Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring

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Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...990335C
P356DOI10.1371/JOURNAL.PONE.0090335
P3181OpenCitations bibliographic resource ID1319893
P932PMC publication ID3940881
P698PubMed publication ID24594983
P5875ResearchGate publication ID260526930

P50authorJames HesterQ56385883
Matthew V CannonQ56518157
David A. BuchnerQ42512672
P2093author name stringDavid Serre
Joseph H Nadeau
Ephraim Sehayek
Hadley Miller
P2860cites workREV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasisQ21145813
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysisQ24310555
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specificQ24656230
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genesQ24683425
VAMPIRE microarray suite: a web-based platform for the interpretation of gene expression dataQ24812937
edgeR: a Bioconductor package for differential expression analysis of digital gene expression dataQ27860819
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factorQ28238069
Gender-specific methylation differences in relation to prenatal exposure to cigarette smokeQ28396952
Stability and flexibility of epigenetic gene regulation in mammalian developmentQ29615922
Genetic dissection of complex traits with chromosome substitution strains of mice.Q51005457
Prenatal and perinatal influences on long-term psychomotor development in offspring of diabetic mothers.Q51035672
Glucose tolerance and insulin secretion in children of mothers with pregestational IDDM or gestational diabetes.Q51573631
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression.Q51610482
Overweight and obesity in infants of mothers with long-term insulin-dependent diabetes or gestational diabetesQ73435768
Role of the prenatal environment in the development of obesityQ74591025
Gestational obesity accentuates obesity in obesity-prone progenyQ77358986
Epigenetics: a landscape takes shapeQ29616623
A maternal "junk food" diet in pregnancy and lactation promotes nonalcoholic Fatty liver disease in rat offspringQ33772350
Season of conception in rural gambia affects DNA methylation at putative human metastable epiallelesQ33784616
Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats.Q33832558
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profilingQ33848902
Offspring of mothers fed a high fat diet display hepatic cell cycle inhibition and associated changes in gene expression and DNA methylation.Q33968085
Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy.Q34237448
Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitusQ34399314
Diabetes and obesity: the twin epidemicsQ34482313
Childhood obesity and metabolic imprinting: the ongoing effects of maternal hyperglycemiaQ34630906
Prenatal exposure to the Dutch famine and disease in later life: an overviewQ36127666
The juxtaparanodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity.Q36833907
Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liverQ36973423
Genetic architecture of complex traits: large phenotypic effects and pervasive epistasisQ37018913
High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 miceQ37061691
Prenatal stress or high-fat diet increases susceptibility to diet-induced obesity in rat offspringQ37163551
Interrelationship between liver X receptor alpha, sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor gamma, and small heterodimer partner in the transcriptional regulation of glucokinase gene expression in liverQ37200875
Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17.Q37319313
Prenatal exposure to undernutrition and programming of responses to high-fat feeding in the rat.Q37389108
MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genomeQ39776070
Maternal nutrition, fetal nutrition, and disease in later lifeQ41588886
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.Q41836564
Maternal high fat feeding and gestational dietary restriction: effects on offspring body weight, food intake and hypothalamic gene expression over three generations in miceQ43080005
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LQ44429399
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspringQ46522809
Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expressionQ46813713
Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance: a novel murine model of developmental programmingQ46845260
Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 yearsQ47311562
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesedgeRQ113334690
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectDNA methylationQ874745
P304page(s)e90335
P577publication date2014-01-01
P1433published inPLOS OneQ564954
P1476titleMaternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring
P478volume9

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cites work (P2860)
Q92537636A Maternal High-Fat Diet Induces DNA Methylation Changes That Contribute to Glucose Intolerance in Offspring
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Q47102227Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice
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Q41692185Enhanced Steatosis and Fibrosis in Liver of Adult Offspring Exposed to Maternal High-Fat Diet
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Q50595938Global DNA methylation was changed by a maternal high-lipid, high-energy diet during gestation and lactation in male adult mice liver.
Q34988941Influences of gestational obesity on associations between genotypes and gene expression levels in offspring following maternal gastrointestinal bypass surgery for obesity
Q34463218Lifestyle, pregnancy and epigenetic effects
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Q48578711Maternal obesity heritably perturbs offspring metabolism for three generations without serial programming.
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Q64254417The Impact of Caloric Restriction on the Epigenetic Signatures of Aging
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