463
P698PubMed publication ID25460732
P5875ResearchGate publication ID264349586

P2093author name stringXavier Pintó
Juan José Moreno
Joan Roselló-Catafau
María Teresa Mitjavila
Carolina Emilia Storniolo
P2860cites workInhibition of Cyclic Strain-Induced Endothelin-1 Gene Expression by ResveratrolQ44659658
Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients.Q44886445
Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: the PREDIMED studyQ45143258
Bioavailability of phenolic compounds from olive oil and oxidative/antioxidant status at postprandial state in healthy humans.Q45257282
Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbetaQ45282771
Acute glucosamine-induced insulin resistance in muscle in vivo is associated with impaired capillary recruitmentQ46628646
Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial.Q55042163
Total polyphenol excretion and blood pressure in subjects at high cardiovascular riskQ57235802
Rapid Folin–Ciocalteu method using microtiter 96-well plate cartridges for solid phase extraction to assess urinary total phenolic compounds, as a biomarker of total polyphenols intakeQ59158053
Analysis of non-esterified fatty acids in human samples by solid-phase-extraction and gas chromatography/mass spectrometryQ62661419
Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veinsQ68499099
Changing the Mediterranean diet: effects on blood pressureQ68910433
NADPH oxidase activity is required for endothelial cell proliferation and migrationQ73303463
Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart diseaseQ73708513
Ambient pressure upregulates nitric oxide synthase in a phosphorylated-extracellular regulated kinase- and protein kinase C-dependent mannerQ79349536
Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen speciesQ79827111
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylationQ22010150
Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitationsQ27026840
A new generation of Ca2+ indicators with greatly improved fluorescence propertiesQ27860793
Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt siteQ28363492
A synthetic inhibitor of the mitogen-activated protein kinase cascadeQ28367955
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionQ28378871
RETRACTED: Primary Prevention of Cardiovascular Disease with a Mediterranean DietQ29030043
Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxideQ29619956
A novel potent vasoconstrictor peptide produced by vascular endothelial cellsQ29620540
Antiflammin-2 prevents HL-60 adhesion to endothelial cells and prostanoid production induced by lipopolysaccharides.Q31963098
p38 mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor alpha-dependent pathway in response to black tea polyphenols.Q33947274
The diet and 15-year death rate in the seven countries studyQ34190297
Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidationQ34435166
Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trialQ34992452
Red wine polyphenols increase calcium in bovine aortic endothelial cells: a basis to elucidate signalling pathways leading to nitric oxide productionQ35044232
Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancerQ35059202
Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.Q35642646
Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospectsQ36924580
Hyperglycemia induces differential change in oxidative stress at gene expression and functional levels in HUVEC and HMVEC.Q37364547
Insulin resistance, lipotoxicity and endothelial dysfunctionQ37612301
Molecular mechanisms underlying the activation of eNOS.Q37655580
Endothelial dysfunction in diabetes: multiple targets for treatmentQ37711251
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.Q40034272
Endothelial function predicts future development of coronary artery disease: a study of women with chest pain and normal coronary angiogramsQ40511330
Critical evaluation of ECV304 as a human endothelial cell model defined by genetic analysis and functional responses: a comparison with the human bladder cancer derived epithelial cell line T24/83.Q40903073
The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor bindingQ41006169
Activation of endothelial nitric-oxide synthase by the p38 MAPK in response to black tea polyphenols.Q42466708
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivoQ42697165
PGE2 promotes Ca2+-mediated epithelial barrier disruption through EP1 and EP4 receptors in Caco-2 cell monolayersQ43059437
Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic miceQ43171566
Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health.Q43215240
Unsaturated free fatty acids inhibit Ca2+ mobilization and NO release in endothelial cells.Q43847992
Increased activity of endogenous endothelin in patients with type II diabetes mellitusQ44160794
P921main subjectfatty acidQ61476
olive oilQ93165
endotheliumQ111140
polyphenolQ290439
P304page(s)971-977
P577publication date2014-07-21
P1433published inRedox BiologyQ27724751
P1476titlePolyphenol fraction of extra virgin olive oil protects against endothelial dysfunction induced by high glucose and free fatty acids through modulation of nitric oxide and endothelin-1.
P478volume2

Reverse relations

cites work (P2860)
Q50284091A Mediterranean diet supplemented with extra virgin olive oil or nuts improves endothelial markers involved in blood pressure control in hypertensive women.
Q96305174A double-blind, placebo-controlled clinical trial to assess the effects of a combined nutraceutical on endothelial function in patients with mild-to-moderate hypercholesterolaemia
Q33634518A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL.
Q46635785Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats.
Q33838323C1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction
Q53818426Effects of Virgin Olive Oils Differing in Their Bioactive Compound Contents on Metabolic Syndrome and Endothelial Functional Risk Biomarkers in Healthy Adults: A Randomized Double-Blind Controlled Trial.
Q93382031Extra virgin olive oil: More than a healthy fat
Q55451059Hydroxytyrosol Ameliorates Endothelial Function under Inflammatory Conditions by Preventing Mitochondrial Dysfunction.
Q37729894Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders.
Q92258331Is Eating Raisins Healthy?
Q95856100Is Extra Virgin Olive Oil an Ally for Women's and Men's Cardiovascular Health?
Q60930299Maoberry (Antidesma bunius) ameliorates oxidative stress and inflammation in cardiac tissues of rats fed a high-fat diet
Q46264306Measuring the impact of olive pomace enriched biscuits on the gut microbiota and its metabolic activity in mildly hypercholesterolaemic subjects.
Q39295234Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials
Q57245567Phenolic Compounds Isolated from Olive Oil as Nutraceutical Tools for the Prevention and Management of Cancer and Cardiovascular Diseases
Q50439101Polyphenol-rich juices reduce blood pressure measures in a randomised controlled trial in high normal and hypertensive volunteers.
Q48275729Polyphenols and Oxidative Stress in Atherosclerosis-Related Ischemic Heart Disease and Stroke.
Q61812160Protective Role of Polyphenols against Vascular Inflammation, Aging and Cardiovascular Disease
Q50436812Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells.
Q61449928Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial
Q41147225Role of free fatty acids in endothelial dysfunction
Q92724210Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features
Q93079198The Mediterranean Diet, a Rich Source of Angiopreventive Compounds in Cancer
Q92504508The Use of Nutraceuticals to Counteract Atherosclerosis: The Role of the Notch Pathway
Q93079858Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018

Search more.