In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3beta in neuronal apoptosis: links to tau phosphorylation.

scientific article published in February 2002

In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3beta in neuronal apoptosis: links to tau phosphorylation. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1046/J.1460-9568.2002.01899.X
P698PubMed publication ID11886446

P50authorFaraj TerroQ59685281
P2093author name stringJ Hugon
N S Wong
W Elyaman
P2860cites workMitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylationQ24528506
Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegenerationQ24530141
Lamin proteolysis facilitates nuclear events during apoptosisQ24681695
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase BQ27860731
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activationQ28140761
Tau protein is hyperphosphorylated in a site-specific manner in apoptotic neuronal PC12 cellsQ30962853
Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic miceQ33180485
Toxic neuronal apoptosis and modifications of tau and APP gene and protein expressionsQ33719823
Presenilins and Alzheimer's disease: biological functions and pathogenic mechanismsQ33835683
Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.Q34442292
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic miceQ34449486
Apoptosis in the developing CNS.Q36808251
Modifications of neuronal phosphorylated tau immunoreactivity induced by NMDA toxicityQ36860250
Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degenerationQ37273048
Tau protein and the neurofibrillary pathology of Alzheimer's diseaseQ40386025
Tau domains, phosphorylation, and interactions with microtubules.Q40416733
Tyrosine dephosphorylation of glycogen synthase kinase-3 is involved in its extracellular signal-dependent inactivationQ41173454
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.Q41423732
Modulation of tau phosphorylation and intracellular localization by cellular stressQ41809018
Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithiumQ42484847
Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament TauQ46127208
The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylationQ47252107
Brefeldin A-induced apoptosis is expressed in rat neurons with dephosphorylated tau protein.Q47719985
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathwayQ47762057
Glutamate increases tau phosphorylation in primary neuronal cultures from fetal rat cerebral cortex.Q48122748
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule bindingQ48277664
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brainQ48317594
Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A.Q48482683
Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.Q48622377
Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neuronsQ48658321
Cultured neurons expressing phosphorylated tau are more resistant to apoptosis induced by NMDA or serum deprivationQ48747792
Evidence for apoptotic cell death in Alzheimer's disease.Q53200058
Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation.Q53233594
Binding specificity of monoclonal antibody AD2: influence of the phosphorylation state of tau.Q53236376
Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.Q53237934
Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.Q54415298
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)651-660
P577publication date2002-02-01
P1433published inEuropean Journal of NeuroscienceQ5412733
P1476titleIn vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3beta in neuronal apoptosis: links to tau phosphorylation
P478volume15