Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

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Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...618525B
P356DOI10.1371/JOURNAL.PONE.0018525
P932PMC publication ID3073968
P698PubMed publication ID21494547
P5875ResearchGate publication ID51052668

P50authorSergio E. ChiarellaQ55476005
Gökhan M MutluQ88316639
Andrew J GhioQ88657431
P2093author name stringG R Scott Budinger
David Green
Hau C Kwaan
Ece A Mutlu
Angel Gonzalez
Daniela Urich
Kathryn A Radigan
Recep Nigdelioglu
Saul Soberanes
Nancy Foiles
Ivy Weiss
Joanne L McKell
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Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysisQ29617291
Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteersQ29618549
Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal modelQ29618580
Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart diseaseQ29618881
Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditionsQ34217461
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Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsivenessQ35232971
Air pollution and inflammation (interleukin-6, C-reactive protein, fibrinogen) in myocardial infarction survivorsQ35879702
Ambient particulate matter accelerates coagulation via an IL-6-dependent pathwayQ35995696
The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factorQ36225788
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Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation.Q37247458
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Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphismsQ37331167
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High plasminogen activator inhibitor and tissue plasminogen activator levels in plasma precede a first acute myocardial infarction in both men and women: evidence for the fibrinolytic system as an independent primary risk factor.Q50755801
Bone marrow plasminogen activator inhibitor-1 influences the development of obesity.Q51491433
The 'PAI-1 paradox' in vascular remodeling.Q52591313
TNF-α, but not IL-6, stimulates plasminogen activator inhibitor-1 expression in human subcutaneous adipose tissueQ56240278
Air Pollution and Markers of Inflammation and Coagulation in Patients with Coronary Heart DiseaseQ57012260
Effects of exposure to air pollution on blood coagulationQ57208390
Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart StudyQ72235431
Septic shock and acute lung injury in rabbits with peritonitis: failure of the neutrophil response to localized infectionQ73513206
Inflammatory lung injury after bronchial instillation of air pollution particlesQ74420368
Fast detection of tissue factor and tissue factor pathway inhibitor messenger RNA in endothelial cells and monocytes by sensitive reverse transcription-polymerase chain reactionQ77747908
The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injuryQ81711993
Ambient air particulate matter exposure and tissue factor expression in atherosclerosisQ94689295
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)e18525
P577publication date2011-01-01
P1433published inPLOS OneQ564954
P1476titleParticulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms
P478volume6

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