Clk post-transcriptional control denoises circadian transcription both temporally and spatially

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Clk post-transcriptional control denoises circadian transcription both temporally and spatially is …
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P819ADS bibcode2015NatCo...6.7056L
P6179Dimensions Publication ID1045983051
P356DOI10.1038/NCOMMS8056
P3181OpenCitations bibliographic resource ID1613432
P932PMC publication ID4915573
P698PubMed publication ID25952406

P50authorMichael RosbashQ1297741
Nir FriedmanQ7039821
Shaked AfikQ56908566
P2093author name stringSebastian Kadener
Osnat Bartok
Uri Weissbein
Jerome S Menet
Immanuel Lerner
Chen Gafni
Daniel Haimovich
Victoria Wolfson
P2860cites workMammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylationQ24310618
PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcriptionQ24548191
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The CK2 kinase stabilizes CLOCK and represses its activity in the Drosophila circadian oscillatorQ27316942
Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosisQ27324222
A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timelessQ28273955
Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levelsQ28297806
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Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expressionQ30579303
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Genetic analysis of ectopic circadian clock induction in DrosophilaQ41903154
Mathematical model of the Drosophila circadian clock: loop regulation and transcriptional integrationQ42602895
A role for Drosophila ATX2 in activation of PER translation and circadian behaviorQ42717758
Cold-inducible RNA-binding protein modulates circadian gene expression posttranscriptionallyQ42831327
Drosophila clock can generate ectopic circadian clocksQ47070173
A new role for cryptochrome in a Drosophila circadian oscillator.Q47070472
Resetting the circadian clock by social experience in Drosophila melanogaster.Q52111480
Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.Q52595230
dCLOCK is present in limiting amounts and likely mediates daily interactions between the dCLOCK-CYC transcription factor and the PER-TIM complexQ73469642
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Circadian transcription contributes to core period determination in DrosophilaQ33336761
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The circadian output gene takeout is regulated by Pdp1epsilonQ33664186
Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulatorsQ33781149
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Wild-type circadian rhythmicity is dependent on closely spaced E boxes in the Drosophila timeless promoterQ34011610
Tuning the mammalian circadian clock: robust synergy of two loops.Q34109733
Mammalian genes are transcribed with widely different bursting kineticsQ34171559
VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillatorQ34172689
vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clockQ34176690
MicroRNAs can generate thresholds in target gene expressionQ34209703
Regulation of circadian behavioral output via a MicroRNA-JAK/STAT circuitQ34251948
Noise-mean relationship in mutated promotersQ34347357
Independent photoreceptive circadian clocks throughout DrosophilaQ34446958
CYCLE is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timelessQ34472115
Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker componentQ34639250
A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clockQ34639260
CLOCK-mediated acetylation of BMAL1 controls circadian functionQ34724581
Cellular decision making and biological noise: from microbes to mammalsQ34746711
Intracellular and intercellular processes determine robustness of the circadian clock.Q35051662
Genetics and molecular biology of rhythms in Drosophila and other insectsQ35068742
MicroRNA-9a ensures the precise specification of sensory organ precursors in DrosophilaQ35105982
A recessive mutant of Drosophila Clock reveals a role in circadian rhythm amplitudeQ35160497
Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in DrosophilaQ35968254
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CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in DrosophilaQ36421773
Canalization of development by microRNAsQ36493258
Nascent-Seq analysis of Drosophila cycling gene expressionQ36567931
Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from DrosophilaQ36608877
Denoising feedback loops by thresholding--a new role for microRNAsQ36624317
Genetic redundancy strengthens the circadian clock leading to a narrow entrainment rangeQ36904260
Reevaluation of Drosophila melanogaster's neuronal circadian pacemakers reveals new neuronal classesQ37000983
MiRNAs confer phenotypic robustness to gene networks by suppressing biological noise.Q37331613
The Drosophila melanogaster circadian pacemaker circuitQ37369728
P407language of work or nameEnglishQ1860
P921main subjectcircadian rhythmQ208353
P304page(s)7056
P577publication date2015-05-08
P1433published inNature CommunicationsQ573880
P1476titleClk post-transcriptional control denoises circadian transcription both temporally and spatially
P478volume6