| scholarly article | Q13442814 |
| P50 | author | Alexander M Kleschevnikov | Q57448183 |
| P2093 | author name string | Robert C Malenka | |
| Pavel V Belichenko | |||
| William C Mobley | |||
| Charles J Epstein | |||
| Angela J Villar | |||
| P2860 | cites work | Coupling actin dynamics and membrane dynamics during endocytosis | Q27932391 |
| GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors | Q28568974 | ||
| APP processing and synaptic function | Q29615873 | ||
| A mouse model for Down syndrome exhibits learning and behaviour deficits. | Q52013436 | ||
| Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice. | Q52028645 | ||
| Age-related deficits in context discrimination learning in Ts65Dn mice that model Down syndrome and Alzheimer's disease. | Q52125750 | ||
| Differential gene expression studies to explore the molecular pathophysiology of Down syndrome | Q57161912 | ||
| Implicit and explicit memory: a functional dissociation in persons with Down syndrome | Q73457679 | ||
| Afferent high strength tetanizations favour potentiation of the NMDA vs. AMPA receptor-mediated component of field EPSP in CA1 hippocampal slices of rats | Q73822301 | ||
| On the cause of mental retardation in Down syndrome: extrapolation from full and segmental trisomy 16 mouse models | Q73835480 | ||
| GluR5 kainate receptor activation in interneurons increases tonic inhibition of pyramidal cells | Q77299374 | ||
| Interneurons of the hippocampus | Q29618946 | ||
| Long-term potentiation--a decade of progress? | Q29619421 | ||
| Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion | Q33943282 | ||
| Behavioral phenotype of individuals with Down syndrome | Q33971581 | ||
| Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin1 on amyloid biochemistry and pathology in APP/London mice | Q34071519 | ||
| Too much of a good thing: mechanisms of gene action in Down syndrome. | Q34137795 | ||
| Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome | Q34176485 | ||
| Accessory factors in clathrin-dependent synaptic vesicle endocytosis | Q34189417 | ||
| Down's syndrome | Q34191091 | ||
| Murine models for Down syndrome | Q34375884 | ||
| Mitogenesis and endocytosis: What's at the INTERSECTIoN? | Q34405524 | ||
| Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory | Q35126365 | ||
| Down syndrome phenotypes: the consequences of chromosomal imbalance | Q35344729 | ||
| Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome | Q36693574 | ||
| 2001 William Allan Award Address. From Down syndrome to the "human" in "human genetics" | Q37360568 | ||
| The neuropsychology of Down syndrome: evidence for hippocampal dysfunction | Q38520897 | ||
| Short-term synaptic plasticity | Q38613257 | ||
| Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat | Q40232008 | ||
| Epilepsy in Down syndrome: clinical aspects and possible mechanisms. | Q40711833 | ||
| Segmental trisomy as a mouse model for Down syndrome | Q40718246 | ||
| Excitation and inhibition in epilepsy | Q41156248 | ||
| Synaptic activation of kainate receptors on hippocampal interneurons | Q41644763 | ||
| Beta-amyloid peptides as direct cholinergic neuromodulators: a missing link? | Q41701369 | ||
| Behavioral comparison of 4 and 6 month-old Ts65Dn mice: age-related impairments in working and reference memory | Q42435702 | ||
| Drugs of abuse and stress trigger a common synaptic adaptation in dopamine neurons | Q44322848 | ||
| Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome | Q46866532 | ||
| Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions | Q47415659 | ||
| Vasoactive intestinal peptide in the brain of a mouse model for Down syndrome | Q47644276 | ||
| MRI volumes of the hippocampus and amygdala in adults with Down's syndrome with and without dementia | Q48238093 | ||
| Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice | Q48242315 | ||
| Methods for whole-cell recording from visually preselected neurons of perirhinal cortex in brain slices from young and aging rats | Q48300861 | ||
| Strong paired pulse depression of dentate granule cells in slices from patients with temporal lobe epilepsy | Q48344400 | ||
| Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurones | Q48425356 | ||
| Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice | Q48498793 | ||
| Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome | Q48516987 | ||
| Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments | Q48603397 | ||
| Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome | Q48718482 | ||
| The hippocampus in Down's syndrome. | Q48753095 | ||
| Spatial memory deficits in segmental trisomic Ts65Dn mice. | Q48776317 | ||
| Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study. | Q48923372 | ||
| Ts65Dn mice, a model for Down syndrome, have deficits in context discrimination learning suggesting impaired hippocampal function. | Q49061146 | ||
