Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity

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Sirtuin-dependent epigenetic regulation in the maintenance of genome integrity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/FEBS.13053
P3181OpenCitations bibliographic resource ID4352899
P698PubMed publication ID25223884
P5875ResearchGate publication ID265646417

P50authorLaia Bosch-PreseguéQ57415722
P2093author name stringAlejandro Vaquero
P2860cites workDNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication fociQ22254582
Regulation of chromatin structure by site-specific histone H3 methyltransferasesQ24290115
Negative control of p53 by Sir2alpha promotes cell survival under stressQ24291828
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylaseQ24291829
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repressionQ24292887
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiationQ24293278
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylaseQ24293656
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activityQ24294017
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylaseQ24296766
Role of SIRT1 in homologous recombinationQ24297067
SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60Q24297333
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG IslandsQ24297794
Dynamic distribution of linker histone H1.5 in cellular differentiationQ24298254
The Polycomb group protein EZH2 directly controls DNA methylationQ24299020
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycleQ24299947
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formationQ24300487
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatinQ24306469
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylationQ24306868
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatinQ24310658
SUMOylation enhances DNA methyltransferase 1 activityQ24311725
Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuinsQ24312074
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox stateQ24312132
Epigenetic control of rDNA loci in response to intracellular energy statusQ24313528
A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infectionQ24313569
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1Q24314439
SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life spanQ24315083
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosisQ24322664
PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoliQ24329068
The human Rap1 protein complex and modulation of telomere lengthQ24337452
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1Q24337470
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosisQ24338619
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesQ24338663
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesisQ24540613
Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcriptionQ24545711
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcriptionQ24546024
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatinQ24561636
MicroRNA targeting specificity in mammals: determinants beyond seed pairingQ24607724
miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signalingQ24627398
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stabilityQ43068161
Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repairQ43217577
Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4.Q43796805
Sirt2 suppresses glioma cell growth through targeting NF-κB-miR-21 axisQ44729624
MiR-199a-5p promotes migration and tube formation of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and eNOS.Q45921109
A mechanism for coordinating chromatin modification and preinitiation complex assembly.Q45947044
Update CBP/p300 transgenic miceQ47945723
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrestQ48078984
SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampusQ48165385
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylationQ48300617
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stabilityQ48564987
The ACF1 complex is required for DNA double-strand break repair in human cells.Q50530840
Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2alpha.Q50730852
Inhibition of SIRT1 increases EZH2 protein level and enhances the repression of EZH2 on target gene expression.Q51547926
Targeting of MOF, a putative histone acetyl transferase, to the X chromosome of Drosophila melanogaster.Q52562207
Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila.Q52580421
Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes.Q52595108
MicroRNA-34a regulation of endothelial senescence.Q53312843
Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signalingQ39221344
Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125bQ39256723
SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60Q39348163
miR-520c and miR-373 upregulate MMP9 expression by targeting mTOR and SIRT1, and activate the Ras/Raf/MEK/Erk signaling pathway and NF-κB factor in human fibrosarcoma cellsQ39427500
Human SIRT1 associates with mitotic chromatin and contributes to chromosomal condensationQ39531475
miR-200a regulates SIRT1 expression and epithelial to mesenchymal transition (EMT)-like transformation in mammary epithelial cellsQ39539625
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination.Q39583815
Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cellsQ39622134
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stabilityQ39680313
MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cellsQ39726018
The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilonQ39733811
Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX.Q39778173
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1.Q39794127
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6.Q39821961
Histone H3-K56 acetylation is important for genomic stability in mammalsQ39857418
Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinomaQ39865449
Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.Q40053325
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.Q40102003
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damageQ40289662
PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosisQ41078460
DNA repair: PARP - another guardian angel?Q41680367
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissuesQ42017884
Isolation of microRNA targets by miRNP immunopurificationQ42530176
Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytesQ42535729
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.Q42672338
Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protectionQ42811651
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cellsQ29399636
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosisQ29547575
Histone acetyltransferasesQ29547823
Histone H4-K16 acetylation controls chromatin structure and protein interactionsQ29614521
