| scholarly article | Q13442814 |
| P50 | author | Markus M Lerch | Q38327735 |
| Wolfram Domschke | Q52767669 | ||
| P2093 | author name string | W Roth | |
| C Peters | |||
| T Reinheckel | |||
| J Deussing | |||
| H Lippert | |||
| B Brandt-Nedelev | |||
| M Ruthenbuerger | |||
| W Halangk | |||
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| The effect of chloroquine administration on two experimental models of acute pancreatitis. | Q41937542 | ||
| Multiple forms of β-glucuronidase in rat liver lysosomes and microsomes | Q41982681 | ||
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| Possible lysosomal activation of pancreatic zymogens. Activation of both human trypsinogens by cathepsin B and spontaneous acid. Activation of human trypsinogen 1 | Q67988505 | ||
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| Edema and intrapancreatic trypsinogen activation precede glutathione depletion during caerulein pancreatitis | Q71404575 | ||
| Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis | Q71569118 | ||
| Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B | Q73475948 | ||
| Inhibition of cathepsin B does not affect the intracellular activation of trypsinogen by cerulein hyperstimulation in isolated rat pancreatic acinar cells | Q74070131 | ||
| Early trypsinogen activation in acute pancreatitis | Q74463032 | ||
| Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats | Q74831729 | ||
| Codistribution of TAP and the granule membrane protein GRAMP-92 in rat caerulein-induced pancreatitis | Q77551309 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 773-781 | |
| P577 | publication date | 2000-09-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis | |
| P478 | volume | 106 |
| Q35683586 | 6. Cathepsin K inhibitors: their potential as anti-osteoporosis agents |
| Q47113213 | A Mini-Review on the Effect of Docosahexaenoic Acid (DHA) on Cerulein-Induced and Hypertriglyceridemic Acute Pancreatitis |
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| Q42238474 | ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis |
| Q30356472 | Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis. |
| Q91286813 | Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis |
| Q43154771 | Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation |
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| Q38938667 | Acute acinar pancreatitis blocks vesicle-associated membrane protein 8 (VAMP8)-dependent secretion, resulting in intracellular trypsin accumulation. |
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| Q35801819 | Acute pancreatitis and organ failure: pathophysiology, natural history, and management strategies. |
| Q27008383 | Acute pancreatitis in children and adolescents |
| Q35144937 | Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice |
| Q44630545 | Alcohol and Zymogen Activation in the Pancreatic Acinar Cell |
| Q42039256 | Analysis of substrate specificity and endopeptidyl activities of the cathepsin B-like proteinase from Helicoverpa armigera. |
| Q38164699 | Animal models of pancreatitis: can it be translated to human pain study? |
| Q54581967 | Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. |
| Q40569580 | Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents |
| Q35768923 | Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis |
| Q36454316 | Autophagy and pancreatitis |
| Q51022472 | Autophagy in pancreatic acinar cells in caerulein-treated mice: immunolocalization of related proteins and their potential as markers of pancreatitis. |
| Q95840706 | BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux |
| Q33479201 | Bioactive substances produced by marine isolates of Pseudomonas |
| Q24675973 | Biochemical models of hereditary pancreatitis |
| Q36414170 | Biochemistry and clinical role of trypsinogens and pancreatic secretory trypsin inhibitor |
| Q44219923 | CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells |
| Q92917206 | CaMKII/proteasome/cytosolic calcium/cathepsin B axis was present in tryspin activation induced by nicardipine |
| Q46438296 | Caerulein or taurocholate induced enzymatic and histologic alterations in the isolated perfused rat pancreas |
| Q28591507 | Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca2+ release through IP3 receptors |
| Q36509878 | Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation |
| Q34511122 | Cathepsin B & L are not required for ebola virus replication |
| Q41862502 | Cathepsin B Activity Initiates Apoptosis via Digestive Protease Activation in Pancreatic Acinar Cells and Experimental Pancreatitis. |
| Q28274479 | Cathepsin B Expression and the Correlation with Clinical Aspects of Oral Squamous Cell Carcinoma |
| Q78234621 | Cathepsin B Inhibitory Tetraene Lactones from the FungusTalaromyces wortmannii |
| Q38735425 | Cathepsin B as a potential cystatin M/E target in the mouse hair follicle. |
| Q24797108 | Cathepsin B cleavage of the trypsinogen activation peptide |
| Q42410004 | Cathepsin B gene polymorphism Val26 is not associated with idiopathic chronic pancreatitis in European patients |
| Q28543230 | Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection |
| Q26782938 | Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate |
| Q28365734 | Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications |
| Q28573039 | Cathepsin B localizes to plasma membrane caveolae of differentiating myoblasts and is secreted in an active form at physiological pH |
| Q44107311 | Cathepsin B mediates tumor necrosis factor-induced arachidonic acid release in tumor cells |
| Q37272093 | Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. |
| Q42102273 | Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells |
| Q45991735 | Cathepsin B-mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice. |
| Q41230243 | Cathepsin B: Basis Sequence: Mouse |
| Q37362547 | Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. |
| Q47305008 | Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis. |
| Q40734800 | Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells |
