Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

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Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis is …
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scholarly articleQ13442814

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P819ADS bibcode2016NatCo...710973L
P6179Dimensions Publication ID1029311390
P356DOI10.1038/NCOMMS10973
P3181OpenCitations bibliographic resource ID386992
P932PMC publication ID4793047
P698PubMed publication ID26964500
P5875ResearchGate publication ID297898391

P50authorMarkus NeurathQ1750078
Mona Hc BiermannQ86024317
Dane WildnerQ87436061
Claudia GüntherQ87592173
Andrew L CroxfordQ96199646
Moritz LeppkesQ114563631
Sebastian HirthQ114563633
Ulrike BillmeierQ114563642
Christian MaueröderQ56989578
Julia MayerleQ65559556
Markus M LerchQ38327735
Markus HoffmannQ38799638
Stefan WirtzQ40333699
Ari WaismanQ41560798
Luis E MunozQ42401257
P2093author name stringChristoph Becker
Veit Krenn
Dieter E Jenne
Georg Schett
Martin Herrmann
Kerri Mowen
Susanne Paulus
Stefanie Nowecki
P2860cites workImpairment of neutrophil extracellular trap degradation is associated with lupus nephritisQ24606320
Extracellular DNA traps promote thrombosis.Q24613579
The pancreatic stellate cell: a star on the rise in pancreatic diseasesQ24676727
Neutrophil extracellular traps kill bacteriaQ27860996
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasisQ28238414
Structural basis for Ca(2+)-induced activation of human PAD4Q28271512
Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastaseQ28533695
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosisQ28588383
Neutrophils and immunity: challenges and opportunitiesQ29617616
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.Q30436326
Bioluminescence imaging of myeloperoxidase activity in vivoQ33700977
Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasiaQ33810570
PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infectionQ33968227
GP2, the homologue to the renal cast protein uromodulin, is a major component of intraductal plugs in chronic pancreatitisQ34110248
Chronic pancreatitis: diagnosis, classification, and new genetic developmentsQ34141293
Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2.Q34393801
Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular trapsQ34412346
A mouse model of autoimmune pancreatitis with salivary gland involvement triggered by innate immunity via persistent exposure to avirulent bacteriaQ84792924
Acute cholangitis in association with acute pancreatitis: incidence, clinical features and outcome in relation to ERCP and endoscopic sphincterotomyQ50174150
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.Q50715057
Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines.Q51726697
TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice.Q54419758
Acute pancreatitisQ56094875
Chronic pancreatitisQ56627343
Role of neutrophils in the activation of trypsinogen in severe acute pancreatitisQ57554628
In vitro activation of pro-cathepsin B by three serine proteinases: leucocyte elastase, cathepsin G, and the urokinase-type plasminogen activatorQ70494598
Early ductal decompression prevents the progression of biliary pancreatitis: an experimental study in the opossumQ70767676
The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injuryQ74463023
PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shockQ35197441
Interleukin-17: the missing link between T-cell accumulation and effector cell actions in rheumatoid arthritis?Q35675887
Association of cathepsin B gene polymorphisms with tropical calcific pancreatitisQ35768923
A mouse model of acute biliary pancreatitis induced by retrograde pancreatic duct infusion of Na-taurocholateQ36172703
Ly6G ligation blocks recruitment of neutrophils via a β2-integrin-dependent mechanismQ36177942
Protein arginine deiminase 4: evidence for a reverse protonation mechanismQ36402001
Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitisQ36471402
IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethalityQ36638151
Inflammation. Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosisQ36862166
IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in miceQ37036086
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.Q37124853
Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitisQ37253687
Lactoferrin in chronic pancreatitis.Q37489318
Autoimmune pancreatitis: the clinicopathological characteristics of the subtype with granulocytic epithelial lesionsQ37765184
Calcium carbonate saturation in human pancreatic juice: possible role of ductal H+ secretionQ39020982
Protein content of precipitates present in pancreatic juice of alcoholic subjects and patients with chronic calcifying pancreatitisQ39038118
Bicarbonate and Cyclic Amp Content of Pure Human Pancreatic Juice in Response to Graded Doses of Synthetic SecretinQ39979008
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitisQ40735691
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute PancreatitisQ41036171
Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosisQ41945735
In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.Q42003082
Advances in the etiology of chronic pancreatitis.Q42918806
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitisQ43634098
Inflammatory rather than infectious insults play a role in exocrine tissue damage in a mouse model for coxsackievirus B4-induced pancreatitisQ43856371
Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitisQ43997200
Tissue-specific and inducible Cre-mediated recombination in the gut epitheliumQ44999476
Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in miceQ45056690
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.Q46257713
Biliary Sludge as a Cause of Acute PancreatitisQ50149107
Occult microlithiasis in 'idiopathic' acute pancreatitis: prevention of relapses by cholecystectomy or ursodeoxycholic acid therapyQ50151393
Activation of human neutrophils by calcium carbonate polymorphsQ50158658
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)10973
P577publication date2016-03-11
P1433published inNature CommunicationsQ573880
P1476titleExternalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
P478volume7

