scholarly article | Q13442814 |
P819 | ADS bibcode | 2016PLoSO..1147974M |
P356 | DOI | 10.1371/JOURNAL.PONE.0147974 |
P932 | PMC publication ID | 4726538 |
P698 | PubMed publication ID | 26808141 |
P5875 | ResearchGate publication ID | 291946715 |
P50 | author | Jamie R. K. Marland | Q64499119 |
Michael A Cousin | Q59693288 | ||
Karen Janet Smillie | Q42726692 | ||
P2093 | author name string | Jamie R K Marland | |
P2860 | cites work | Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation | Q24339194 |
The molecular physiology of activity-dependent bulk endocytosis of synaptic vesicles | Q24616029 | ||
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1 | Q24654657 | ||
Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia | Q24678573 | ||
A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome | Q26798983 | ||
Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities | Q26863005 | ||
Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2 | Q27659883 | ||
Fiji: an open-source platform for biological-image analysis | Q27860912 | ||
A conserved family of calcineurin regulators. | Q27933946 | ||
Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes | Q28118988 | ||
DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways | Q28138804 | ||
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling | Q28139025 | ||
Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease | Q28210455 | ||
App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome | Q28511479 | ||
Essential role of phosphoinositide metabolism in synaptic vesicle recycling | Q28511682 | ||
Adaptor protein complexes 1 and 3 are essential for generation of synaptic vesicles from activity-dependent bulk endosomes | Q28581279 | ||
Intersectin is a negative regulator of dynamin recruitment to the synaptic endocytic zone in the central synapse. | Q30159491 | ||
Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure | Q32054544 | ||
Calcineurin is universally involved in vesicle endocytosis at neuronal and nonneuronal secretory cells | Q33804443 | ||
Amyloid precursor protein is trafficked and secreted via synaptic vesicles | Q33893776 | ||
Activity-dependent bulk endocytosis and clathrin-dependent endocytosis replenish specific synaptic vesicle pools in central nerve terminals | Q33929652 | ||
Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. | Q34035851 | ||
The role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses | Q34196522 | ||
RCAN1 regulates vesicle recycling and quantal release kinetics via effects on calcineurin activity | Q85385985 | ||
Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome. | Q46035669 | ||
DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease | Q46819146 | ||
The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling | Q46876545 | ||
Down syndrome: the brain in trisomic mode | Q48287894 | ||
Dendritic atrophy in children with Down's syndrome | Q48296709 | ||
The kinetics of synaptic vesicle reacidification at hippocampal nerve terminals. | Q48640074 | ||
Synaptic development in the human fetus: a morphometric analysis of normal and Down's syndrome neocortex | Q48692759 | ||
Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. | Q51979066 | ||
Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. | Q51995807 | ||
Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome. | Q52005136 | ||
A mouse model for Down syndrome exhibits learning and behaviour deficits. | Q52013436 | ||
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). | Q52166624 | ||
Amino acid neurotransmitter deficits in adult Down's syndrome brain tissue | Q61714007 | ||
Phosphorylation by Dyrk1A of clathrin coated vesicle-associated proteins: identification of the substrate proteins and the effects of phosphorylation | Q34238748 | ||
Over-expression of RCAN1 causes Down syndrome-like hippocampal deficits that alter learning and memory. | Q34268889 | ||
Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase | Q34280119 | ||
Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex | Q34355386 | ||
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. | Q34504363 | ||
The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesicles | Q34987475 | ||
Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1. | Q35069723 | ||
Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome | Q35573506 | ||
Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations | Q35745983 | ||
Increased cortical synaptic activation of TrkB and downstream signaling markers in a mouse model of Down Syndrome | Q36399166 | ||
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn. | Q36422268 | ||
Synaptic vesicle generation from activity-dependent bulk endosomes requires calcium and calcineurin. | Q36660705 | ||
Fast neurotransmitter release regulated by the endocytic scaffold intersectin | Q36855303 | ||
Short-term treatment with the GABAA receptor antagonist pentylenetetrazole produces a sustained pro-cognitive benefit in a mouse model of Down's syndrome | Q36965872 | ||
Control of synaptic vesicle endocytosis by an extracellular signalling molecule | Q37187025 | ||
Synaptic degeneration in Alzheimer's disease | Q37458270 | ||
Ultrafast endocytosis at mouse hippocampal synapses. | Q37642826 | ||
Presynaptic dysfunction in Huntington's disease. | Q37713855 | ||
Presynaptic function in health and disease | Q37877363 | ||
Synaptic vesicle endocytosis | Q38024048 | ||
Synaptic Vesicle Endocytosis and Endosomal Recycling in Central Nerve Terminals: Discrete Trafficking Routes? | Q38229899 | ||
Synaptic vesicle generation from central nerve terminal endosomes | Q38262876 | ||
Activity-dependent phosphorylation of dynamin 1 at serine 857. | Q39303566 | ||
Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. | Q39751968 | ||
Deficits in hippocampal CA1 LTP induced by TBS but not HFS in the Ts65Dn mouse: a model of Down syndrome. | Q40418155 | ||
Activity-dependent control of slow synaptic vesicle endocytosis by cyclin-dependent kinase 5. | Q40803584 | ||
Bulk synaptic vesicle endocytosis is rapidly triggered during strong stimulation | Q41599069 | ||
Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome | Q41811378 | ||
CDK5 serves as a major control point in neurotransmitter release. | Q41862687 | ||
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. | Q42467654 | ||
Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome | Q42483994 | ||
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. | Q42497675 | ||
Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions | Q42694136 | ||
Overexpression of Dyrk1A causes the defects in synaptic vesicle endocytosis | Q42785129 | ||
Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome | Q42801227 | ||
MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins | Q43055134 | ||
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory | Q43815520 | ||
Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome. | Q46020053 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Down syndrome | Q47715 |
P304 | page(s) | e0147974 | |
P577 | publication date | 2016-01-25 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome | |
P478 | volume | 11 |
Q90400921 | RCAN1 Knockdown Reverts Defects in the Number of Calcium-Induced Exocytotic Events in a Cellular Model of Down Syndrome | cites work | P2860 |
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