C1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction

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C1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS18061097
P932PMC publication ID5485929
P698PubMed publication ID28587104

P2093author name stringWeiwei Cai
Yuetao Zhou
Liying Qiu
Haijian Sun
Xuexue Zhu
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Endothelial FunctionQ61704068
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Inhibition of CTRP9, a novel and cardiac-abundantly expressed cell survival molecule, by TNFα-initiated oxidative signaling contributes to exacerbated cardiac injury in diabetic mice.Q64936967
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Knockdown of peroxisome proliferator-activated receptor gamma coactivator-1 alpha increased apoptosis of human endometrial cancer HEC-1A cellsQ37217612
C1q/tumor necrosis factor-related protein-9, a novel adipocyte-derived cytokine, attenuates adverse remodeling in the ischemic mouse heart via protein kinase A activationQ37299511
C1q/TNF-Related Protein 9 Protects Diabetic Rat Heart against Ischemia Reperfusion Injury: Role of Endoplasmic Reticulum StressQ37344976
Role of long non-coding RNA-RNCR3 in atherosclerosis-related vascular dysfunctionQ37482738
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Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activationQ38770370
C1q/TNF-related protein-9 inhibits cytokine-induced vascular inflammation and leukocyte adhesiveness via AMP-activated protein kinase activation in endothelial cellsQ38823002
Physiology and pathophysiology of oxLDL uptake by vascular wall cells in atherosclerosisQ38852365
CTRP9 enhances carotid plaque stability by reducing pro-inflammatory cytokines in macrophagesQ38907468
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Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrionQ39020249
Macrophages in vascular inflammation and atherosclerosisQ39123553
CTRP9 Ameliorates Pulmonary Arterial Hypertension Through Attenuating Inflammation and Improving Endothelial Cell Survival and FunctionQ40057877
Metformin improves endothelial function in aortic tissue and microvascular endothelial cells subjected to diabetic hyperglycaemic conditionsQ40431829
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligaseQ41014100
CTRP9 protein protects against myocardial injury following ischemia-reperfusion through AMP-activated protein kinase (AMPK)-dependent mechanismQ42000551
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme inductionQ42403314
PGC-1-related coactivator (PRC) negatively regulates endothelial adhesion of monocytes via inhibition of NF κB activityQ44830569
Long Noncoding RNA-GAS5: A Novel Regulator of Hypertension-Induced Vascular RemodelingQ45856499
Adipose-derived factor CTRP9 attenuates vascular smooth muscle cell proliferation and neointimal formationQ46240323
Metformin inhibits TNF-alpha-induced IkappaB kinase phosphorylation, IkappaB-alpha degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylationQ46504666
CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1α activationQ46526504
Salusin-β Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury via ROS/NFκB/MMP-9 PathwayQ46583570
Cinnamaldehyde prevents endothelial dysfunction induced by high glucose by activating Nrf2.Q46729636
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P577publication date2017-05-26
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleC1q/TNF-Related Protein-9 Ameliorates Ox-LDL-Induced Endothelial Dysfunction via PGC-1α/AMPK-Mediated Antioxidant Enzyme Induction
P478volume18

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cites work (P2860)
Q609529856-Gingerol Normalizes the Expression of Biomarkers Related to Hypertension via PPAR in HUVECs, HEK293, and Differentiated 3T3-L1 Cells
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Q99711260C1q/TNF-Related Protein 9 Promotes Revascularization in Response to Ischemia via an eNOS-Dependent Manner
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Q89896008The Role of PGC-1α and Mitochondrial Biogenesis in Kidney Diseases
Q64111698Vaccarin prevents ox-LDL-induced HUVEC EndMT, inflammation and apoptosis by suppressing ROS/p38 MAPK signaling

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