| Effects of diazepam on hippocampal excitability in the rat: action in the dentate area. | Q51868087 | ||
| Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease. | Q51960971 | ||
| Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. | Q51979066 | ||
| Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. | Q51995807 | ||
| Long-term memory in mental retardation: evidence for a specific impairment in subjects with Down's syndrome. | Q52005572 | ||
| P433 | issue | 37 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | long-term potentiation | Q1805481 |
| P304 | page(s) | 8153-8160 | |
| P577 | publication date | 2004-09-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome | |
| P478 | volume | 24 |
| Q35509854 | A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome |
| Q33790196 | A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction |
| Q30495192 | A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions |
| Q36274714 | A network of autism linked genes stabilizes two pools of synaptic GABA(A) receptors |
| Q37423613 | A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome |
| Q96769250 | A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21 |
| Q47690390 | A third copy of the Down syndrome cell adhesion molecule (Dscam) causes synaptic and locomotor dysfunction in Drosophila |
| Q36393590 | Aberrant dendritic excitability: a common pathophysiology in CNS disorders affecting memory? |
| Q37185647 | Abnormal brain synchrony in Down Syndrome. |
| Q41978368 | Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome |
| Q36665885 | Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. |
| Q50891308 | Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test. |
| Q48370031 | Adaptation of the Arizona Cognitive Task Battery for use with the Ts65Dn mouse model (Mus musculus) of Down syndrome |
| Q33764911 | Adaptive and pathological inhibition of neuroplasticity associated with circadian rhythms and sleep |
| Q37370345 | Adult reversal of cognitive phenotypes in neurodevelopmental disorders |
| Q36119092 | Adult-onset fluoxetine treatment does not improve behavioral impairments and may have adverse effects on the Ts65Dn mouse model of Down syndrome |
| Q37108156 | Advances on the understanding of the origins of synaptic pathology in AD. |
| Q47155189 | Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome |
| Q36465744 | Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome |
| Q50534102 | Alterations of in vivo CA1 network activity in Dp(16)1Yey Down syndrome model mice. |
| Q38921687 | Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy. |
| Q48455685 | Altered distribution of hippocampal interneurons in the murine Down Syndrome model Ts65Dn |
| Q38565706 | Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome |
| Q48452284 | Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome |
| Q35744424 | Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican |
| Q33990273 | An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes |
| Q33503645 | Anesthetics rapidly promote synaptogenesis during a critical period of brain development. |
| Q37543845 | Aneuploidy: from a physiological mechanism of variance to Down syndrome |
| Q36126681 | Antioxidants in Down syndrome |
| Q36293795 | Assessment of Cognitive Scales to Examine Memory, Executive Function and Language in Individuals with Down Syndrome: Implications of a 6-month Observational Study |
| Q36989218 | Beta-amyloid modulation of synaptic transmission and plasticity |
| Q30477204 | Brain cholesterol turnover required for geranylgeraniol production and learning in mice |
| Q30474810 | Brain plasticity and disease: a matter of inhibition |
| Q26781609 | Building an adaptive brain across development: targets for neurorehabilitation must begin in infancy |
| Q47823260 | CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation (MCS). |
| Q42449033 | Cadherin-13, a risk gene for ADHD and comorbid disorders, impacts GABAergic function in hippocampus and cognition |
| Q39725949 | Calcium channel blockade attenuates abnormal synaptic transmission in the dentate gyrus elicited by entorhinal amyloidopathy |
| Q81235261 | Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects |
| Q28478194 | Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB |
| Q48617670 | Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases |
| Q46486717 | Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons |
| Q35418044 | Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model |
| Q31126337 | Co-expression network analysis of Down's syndrome based on microarray data |
| Q41811378 | Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome |
| Q43109275 | Cognitive enhancement therapy for a model of Down syndrome |
| Q30459302 | Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer |
| Q48296559 | Computational modeling of GABAA receptor-mediated paired-pulse inhibition in the dentate gyrus. |
| Q26745413 | DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome |
| Q34359769 | DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors |
| Q47666263 | Decreasing the Expression of GABAA α5 Subunit-Containing Receptors Partially Improves Cognitive, Electrophysiological, and Morphological Hippocampal Defects in the Ts65Dn Model of Down Syndrome. |
| Q51897983 | Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. |
| Q36138353 | Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. |
| Q34036957 | Deficits in human trisomy 21 iPSCs and neurons |
| Q38865366 | Dementia in Down's syndrome |
| Q26995242 | Dendritic spine dysgenesis in autism related disorders |
| Q33966522 | Developmentally altered inhibition in Ts65Dn, a mouse model of Down syndrome |
| Q44195349 | Differential balance of prefrontal synaptic activity in successful versus unsuccessful cognitive aging |
| Q89495628 | Differential expression profile study and gene function analysis of maternal foetal-derived circRNA for screening for Down's syndrome |
| Q41968187 | Does the learning deficit observed under an incremental repeated acquisition schedule of reinforcement in Ts65Dn mice, a model for Down syndrome, change as they age? |
| Q27300997 | Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues |
| Q36698095 | Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination |
| Q36004582 | Down syndrome and genetics - a case of linked histories. |
| Q39060506 | Down syndrome and the complexity of genome dosage imbalance |
| Q36681400 | Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21. |
| Q22241596 | Down syndrome: searching for the genetic culprits |
| Q48287894 | Down syndrome: the brain in trisomic mode |
| Q55042028 | Down's syndrome: critical genes in a critical region. |
| Q34010790 | Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome |
| Q37734742 | Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer's-like memory deficits in the Ts65Dn mouse model of Down syndrome |
| Q42997861 | Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome |
| Q30497997 | Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice. |
| Q24619170 | Emerging Pharmacotherapies for Neurodevelopmental Disorders |
| Q89997369 | Enhanced Dendritic Inhibition and Impaired NMDAR Activation in a Mouse Model of Down Syndrome |
| Q35632680 | Environmental enrichment decreases GABAergic inhibition and improves cognitive abilities, synaptic plasticity, and visual functions in a mouse model of Down syndrome |
| Q35661604 | Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn mouse model of Down syndrome |
| Q46652242 | Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome |
| Q35569636 | Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine |
| Q34989741 | Excitation/inhibition imbalance and impaired synaptic inhibition in hippocampal area CA3 of Mecp2 knockout mice |
| Q46097919 | Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome |
| Q26796321 | Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders |
| Q36111747 | From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome |
| Q38435508 | G Protein-Gated K+ Channel Ablation in Forebrain Pyramidal Neurons Selectively Impairs Fear Learning. |
| Q42493391 | G-protein-associated signal transduction processes are restored after postweaning environmental enrichment in Ts65Dn, a Down syndrome mouse model |
| Q48376883 | GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. |
| Q27300708 | GABA(A) receptor-mediated acceleration of aging-associated memory decline in APP/PS1 mice and its pharmacological treatment by picrotoxin |
| Q30421260 | GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism |
| Q37775217 | GABAB-GIRK2-mediated signaling in Down syndrome. |
| Q38175971 | GABAergic dysfunction in pediatric neuro-developmental disorders |
| Q39324113 | GABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role of App. |
| Q47775741 | GABAergic inhibition gates excitatory LTP in perirhinal cortex. |
| Q42742631 | GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice |
| Q40778694 | GluN2B antagonism affects interneurons and leads to immediate and persistent changes in synaptic plasticity, oscillations, and behavior |
| Q64059897 | Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome |
| Q37698148 | Glutamatergic transmission aberration: a major cause of behavioral deficits in a murine model of Down's syndrome. |
| Q33412381 | Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A. |
| Q33552991 | Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model |
| Q36497216 | Highly specific structural plasticity of inhibitory circuits in the adult neocortex |
| Q27312111 | Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome |
| Q57472015 | Hippocampal deficits in neurodevelopmental disorders |
| Q24656538 | Hippocampal-dependent learning requires a functional circadian system |