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damageQ29614528
The DNA methyltransferases of mammalsQ29617317
Poly(ADP-ribose): novel functions for an old moleculeQ29617735
Functions of site-specific histone acetylation and deacetylationQ29617894
Transcriptional activation of miR-34a contributes to p53-mediated apoptosisQ29619556
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTRQ29619777
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient miceQ29619786
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stabilityQ29620365
miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cellsQ30176408
MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1.Q30421790
Genetic analysis of histone H4: essential role of lysines subject to reversible acetylationQ30452217
The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cellsQ30540850
The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylationQ31047769
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiaeQ33226323
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylationQ33238940
SirT1 regulates energy metabolism and response to caloric restriction in miceQ33323365
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repairQ33627986
The role of epigenetic transcription repression and DNA methyltransferases in cancer.Q33718270
SIRT6 promotes DNA repair under stress by activating PARP1Q33803766
Conformational dynamics of the chromatin fiber in solution: determinants, mechanisms, and functionsQ33958912
MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1Q33994431
miR-34a regulates mouse neural stem cell differentiationQ33998797
The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.Q34144213
Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription.Q34150869
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cellsQ34166536
Histone acetylation and deacetylation in yeastQ34187792
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disordersQ34351149
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sitesQ34359092
Characterization of lysine 56 of histone H3 as an acetylation site in Saccharomyces cerevisiaeQ34418079
A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response.Q34433751
Poly(ADP-ribosyl)ation: a posttranslational protein modification linked with genome protection and mammalian longevityQ34438715
PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeresQ34483600
Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cellsQ34500845
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiationQ24628741
ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESISQ24629431
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysineQ24631433
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcriptionQ24633178
Lysine acetylation: codified crosstalk with other posttranslational modificationsQ24644959
Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repressionQ24650557
miR-34a repression of SIRT1 regulates apoptosisQ24652720
SIRT6 in DNA repair, metabolism and ageingQ24653962
Histone H4 lysine 16 acetylation regulates cellular lifespanQ24657553
CBP/p300-mediated acetylation of histone H3 on lysine 56Q24657910
Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?Q24669960
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stressQ24670578
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-riboseQ24675630
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste proteinQ24682617
Predicting and validating microRNA targetsQ24801359
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cellsQ24810302
PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcriptionQ26823191
From sirtuin biology to human diseases: an updateQ27022606
Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaksQ27337186
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domainQ27860534
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegansQ27860584
Lysine acetylation targets protein complexes and co-regulates major cellular functionsQ27860589
The functions of animal microRNAsQ27860621
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylaseQ27860668
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assemblyQ27932260
Nuclear export modulates the cytoplasmic Sir2 homologue Hst2.Q27934693
Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.Q27935926
Acetylation in histone H3 globular domain regulates gene expression in yeast.Q27937002
The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation.Q27937957
Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosisQ27938401
Chromatin assembly factor 1 interacts with histone H3 methylated at lysine 79 in the processes of epigenetic silencing and DNA repairQ27939591
Role of histone H3 lysine 27 methylation in Polycomb-group silencingQ28131795
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteinsQ28139564
Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomesQ28141236
DNA methyltransferase Dnmt1 associates with histone deacetylase activityQ28141500
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteinsQ28187121
Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)atedQ28217564
Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not CenpcQ28221398
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancerQ28239595
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cellsQ28249223
Substrate and functional diversity of lysine acetylation revealed by a proteomics surveyQ28258445
MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1Q28261153
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATMQ28270543
p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammalsQ28286413
The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylationQ28286787
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouseQ28289637
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiationQ28294729
The SIRT2 deacetylase regulates autoacetylation of p300Q28300323
A microRNA component of the p53 tumour suppressor networkQ28305330
Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosisQ28507814
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6Q28509079
Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1Q28575665
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylationQ28586153
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 bindingQ28587228
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alphaQ28588941
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3Q28609869
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatinQ28647369
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouseQ34542060
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in miceQ34743879
MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cellsQ34773770
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone evictionQ34800325
miR-22 represses cancer progression by inducing cellular senescenceQ34825182
SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodelingQ34890876
MiR-34, SIRT1 and p53: the feedback loopQ34946471
Sorting out functions of sirtuins in cancerQ34970771
miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53.Q34991097
microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription.Q35006058
E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosisQ35015916
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and developmentQ35058520
MicroRNA-217 promotes angiogenesis of human cytomegalovirus-infected endothelial cells through downregulation of SIRT1 and FOXO3A.Q35078134
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survivalQ35080450
The constantly changing face of chromatinQ35170141
Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatinQ35348809
Regulation of Chromatin Structure and Gene Activity by Poly(ADP-Ribose) PolymerasesQ35570762
Histone H4 lysine 16 acetylation breaks the genome's silenceQ35605943
Poly(ADP-ribosyl)ated chromatin domains: access grantedQ35667074
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cellsQ35804659
Biochemistry and biology of mammalian DNA methyltransferasesQ35939026
Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cellsQ35990736
Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver diseaseQ35993416
Poly(ADP-ribosyl)ation and epigenetics. Is CTCF PARt of the plot?Q36012204
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.Q36102455
Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.Q36232699
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structureQ36297600
Histone modifications: signalling receptors and potential elements of a heritable epigenetic codeQ36406933
SIRT3 functions in the nucleus in the control of stress-related gene expressionQ36435193
Long-range histone acetylation: biological significance, structural implications, and mechanismsQ36579368
The histone methyltransferase SET8 is required for S-phase progressionQ36639133
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phaseQ36639143
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenanceQ36822706
Sirtuins: critical regulators at the crossroads between cancer and agingQ36908428
Glimpses of evolution: heterochromatic histone H3K9 methyltransferases left its marks behindQ36915186
Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1.Q36959668
MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regenerationQ37019204
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stressQ37038566
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant miceQ37097951
A miR-34a-SIRT6 axis in the squamous cell differentiation networkQ37101911
Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1.Q37118801
Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cellsQ37126117
Chromatin state marks cell-type- and gender-specific replication of the Drosophila genomeQ37135175
Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse developmentQ37145387
Sirtuins in neurodegenerative diseases: an update on potential mechanisms.Q37196388
HIS-24 linker histone and SIR-2.1 deacetylase induce H3K27me3 in the Caenorhabditis elegans germ lineQ37233422
The role of poly(ADP-ribosyl)ation in epigenetic events.Q37262429
MicroRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1.Q37296879
A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma bruceiQ37367700
The conserved role of sirtuins in chromatin regulationQ37451075
SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphomaQ37583497
A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausingQ37635773
The dual role of sirtuins in cancerQ37937462
Chromatin and the genome integrity network.Q38068091
Sirtuins in stress response: guardians of the genome.Q38133369
Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivityQ38326372
miR-195 regulates SIRT1-mediated changes in diabetic retinopathy.Q39020818
SIRT1 knockdown promotes neural differentiation and attenuates the heat shock response.Q39033591
Hsa-miR-125b suppresses bladder cancer development by down-regulating oncogene SIRT7 and oncogenic long non-coding RNA MALAT1.Q39036862
Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer.Q39078249
MicroRNA-126 inhibits osteosarcoma cells proliferation by targeting Sirt1.Q39121751
Repression of SIRT1 promotes the differentiation of mouse induced pluripotent stem cells into neural stem cellsQ39191792
Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repairQ39208600
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1745-1767
P577publication date2014-10-13
P1433published inFEBS JournalQ1388041
P1476titleSirtuin-dependent epigenetic regulation in the maintenance of genome integrity
P478volume282

Reverse relations

cites work (P2860)
Q58093768Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer
Q49990454Canonical and Noncanonical Actions of Arabidopsis Histone Deacetylases in Ribosomal RNA Processing
Q42358713Capsaicin reactivates hMOF in gastric cancer cells and induces cell growth inhibition
Q39036105Could Sirtuin Activities Modify ALS Onset and Progression?
Q58696997Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress
Q28080288Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells
Q28076508Dissecting bipolar disorder complexity through epigenomic approach
Q92627860Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis progression
Q95592009Epigenetics and depression
Q55366214Fission Yeast Sirtuin Hst4 Functions in Preserving Genomic Integrity by Regulating Replisome Component Mcl1.
Q28081001Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious Diseases
Q51092697Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis.
Q50106782LC-MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes
Q61688093Liver Diseases: Epigenetic Mechanisms, Oxidative Stress and Use of Alpha-Lipoic Acid
Q47665764Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development
Q92644256Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure
Q96303645PWR/HDA9/ABI4 Complex Epigenetically Regulates ABA Dependent Drought Stress Tolerance in Arabidopsis
Q90608246Preconception Exposure to Fine Particulate Matter Leads to Cardiac Dysfunction in Adult Male Offspring
Q38747012SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms
Q91297787SIRT1 in forebrain excitatory neurons produces sexually dimorphic effects on depression-related behaviors and modulates neuronal excitability and synaptic transmission in the medial prefrontal cortex
Q40349749SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation
Q62493122Scientometric Analysis of SIRT6 Studies
Q42601540Second German-Catalan workshop on epigenetics & cancer
Q42263658Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1.
Q34555201Sirtuins and DNA damage repair: SIRT7 comes to play
Q57188568Special Issue: Epigenetics
Q26746231The world of protein acetylation
Q38866428Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells