scholarly article | Q13442814 |
P50 | author | Maud Gratuze | Q59195478 |
P2093 | author name string | Alexis Bretteville | |
Anastasia Noël | |||
Emmanuel Planel | |||
Franck R Petry | |||
François Marcouiller | |||
Françoise Morin | |||
Geoffrey Truchetti | |||
Isabelle Poitras | |||
Kevin Wong | |||
László Virág | |||
Marie-Amélie Papon | |||
Noura El Khoury | |||
Robert A Whittington | |||
P2860 | cites work | Tau pathology in Alzheimer disease and other tauopathies | Q22252520 |
Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments | Q24599152 | ||
Measurement of protein using bicinchoninic acid | Q26778491 | ||
The effects of increasing plasma concentrations of dexmedetomidine in humans | Q28141747 | ||
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects | Q28205334 | ||
Propofol directly increases tau phosphorylation | Q28477036 | ||
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease | Q28478380 | ||
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology | Q29617284 | ||
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease | Q29617286 | ||
Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease | Q30438119 | ||
Anesthesia induces phosphorylation of tau | Q33691128 | ||
A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis | Q33720044 | ||
Stress-induced tau phosphorylation: functional neuroplasticity or neuronal vulnerability? | Q34003380 | ||
Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment | Q34198357 | ||
Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist. | Q34481160 | ||
Alzheimer's disease and anesthesia | Q34554509 | ||
Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics | Q34577164 | ||
The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies | Q34587678 | ||
Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice | Q35026932 | ||
Role of serine/threonine protein phosphatase in Alzheimer's disease | Q35059545 | ||
Recognition of the minimal epitope of monoclonal antibody Tau‐1 depends upon the presence of a phosphate group but not its location | Q72073020 | ||
Lack in effects of therapeutic concentrations of dexmedetomidine and clonidine on the neuromuscular blocking action of rocuronium in isolated rat diaphragms | Q80210706 | ||
Role of tau protein in both physiological and pathological conditions. | Q35715199 | ||
Paired helical filament tau in Alzheimer's disease. The kinase connection | Q35833298 | ||
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development | Q36335067 | ||
β2 adrenergic receptor, protein kinase A (PKA) and c-Jun N-terminal kinase (JNK) signaling pathways mediate tau pathology in Alzheimer disease models | Q36760275 | ||
Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo | Q37029878 | ||
Anesthesia and tau pathology | Q37089765 | ||
Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: a retrospective case report series | Q37159524 | ||
Tau aggregates: toxic, inert, or protective species? | Q37238290 | ||
Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia | Q37280755 | ||
Biochemical isolation of insoluble tau in transgenic mouse models of tauopathies | Q38004969 | ||
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial | Q38383872 | ||
Pharmacokinetic implications for the clinical use of propofol | Q38722656 | ||
c-jun N-terminal kinase hyperphosphorylates R406W tau at the PHF-1 site during mitosis | Q39512404 | ||
Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A. | Q39967325 | ||
Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat | Q40232008 | ||
The effects of dexmedetomidine on neuromuscular blockade in human volunteers | Q41612261 | ||
Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury. | Q42142119 | ||
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein | Q42827866 | ||
Dexmedetomidine in the care of critically ill patients from 2001 to 2007: an observational cohort study | Q42976771 | ||
Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST). | Q43106418 | ||
Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain | Q43225217 | ||
Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis. | Q44210287 | ||
Phosphorylated serine 199 of microtubule-associated protein tau is a neuronal epitope abundantly expressed in youth and an early marker of tau pathology | Q44283795 | ||
Interaction of the alpha-2 adrenergic- and opioid receptor with the cGMP system in the mouse cerebellum | Q44350628 | ||
Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex | Q44491452 | ||
Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment. | Q45195626 | ||
A hypnotic response to dexmedetomidine, an alpha 2 agonist, is mediated in the locus coeruleus in rats | Q46023890 | ||
Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes | Q46041432 | ||
Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau | Q46127208 | ||
Differential effects of alpha 2-adrenoceptors in the modulation of the thermoregulatory response in mice induced by meperidine | Q46518888 | ||
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. | Q46522758 | ||
Dexmedetomidine increases hippocampal phosphorylated extracellular signal-regulated protein kinase 1 and 2 content by an alpha 2-adrenoceptor-independent mechanism: evidence for the involvement of imidazoline I1 receptors | Q46739677 | ||
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. | Q48232865 | ||
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms | Q48254354 | ||
Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration | Q48255703 | ||
Evaluation of spatial memory of C57BL/6J and CD1 mice in the Barnes maze, the Multiple T-maze and in the Morris water maze | Q48313979 | ||
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments | Q48344680 | ||
Plaques, tangles and dementia. A quantitative study | Q48874775 | ||
Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. | Q53199978 | ||
Conformational change as one of the earliest alterations of tau in Alzheimer's disease. | Q53238045 | ||
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. | Q53246695 | ||
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205. | Q54613756 | ||
Rapid Tau Protein Dephosphorylation and Differential Rephosphorylation during Cardiac Arrest-Induced Cerebral Ischemia and Reperfusion | Q57897037 | ||
P4510 | describes a project that uses | ImageQuant | Q112270642 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
dexmedetomidine | Q412133 | ||
P304 | page(s) | 2414-2428 | |
P577 | publication date | 2015-05-09 | |
P1433 | published in | Neurobiology of Aging | Q7002141 |
P1476 | title | Dexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro | |
P478 | volume | 36 |
Q90218549 | Administration of the benzodiazepine midazolam increases tau phosphorylation in the mouse brain |
Q47651365 | Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6. |
Q37733003 | Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels |
Q64107948 | Lasting effects of general anesthetics on the brain in the young and elderly: "mixed picture" of neurotoxicity, neuroprotection and cognitive impairment |
Q38983421 | Lasting impact of general anaesthesia on the brain: mechanisms and relevance |
Q47420946 | Protein phosphatase 2A and tau: an orchestrated 'Pas de Deux'. |
Q61814347 | The Role of Neuroinflammation in Postoperative Cognitive Dysfunction: Moving From Hypothesis to Treatment |
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