| Q37463959 | Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits |
| Q46184199 | Hyperactive interneurons impair learning in a neurofibromatosis model |
| Q36637693 | Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis |
| Q35573506 | Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome |
| Q33655637 | Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy |
| Q43426815 | Impairment of in vivo theta-burst long-term potentiation and network excitability in the dentate gyrus of synaptopodin-deficient mice lacking the spine apparatus and the cisternal organelle. |
| Q33404261 | Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome |
| Q35079696 | Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease |
| Q26768593 | Implications of GABAergic Neurotransmission in Alzheimer's Disease |
| Q38858096 | Improving Memory and Cognition in Individuals with Down Syndrome |
| Q37407381 | In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. |
| Q37622021 | Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression |
| Q36399166 | Increased cortical synaptic activation of TrkB and downstream signaling markers in a mouse model of Down Syndrome |
| Q35675287 | Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome |
| Q34563831 | Increased long-term potentiation at medial-perforant path-dentate granule cell synapses induced by selective inhibition of histone deacetylase 3 requires Fragile X mental retardation protein |
| Q42054322 | Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome |
| Q48602918 | Intensive voluntary wheel running may restore circadian activity rhythms and improves the impaired cognitive performance of arrhythmic Djungarian hamsters. |
| Q36332872 | Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP |
| Q36290045 | Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus. |
| Q34247716 | Interneuron dysfunction in psychiatric disorders |
| Q58609012 | Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome |
| Q37912174 | Is it possible to improve neurodevelopmental abnormalities in Down syndrome? |
| Q30530902 | Lithium rescues synaptic plasticity and memory in Down syndrome mice |
| Q33598454 | Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model |
| Q51959982 | Metaplasticity: tuning synapses and networks for plasticity. |
| Q36981715 | Mitochondrial dysfunction, oxidative stress, regulation of exocytosis and their relevance to neurodegenerative diseases |
| Q37591118 | Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. |
| Q33659830 | Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives |
| Q36111546 | Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeutics |
| Q27021454 | Molecular aspects of age-related cognitive decline: the role of GABA signaling |
| Q33625613 | Molecular basis of pharmacotherapies for cognition in Down syndrome |
| Q28542515 | Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome |
| Q35661597 | Mouse models for Down syndrome-associated developmental cognitive disabilities |
| Q26863005 | Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities |
| Q38494811 | Neural plasticity and memory: molecular mechanism |
| Q36415807 | Neurofibromatosis type 1: new insights into neurocognitive issues |
| Q34872465 | Neurofibromin regulation of ERK signaling modulates GABA release and learning |
| Q38607518 | New Perspectives for the Rescue of Cognitive Disability in Down Syndrome |
| Q37326433 | Normal protein composition of synapses in Ts65Dn mice: a mouse model of Down syndrome |
| Q48410737 | Novel object recognition of Djungarian hamsters depends on circadian time and rhythmic phenotype |
| Q37658290 | Nurturing brain plasticity: impact of environmental enrichment. |
| Q39945571 | Nutritional n-3 PUFA Deficiency Abolishes Endocannabinoid Gating of Hippocampal Long-Term Potentiation. |
| Q92304592 | OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome |
| Q28288207 | Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome |
| Q22241936 | On the promise of pharmacotherapies targeted at cognitive and neurodegenerative components of Down syndrome |
| Q34133976 | Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome |
| Q21129461 | Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models |
| Q91872297 | Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society |
| Q55313635 | Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome. |
| Q30422188 | Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations |
| Q46020053 | Pharmacotherapy for cognitive impairment in a mouse model of Down syndrome. |
| Q28486301 | Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome |
| Q92940036 | Plasticity of Synaptic Transmission in Human Stem Cell-Derived Neural Networks |
| Q37617345 | Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment |
| Q34500663 | Prenatal treatment prevents learning deficit in Down syndrome model |
