Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain

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Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...995760M
P356DOI10.1371/JOURNAL.PONE.0095760
P932PMC publication ID3994142
P698PubMed publication ID24752617
P5875ResearchGate publication ID261771629

P2093author name stringHitomi Kanno
Kazushige Mizoguchi
Yasushi Ikarashi
Yoshio Kase
P2860cites workThe blood-brain barrier permeability of 18β-glycyrrhetinic acid, a major metabolite of glycyrrhizin in Glycyrrhiza root, a constituent of the traditional Japanese medicine yokukansanQ47211312
Isoliquiritigenin is a novel NMDA receptor antagonist in kampo medicine yokukansanQ47288597
Yokukansan, a traditional Japanese medicine, ameliorates memory disturbance and abnormal social interaction with anti-aggregation effect of cerebral amyloid β proteins in amyloid precursor protein transgenic miceQ47322870
Ameliorative effect of traditional Japanese medicine yokukansan on age-related impairments of working memory and reversal learning in ratsQ47331446
Age-related changes of astorocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sectorQ48247897
Astrocyte-derived ATP modulates depressive-like behaviorsQ48478374
Glutamate transporter protein subtypes are expressed differentially during rat CNS development.Q48617168
Geissoschizine methyl ether, an alkaloid in Uncaria hook, is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansanQ48669381
Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brainQ49142951
Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat.Q52062439
Glycyrrhetinic acid bound to 11 beta-hydroxysteroid dehydrogenase in rat liver microsomesQ67589088
Specific binding of glycyrrhetinic acid to the rat liver membraneQ70220127
Bioavailability study of glycyrrhetic acid after oral administration of glycyrrhizin in rats; relevance to the intestinal bacterial hydrolysisQ71763838
The synthesis of 18beta-glycyrrhetinic acid derivatives which have increased antiproliferative and apoptotic effects in leukemia cellsQ80473192
Amyloid β-induced death in neurons involves glial and neuronal hemichannelsQ83750709
Probenecid, a gout remedy, inhibits pannexin 1 channelsQ24647558
Genome-wide atlas of gene expression in the adult mouse brainQ26253934
Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's diseaseQ27334874
Localization of neuronal and glial glutamate transportersQ28238076
11beta-Hydroxysteroid dehydrogenase in the brain: a novel regulator of glucocorticoid action?Q28301624
Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampusQ28343188
Synchronized oscillations at alpha and theta frequencies in the lateral geniculate nucleusQ33201809
Specific glial functions contribute to schizophrenia susceptibilityQ33762530
Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compoundsQ34011396
GFAP in health and disease.Q34158294
A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients.Q34554967
Yokukansan in the treatment of behavioral and psychological symptoms of dementia: a systematic review and meta-analysis of randomized controlled trialsQ34566324
Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cellsQ34981292
NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's diseaseQ35022998
Emerging complexities in identity and function of glial connexinsQ36088580
The gap junction proteome and its relationship to diseaseQ37640469
Binding of Glycyrrhetinic Acid to Kidney Mineralocorticoid and Glucocorticoid Receptors1Q39936780
Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease.Q42352469
Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practiceQ43149382
Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytesQ43264337
Effects of yokukansan, a traditional Japanese medicine, on memory disturbance and behavioral and psychological symptoms of dementia in thiamine-deficient ratsQ43267459
Inhibition of gap junction hemichannels by chloride channel blockersQ43916372
Reversible inhibition of intercellular junctional communication by glycyrrhetinic acidQ44325495
Differential damage in the frontal cortex with aging, sporadic and familial Alzheimer's diseaseQ44453943
Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in miceQ46124391
Effect of yokukansan on the behavioral and psychological symptoms of dementia in elderly patients with Alzheimer's disease.Q46166311
Blockade of microglial glutamate release protects against ischemic brain injuryQ46385482
Suppressive effect of Yokukansan on excessive release of glutamate and aspartate in the hippocampus of zinc-deficient ratsQ46568961
Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brainQ46752254
Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional couplingQ46899519
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)e95760
P577publication date2014-04-21
P1433published inPLOS OneQ564954
P1476titleSpecific binding and characteristics of 18β-glycyrrhetinic acid in rat brain
P478volume9

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cites work (P2860)
Q38325839Autoradiography techniques and quantification of drug distribution
Q42363344Cellular Pharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan on Brain Cells
Q57458436Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?
Q47838951Effects of Glycyrrhetinic Acid on GSH Synthesis Induced by Realgar in the Mouse Hippocampus: Involvement of System [Formula: see text], System [Formula: see text], MRP-1, and Nrf2.
Q42367703Influences of yokukansankachimpihange on aggressive behavior of zinc-deficient mice and actions of the ingredients on excessive neural exocytosis in the hippocampus of zinc-deficient rats
Q39220519Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects
Q26745471Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients

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