scholarly article | Q13442814 |
P50 | author | Tanja Schirmeister | Q41507108 |
Heidrun Moll | Q21260927 | ||
Thomas Reinheckel | Q56849298 | ||
P2093 | author name string | Manfred B Lutz | |
Angela Schwarz | |||
Bianca Röger | |||
Iris J Gonzalez-Leal | |||
P2860 | cites work | How quantitative differences in dendritic cell maturation can direct TH1/TH2-cell polarization | Q42044718 |
The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors | Q42472217 | ||
Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages | Q43946923 | ||
CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells | Q44219923 | ||
Disparity in IL-12 release in dendritic cells and macrophages in response to Mycobacterium tuberculosis is due to use of distinct TLRs | Q44576601 | ||
Cathepsin L is crucial for a Th1-type immune response during Leishmania major infection. | Q44862470 | ||
Tumor necrosis factor-alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes | Q44879905 | ||
CD8 alpha- and Langerin-negative dendritic cells, but not Langerhans cells, act as principal antigen-presenting cells in leishmaniasis. | Q44910134 | ||
Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania | Q44920559 | ||
Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway | Q45025138 | ||
Specific cathepsin B inhibitor is cell-permeable and activates presentation of TTC in primary human dendritic cells. | Q46018555 | ||
Dendritic cells (DC) activated by CpG DNA ex vivo are potent inducers of host resistance to an intracellular pathogen that is independent of IL-12 derived from the immunizing DC. | Q47644110 | ||
Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells | Q49155579 | ||
Lysosomal cathepsin B plays an important role in antigen processing, while cathepsin D is involved in degradation of the invariant chain inovalbumin-immunized mice. | Q50335825 | ||
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading | Q24328923 | ||
Protease signalling: the cutting edge | Q26852301 | ||
Analyzing real-time PCR data by the comparative C(T) method | Q28131831 | ||
ImageJ for microscopy | Q28253317 | ||
Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and perturbation of hair follicle cycling | Q28590536 | ||
Cathepsin S required for normal MHC class II peptide loading and germinal center development | Q28611850 | ||
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor | Q28646310 | ||
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. | Q29347297 | ||
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow | Q29615498 | ||
Dendritic cells: specialized and regulated antigen processing machines | Q29617085 | ||
Suppression of LPS-induced inflammatory responses in macrophages infected with Leishmania | Q33669426 | ||
Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63. | Q33728493 | ||
Aziridine-2,3-dicarboxylate-based cysteine cathepsin inhibitors induce cell death in Leishmania major associated with accumulation of debris in autophagy-related lysosome-like vacuoles. | Q34309555 | ||
Leishmania mexicana induces limited recruitment and activation of monocytes and monocyte-derived dendritic cells early during infection | Q34456673 | ||
A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts | Q34669706 | ||
Recombinant interleukin 12 cures mice infected with Leishmania major | Q36361742 | ||
The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model | Q36365507 | ||
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice | Q36366305 | ||
Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands | Q36370268 | ||
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity | Q36404267 | ||
Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation | Q36475793 | ||
Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity | Q36751431 | ||
Cathepsin S activity regulates antigen presentation and immunity | Q37382422 | ||
Proteinases as virulence factors in Leishmania spp. infection in mammals. | Q38032623 | ||
Nuclear cysteine cathepsin variants in thyroid carcinoma cells | Q39695008 | ||
Leishmania major parasites induced macrophage tolerance: implication of MAPK and NF-kappaB pathways | Q39812406 | ||
Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-kappaB signaling in macrophages | Q39992739 | ||
Cathepsins are required for Toll-like receptor 9 responses | Q40029240 | ||
Analysis of infection characteristics and antiparasite immune responses in resistant compared with susceptible hosts | Q40102605 | ||
Aziridine-2,3-dicarboxylates, peptidomimetic cysteine protease inhibitors with antileishmanial activity | Q40262609 | ||
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis | Q40735691 | ||
Treatment with cathepsin L inhibitor potentiates Th2-type immune response in Leishmania major-infected BALB/c mice | Q40790202 | ||
The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide | Q40814428 | ||
Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subver | Q40913997 | ||
Regulation of macrophage IL-12 synthesis by Leishmania phosphoglycans | Q40975281 | ||
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. | Q52520769 | ||
Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. | Q53615275 | ||
Switch of CD4+ T cell differentiation from Th2 to Th1 by treatment with cathepsin B inhibitor in experimental leishmaniasis. | Q54126242 | ||
Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells | Q58323356 | ||
Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses | Q58662838 | ||
Silent infection of bone marrow-derived dendritic cells byLeishmania mexicana amastigotes | Q63198732 | ||
Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation | Q63369608 | ||
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology | Q73603855 | ||
Cathepsin B-inhibitor promotes the development of Th1 type protective T cells in mice infected with Leishmania major | Q73935322 | ||
Analysis of cytokine production by inflammatory mouse macrophages at the single-cell level: selective impairment of IL-12 induction in Leishmania-infected cells | Q74494567 | ||
Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells | Q78516497 | ||
Lymph node resident rather than skin-derived dendritic cells initiate specific T cell responses after Leishmania major infection | Q79834668 | ||
Human primary dendritic cell subsets differ in their IL-12 release in response to Leishmania major infection | Q84736379 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | infectious disease | Q18123741 |
Leishmania major | Q1950715 | ||
P304 | page(s) | e3194 | |
P577 | publication date | 2014-09-25 | |
P1433 | published in | PLoS Neglected Tropical Diseases | Q3359737 |
P1476 | title | Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection | |
P478 | volume | 8 |
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