Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease

scientific article (publication date: 2011)

Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...621108T
P356DOI10.1371/JOURNAL.PONE.0021108
P3181OpenCitations bibliographic resource ID3383029
P932PMC publication ID3119678
P698PubMed publication ID21712989
P5875ResearchGate publication ID51451856

P50authorGen SobueQ67219868
Hideyuki TakeuchiQ87350460
Koji YamanakaQ37377501
Mariko NodaQ42177315
P2093author name stringYan Zhou
Hua Li
Jun Sato
Hiroyuki Mizoguchi
Rarami Mori
Akio Suzumura
Jun Kawanokuchi
Shijie Jin
Tetsuya Mizuno
Bijay Parajuli
Yoshifumi Sonobe
Yukiko Doi
Endong Li
Jianfeng Liang
Satoko Yasuoka
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Effective reduction of infarct volume by gap junction blockade in a rodent model of strokeQ48577890
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Microglia at brain stab wounds express connexin 43 and in vitro form functional gap junctions after treatment with interferon-gamma and tumor necrosis factor-alphaQ35059879
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Astrocytic gap junction blockage and neuronal Ca2+ oscillation in neuron-astrocyte cocultures in vitroQ42459376
Functional and morphological changes induced by transient in vivo ischemiaQ42492866
Ischemia-induced brain damage depends on specific gap-junctional couplingQ43937493
Alzheimer's amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytesQ44497733
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Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transportQ45216891
Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in miceQ46124391
Blockade of microglial glutamate release protects against ischemic brain injuryQ46385482
Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitorsQ46614579
Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicityQ46645810
Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.Q46733868
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
amyotrophic lateral sclerosisQ206901
P304page(s)e21108
P577publication date2011-01-01
P1433published inPLOS OneQ564954
P1476titleBlockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease
P478volume6

Reverse relations

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