Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau

scientific article published on August 11, 1995

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.270.32.18917
P953full work available at URLhttp://www.jbc.org/article/S0021925818519256/pdf
https://api.elsevier.com/content/article/PII:S0021925818519256?httpAccept=text/xml
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https://syndication.highwire.org/content/doi/10.1074/jbc.270.32.18917
P698PubMed publication ID7642549
P5875ResearchGate publication ID247481320

P50authorJohn Q. TrojanowskiQ6253636
P2093author name stringM. Goedert
I. Lieberburg
G. V. Johnson
R. Jakes
R. Barbour
D. Schenk
J. M. Litersky
P. Seubert
M. Mawal-Dewan
P2860cites workThe carboxyl third of tau is tightly bound to paired helical filaments.Q53186869
Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.Q53199978
Proline-directed and non-proline-directed phosphorylation of PHF-tau.Q53203171
A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.Q53296439
Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.Q54613756
p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's diseaseQ55920639
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5Q60603655
Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tauQ72901527
A protein factor essential for microtubule assemblyQ22010837
Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tauQ24648590
Continuous cultures of fused cells secreting antibody of predefined specificityQ26776979
Measurement of protein using bicinchoninic acidQ26778491
Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's diseaseQ28910345
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer diseaseQ33582860
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.Q34324670
A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubuleQ34345777
Tau protein function in living cellsQ36216609
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during developmentQ36335067
Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitroQ36531639
Tau protein and the neurofibrillary pathology of Alzheimer's diseaseQ40386025
Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementiasQ40794805
Phosphorylation of microtubule-associated protein tau: identification of the site for Ca2(+)-calmodulin dependent kinase and relationship with tau phosphorylation in Alzheimer tangles.Q41229492
Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.Q41585811
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau proteinQ42827866
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's diseaseQ43423232
Distribution of tau proteins in the normal human central and peripheral nervous systemQ44921131
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.Q48253590
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule bindingQ48277664
Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.Q48394153
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinaseQ48406074
Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's diseaseQ48444661
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoformsQ48571996
Epitopes that span the tau molecule are shared with paired helical filaments.Q53186865
P433issue32
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P1104number of pages6
P304page(s)18917-18922
P577publication date1995-08-01
1995-08-11
P1433published inJournal of Biological ChemistryQ867727
P1476titleDetection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau
P478volume270

Reverse relations

cites work (P2860)
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