scholarly article | Q13442814 |
P356 | DOI | 10.1002/HUMU.10285 |
P698 | PubMed publication ID | 14695529 |
P50 | author | Miklós Sahin-Tóth | Q38318675 |
P2093 | author name string | Niels Teich | |
Miklós Tóth | |||
Volker Keim | |||
Jian-Min Chen | |||
Helmut Witzigmann | |||
Joachim Mössner | |||
Claude Férec | |||
Cédric Le Maréchal | |||
Karel Caca | |||
Zoltán Kukor | |||
P2860 | cites work | Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation | Q74127323 |
Identification of a novel pancreatitis-associated missense mutation, R116C, in the human cationic trypsinogen gene (PRSS1) | Q77171994 | ||
Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene | Q77385500 | ||
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreat | Q77894569 | ||
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases | Q24300351 | ||
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene | Q24311652 | ||
Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic chronic pancreatitis | Q24681604 | ||
Discrimination of three mutational events that result in a disruption of the R122 primary autolysis site of the human cationic trypsinogen (PRSS1) by denaturing high performance liquid chromatography | Q24795679 | ||
Cathepsin B cleavage of the trypsinogen activation peptide | Q24797108 | ||
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis | Q28138105 | ||
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis | Q28138406 | ||
Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis | Q28145585 | ||
Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis | Q28205812 | ||
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis | Q28250483 | ||
Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis | Q28344965 | ||
A new polymorphism for the RI22H mutation in hereditary pancreatitis | Q28345956 | ||
Mutations of the cationic trypsinogen in hereditary pancreatitis | Q34472573 | ||
Trypsinogen variants in pancreatic juice of healthy volunteers, chronic alcoholics, and patients with pancreatitis and cancer of the pancreas | Q34476170 | ||
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis | Q40735691 | ||
Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis | Q41734787 | ||
Analysis of progress curves by simulations generated by numerical integration | Q42835646 | ||
A CGC>CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis | Q42976586 | ||
Comparative in vitro studies on native and recombinant human cationic trypsins. Cathepsin B is a possible pathological activator of trypsinogen in pancreatitis. | Q43581652 | ||
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen | Q43806616 | ||
Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation. | Q43826802 | ||
R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis | Q43884492 | ||
Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis | Q43946815 | ||
"Loss of function" mutations in the cationic trypsinogen gene (PRSS1) may act as a protective factor against pancreatitis | Q44452899 | ||
Two human trypsinogens. Purification, molecular properties, and N-terminal sequences | Q44455238 | ||
Evolution of trypsinogen activation peptides | Q44495545 | ||
Affinity purification of recombinant trypsinogen using immobilized ecotin. | Q46011088 | ||
Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen | Q46911281 | ||
Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM--a flexible, portable system. | Q52706984 | ||
Human pancreatic secretory trypsin inhibitor | Q68237081 | ||
Effects of chronic alcohol abuse on exocrine pancreatic secretion in man | Q70044313 | ||
An exceptional genealogy for hereditary chronic pancreatitis | Q71214968 | ||
Exclusion of anionic trypsinogen and mesotrypsinogen involvement in hereditary pancreatitis without cationic trypsinogen gene mutations | Q73025220 | ||
Early events in acute pancreatitis | Q73075153 | ||
P433 | issue | 1 | |
P304 | page(s) | 22-31 | |
P577 | publication date | 2004-01-01 | |
P1433 | published in | Human Mutation | Q5937269 |
P1476 | title | Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2) | |
P478 | volume | 23 |
Q35011363 | A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene |
Q30000783 | A conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patients |
Q24675973 | Biochemical models of hereditary pancreatitis |
Q45309271 | Chronic parotitis: not another SPINKosis |
Q54593532 | Detection of a large genomic deletion in the pancreatic secretory trypsin inhibitor (SPINK1) gene. |
Q51796788 | Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene. |
Q37363563 | Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl |
Q37208470 | Genetic aspects of tropical calcific pancreatitis |
Q35162016 | Genetic risk for alcoholic chronic pancreatitis |
Q36235401 | Genetics of pancreatitis. |
Q37869759 | Genetics of pancreatitis: a guide for clinicians |
Q37629167 | Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis |
Q34936085 | Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis |
Q24658116 | Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis |
Q35534772 | Protein surface charge of trypsinogen changes its activation pattern |
Q37255493 | The guinea pig pancreas secretes a single trypsinogen isoform, which is defective in autoactivation. |
Q24620760 | Uncertainties in the classification of human cationic trypsinogen (PRSS1) variants as hereditary pancreatitis-associated mutations |
Q81285595 | [Clinical implications of genetic risk factors of chronic pancreatitis] |
Q81160733 | [Genetic testing for acute or chronic pancreatitis] |
Search more.