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P50 | author | James David Chappell | Q91489970 |
P2093 | author name string | Joshua D Doyle | |
Terence S Dermody | |||
Nobuhiko Katunuma | |||
M Kay Washington | |||
Elizabeth M Johnson | |||
J Denise Wetzel | |||
R Paul McClung | |||
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Structure-based design of specific cathepsin inhibitors and their application to protection of bone metastases of cancer cells | Q43857553 | ||
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A mature and fusogenic form of the Nipah virus fusion protein requires proteolytic processing by cathepsin L. | Q45420084 | ||
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Reovirus: evidence for a second step in the intracellular uncoating and transcriptase activation process | Q70779231 | ||
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Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases | Q71185919 | ||
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice | Q74595052 | ||
The M2 gene segment is involved in the capacity of reovirus type 3Abney to induce the oily fur syndrome in neonatal mice, a S1 gene segment-associated phenotype | Q78724876 | ||
Cathepsin L is essential for onset of autoimmune diabetes in NOD mice | Q34014524 | ||
Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3. | Q34301756 | ||
Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L. | Q34343810 | ||
The role of cathepsins in osteoporosis and arthritis: rationale for the design of new therapeutics | Q34416331 | ||
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c | Q34457741 | ||
Cathepsin L activity controls adipogenesis and glucose tolerance | Q34654358 | ||
Thiol-dependent cathepsins: pathophysiological implications and recent advances in inhibitor design | Q34754118 | ||
Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease | Q35095524 | ||
Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassembly | Q35877228 | ||
Mutations in reovirus outer-capsid protein sigma3 selected during persistent infections of L cells confer resistance to protease inhibitor E64 | Q35887561 | ||
Basic statistical considerations in virological experiments | Q35990979 | ||
The biliary tract in acute murine reovirus 3 infection. Light and electron microscopic study | Q36051629 | ||
The lysosomal cysteine proteases in MHC class II antigen presentation | Q36266499 | ||
Endosomal proteases in antigen presentation | Q36336164 | ||
Molecular basis of reovirus virulence. Role of the M2 gene | Q36344079 | ||
Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands | Q36370268 | ||
Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice | Q36399901 | ||
Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation | Q36475793 | ||
Cysteine cathepsins: multifunctional enzymes in cancer | Q36600996 | ||
Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice. | Q36636134 | ||
Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses. | Q36686120 | ||
Emerging roles of cysteine cathepsins in disease and their potential as drug targets. | Q36740577 | ||
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particles | Q36826294 | ||
Cathepsin cysteine proteases in cardiovascular disease. | Q36830621 | ||
Intracellular digestion of reovirus particles requires a low pH and is an essential step in the viral infectious cycle. | Q36915422 | ||
Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression | Q37015016 | ||
New insights into the roles of endolysosomal cathepsins in the pathogenesis of Alzheimer's disease: cathepsin inhibitors as potential therapeutics | Q37232893 | ||
Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers | Q37500830 | ||
Strategy for nonenveloped virus entry: a hydrophobic conformer of the reovirus membrane penetration protein micro 1 mediates membrane disruption | Q39684830 | ||
Role of endocytosis and cathepsin-mediated activation in Nipah virus entry | Q40002207 | ||
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells | Q40341738 | ||
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry. | Q40344603 | ||
Endocytosis by random initiation and stabilization of clathrin-coated pits | Q40520631 | ||
Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus. | Q40530759 | ||
Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis | Q40561414 | ||
Cathepsin S supports acid-independent infection by some reoviruses | Q40608252 | ||
Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells | Q40734800 | ||
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis | Q40735691 | ||
A role for cathepsin L and cathepsin S in peptide generation for MHC class II presentation | Q40746014 | ||
3-hydroxy-3-methylglutaryl coenzyme A reductase is sterol-dependently cleaved by cathepsin L-type cysteine protease in the isolated endoplasmic reticulum | Q40804350 | ||
Utilization of sialic acid as a coreceptor enhances reovirus attachment by multistep adhesion strengthening | Q40845786 | ||
P433 | issue | 19 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | pathogenesis | Q372016 |
Reovirus | Q69812835 | ||
P304 | page(s) | 9630-9640 | |
P577 | publication date | 2009-07-29 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis | |
P478 | volume | 83 |
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Q28299264 | Apoptosis induction influences reovirus replication and virulence in newborn mice |
Q39406121 | Cell entry-associated conformational changes in reovirus particles are controlled by host protease activity |
Q64991702 | Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process. |
Q53204721 | Expression profile of genes involved in pathogenesis of pediatric Crohn's disease. |
Q37123318 | Genetic determinants of reovirus pathogenesis in a murine model of respiratory infection |
Q42351663 | In search of cathepsins: how reovirus enters host cells |
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Q26775033 | Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus Variants |
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