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cites work (P2860)
Q91810906"In sickness and in health" - how neutrophil extracellular trap (NET) works in infections, selected diseases and pregnancy
Q54957959A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution.
Q48193835A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils.
Q91286813Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis
Q49239288Alkaline pH Promotes NADPH Oxidase-Independent Neutrophil Extracellular Trap Formation: A Matter of Mitochondrial Reactive Oxygen Species Generation and Citrullination and Cleavage of Histone
Q46828081Autophagy, Inflammation, and Immune Dysfunction in the Pathogenesis of Pancreatitis.
Q52670884Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis.
Q45991735Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.
Q89947757Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
Q52606228DNA Area and NETosis Analysis (DANA): a High-Throughput Method to Quantify Neutrophil Extracellular Traps in Fluorescent Microscope Images.
Q42224190Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma
Q38656177Do Animal Models of Acute Pancreatitis Reproduce Human Disease?
Q30827538Elevated homocysteine levels in type 2 diabetes induce constitutive neutrophil extracellular traps.
Q61810271Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine
Q38908166Extracellular Acidification Inhibits the ROS-Dependent Formation of Neutrophil Extracellular Traps
Q92860794Extracellular DNA traps in inflammation, injury and healing
Q97692645Extracellular cold-inducible RNA-binding protein regulates neutrophil extracellular trap formation and tissue damage in acute pancreatitis
Q47035971Host DNases prevent vascular occlusion by neutrophil extracellular traps
Q42024223Human Amniotic Membrane Mesenchymal Stem Cells inhibit Neutrophil Extracellular Traps through TSG-6.
Q26742159Inhibitors of Serine Proteases in Regulating the Production and Function of Neutrophil Extracellular Traps
Q64103676Insight into Neutrophil Extracellular Traps through Systematic Evaluation of Citrullination and Peptidylarginine Deiminases
Q57073728Low-Dose Radiotherapy Ameliorates Advanced Arthritis in hTNF-α tg Mice by Particularly Positively Impacting on Bone Metabolism
Q48193665Missing in action-The meaning of cell death in tissue damage and inflammation.
Q30831357Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs
Q37043270NET Confusion
Q38998709NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils
Q34540730Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation
Q37323729Neutrophil Extracellular Traps Form a Barrier between Necrotic and Viable Areas in Acute Abdominal Inflammation
Q57213795Neutrophil Extracellular Traps Formation and Aggregation Orchestrate Induction and Resolution of Sterile Crystal-Mediated Inflammation
Q28075970Neutrophil Extracellular Traps Go Viral
Q99708854Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones
Q98288408Neutrophil Extracellular Traps: Signaling Properties and Disease Relevance
Q49485640Neutrophil extracellular traps in immunity and disease
Q52668399Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types?
Q49570630Neutrophils and neutrophil extracellular traps in the liver and gastrointestinal system
Q38900762New insights into the pathways initiating and driving pancreatitis.
Q91623113Organ Failure Due to Systemic Injury in Acute Pancreatitis
Q30830302Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation
Q89096112Pancreatitis: NETs clog pancreatic ducts
Q49319636Perspective on Protein Arginine Deiminase Activity-Bicarbonate Is a pH-Independent Regulator of Citrullination
Q61811115Progression on Citrullination of Proteins in Gastrointestinal Cancers
Q93048356Reduced Anti-Histone Antibodies and Increased Risk of Rheumatoid Arthritis Associated with a Single Nucleotide Polymorphism in PADI4 in North Americans
Q50331019Regulating NETosis: Increasing pH Promotes NADPH Oxidase-Dependent NETosis
Q92223551SP-D attenuates LPS-induced formation of human neutrophil extracellular traps (NETs), protecting pulmonary surfactant inactivation by NETs
Q91957886Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants
Q37690857The Interplay between Inflammation, Coagulation and Endothelial Injury in the Early Phase of Acute Pancreatitis: Clinical Implications.
Q52668322The Neutrophil's Choice: Phagocytose vs Make Neutrophil Extracellular Traps.
Q90950007To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps
Q55318481Two-in-one: UV radiation simultaneously induces apoptosis and NETosis.
Q98194499Vascular occlusion by neutrophil extracellular traps in COVID-19

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