| Q42273053 | Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice. |
| Q44904231 | Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy |
| Q39663804 | Cathepsin X-deficient gastric epithelial cells in co-culture with macrophages: characterization of cytokine response and migration capability after Helicobacter pylori infection |
| Q36685124 | Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants |
| Q26801387 | Central role of neutrophil in the pathogenesis of severe acute pancreatitis |
| Q37591305 | Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice |
| Q34229273 | Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription |
| Q90750780 | Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice |
| Q42726070 | Co-localization hypothesis: a mechanism for the intrapancreatic activation of digestive enzymes during the early phases of acute pancreatitis |
| Q36480910 | Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer |
| Q36030187 | Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis |
| Q38988021 | Complement in Pancreatic Disease-Perpetrator or Savior? |
| Q38644547 | Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response |
| Q46940185 | Cysteine cathepsins are not involved in Fas/CD95 signalling in primary skin fibroblasts |
| Q38162775 | Cysteine cathepsins in neurological disorders |
| Q36708304 | Cysteine cathepsins: regulators of antitumour immune response |
| Q91690107 | Cysteine-type cathepsins promote the effector phase of acute cutaneous delayed-type hypersensitivity reactions |
| Q40242719 | Cytotoxic T lymphocytes from cathepsin B-deficient mice survive normally in vitro and in vivo after encountering and killing target cells |
| Q33994773 | Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice |
| Q28283899 | Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome) |
| Q93222396 | Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin |
| Q38701894 | Deficiency of filaggrin regulates endogenous cysteine protease activity, leading to impaired skin barrier function |
| Q41462476 | Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome. |
| Q83428006 | Diabetes aggravates acute pancreatitis and inhibits pancreas regeneration in mice |
| Q43146280 | Digesting new information about the role of trypsin in pancreatitis |
| Q42391679 | Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis. |
| Q34194342 | Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L. |
| Q34471105 | Distinct roles for cysteine cathepsin genes in multistage tumorigenesis |
| Q35992375 | Distinctive roles of unsaturated and saturated fatty acids in hyperlipidemic pancreatitis |
| Q33750485 | Do molecular signals from the conceptus influence endometrium decidualization in rodents? |
| Q48265031 | Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway |
| Q44274590 | Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction |
| Q36310514 | Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells |
| Q42868257 | Emergent therapy with therapeutic plasma exchange in acute recurrent pancreatitis due to severe hypertriglyceridemia |
| Q34283421 | Endoplasmic reticulum stress is chronically activated in chronic pancreatitis |
| Q44764161 | Endothelial nitric oxide synthase is protective in the initiation of caerulein-induced acute pancreatitis in mice |
| Q93000610 | Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B |
| Q36190500 | Evaluation of serum cathepsin B and D in relation to clinicopathological staging of colorectal cancer |
| Q44020802 | Evolution of placentally expressed cathepsins |
| Q27324281 | Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis |
| Q35187211 | Family C1 cysteine proteases: biological diversity or redundancy? |
| Q44716045 | Fas deficiency exacerbates cerulein-induced pancreatitis |
| Q46901983 | Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis |
| Q41966158 | Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen |
| Q39819247 | Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis |
| Q37208470 | Genetic aspects of tropical calcific pancreatitis |
| Q28247574 | Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein |
| Q50032638 | Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice |
| Q21203019 | Hereditary chronic pancreatitis |
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| Q24295201 | Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors |
| Q48445934 | Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice |
| Q43826802 | Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation. |
| Q36200333 | Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction |
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| Q41819239 | Human pancreatitis and the role of cathepsin B. |
| Q60445893 | Hyperbaric oxygen-induced changes in bacterial translocation and acinar ultrastructure in rat acute necrotizing pancreatitis |
| Q33612349 | IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion |
| Q39781982 | Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells |
| Q37403124 | Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis |
| Q37982804 | Impaired autophagy and organellar dysfunction in pancreatitis |
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| Q40123189 | Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-beta1-signaling and upregulation of cathepsin B. |
| Q47739102 | Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression |
| Q39478569 | Inhibition of trypsin-like cysteine proteinases (gingipains) from Porphyromonas gingivalis by tetracycline and its analogues |
| Q44706159 | Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2). |
| Q41628354 | Intra-acinar trypsinogen activation mediates early stages of pancreatic injury but not inflammation in mice with acute pancreatitis |
| Q35005784 | Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis |
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| Q34936085 | Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis |
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| Q41546015 | Legumain is activated in macrophages during pancreatitis |
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