| Q64118241 | Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models |
| Q36826500 | Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome |
| Q46944762 | Promotion of neuronal plasticity by (-)-epigallocatechin-3-gallate |
| Q22252566 | Prospects for Improving Brain Function in Individuals with Down Syndrome |
| Q90400921 | RCAN1 Knockdown Reverts Defects in the Number of Calcium-Induced Exocytotic Events in a Cellular Model of Down Syndrome |
| Q37705804 | RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. |
| Q24530286 | Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome |
| Q34035851 | Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome. |
| Q48585286 | Regulation of α-synuclein expression in Down syndrome |
| Q43109273 | Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome. |
| Q58553485 | Restoring microglial and astroglial homeostasis using DNA immunization in a Down Syndrome mouse model |
| Q48278664 | Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome. |
| Q37260909 | Reversing neurodevelopmental disorders in adults |
| Q55644124 | Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities. |
| Q46193918 | Rodent models in Down syndrome research: impact and future opportunities. |
| Q37855556 | STDP and Mental Retardation: Dysregulation of Dendritic Excitability in Fragile X Syndrome |
| Q36965872 | Short-term treatment with the GABAA receptor antagonist pentylenetetrazole produces a sustained pro-cognitive benefit in a mouse model of Down's syndrome |
| Q36399208 | Sleep and EEG features in genetic models of Down syndrome |
| Q64990788 | Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities. |
| Q35177041 | Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice |
| Q34872866 | Structural basis for the role of inhibition in facilitating adult brain plasticity |
| Q90486313 | Suprachiasmatic lesions restore object recognition in down syndrome model mice |
| Q27324486 | Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome |
| Q46464782 | Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships |
| Q28077671 | Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students |
| Q47727311 | Target-specific vulnerability of excitatory synapses leads to deficits in associative memory in a model of intellectual disorder. |
| Q37361341 | The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome |
| Q35592144 | The Down syndrome critical region regulates retinogeniculate refinement |
| Q37683060 | The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome |
| Q30438111 | The alpha1 subunit of the GABA(A) receptor modulates fear learning and plasticity in the lateral amygdala |
| Q37868164 | The contribution of GABAergic dysfunction to neurodevelopmental disorders |
| Q46851027 | The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. |
| Q24679420 | The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome |
| Q36916585 | The kinesin superfamily protein KIF17: one protein with many functions |
| Q36973492 | The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases |
| Q36021399 | The power of comparative and developmental studies for mouse models of Down syndrome |
| Q30474023 | The use of mouse models to understand and improve cognitive deficits in Down syndrome |
| Q45181313 | Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of Down syndrome |
| Q26779297 | Timing of therapies for Down syndrome: the sooner, the better |
| Q46349804 | Transcriptional dysregulation causes altered modulation of inhibition by haloperidol |
| Q93119478 | Transcriptome and Proteome Profiling of Neural Induced Pluripotent Stem Cells from Individuals with Down Syndrome Disclose Dynamic Dysregulations of Key Pathways and Cellular Functions |
| Q60919486 | Transient Cognitive Impairment in Epilepsy |
| Q36073232 | Transmission of trisomy decreases with maternal age in mouse models of Down syndrome, mirroring a phenomenon in human Down syndrome mothers |
| Q35740129 | Trisomy 21 and early brain development |
| Q31104439 | Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice. |
| Q35787216 | Trisomy of the G protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and synaptic plasticity in mice |
| Q48375391 | Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current |
| Q33754886 | Unbalance between Excitation and Inhibition in Phenylketonuria, a Genetic Metabolic Disease Associated with Autism |
| Q91062464 | Unbalanced dendritic inhibition of CA1 neurons drives spatial-memory deficits in the Ts2Cje Down syndrome model |
| Q33238943 | Understanding the basis for Down syndrome phenotypes |
| Q37045414 | Weaker control of the electrical properties of cerebellar granule cells by tonically active GABAA receptors in the Ts65Dn mouse model of Down's syndrome. |
| Q26740071 | Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders |
| Q38172119 | Wnts in adult brain: from synaptic plasticity to cognitive deficiencies |
Search more.