Expression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization.

scientific article

Expression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.73.9.7497-7504.1999
P932PMC publication ID104276
P698PubMed publication ID10438839

P2093author name stringInchauspé G
Trépo C
Karayiannis P
Depla E
Maertens G
Fournillier A
Vidalin O
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage colony-stimulating factor gene.Q27469577
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DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsidQ27480298
Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexinQ27480329
Formation of native hepatitis C virus glycoprotein complexes.Q27480776
Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virusQ27480822
Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection modeQ27480864
Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis virusesQ27485996
Expression and identification of hepatitis C virus polyprotein cleavage productsQ27486022
Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia virusesQ27486074
Expression of processed envelope protein of hepatitis C virus in mammalian and insect cellsQ27486219
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An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitisQ27860909
Hepatitis C virus infection is associated with the development of hepatocellular carcinomaQ28131791
Protein folding in the cellQ29547792
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cellsQ29615897
Vaccination of chimpanzees against infection by the hepatitis C virusQ29615899
Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to virusesQ35793550
Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein.Q35854300
Gene inoculation generates immune responses against human immunodeficiency virus type 1Q36284135
Sequence variation in hepatitis C viral isolates.Q36472670
Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities.Q36633402
DNA immunization: induction of higher avidity antibody and effect of route on T cell cytotoxicity.Q36828240
Therapy of Hepatitis CQ40435919
Molecular chaperones in protein folding: the art of avoiding sticky situationsQ40621904
Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteinsQ41027365
Characterization of truncated forms of hepatitis C virus glycoproteins.Q41091382
Complex processing and protein:protein interactions in the E2:NS2 region of HCV.Q41436960
Gene vaccination: plasmid DNA is more than just a blueprintQ41724485
A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell culturesQ42978625
Plasmid DNA expressing a secreted or a nonsecreted form of hepatitis C virus nucleocapsid: comparative studies of antibody and T-helper responses following genetic immunizationQ42981690
Modulation of immune responses to hepatitis C virus envelope E2 protein following injection of plasmid DNA using single or combined delivery routesQ42988946
Characterization of human monoclonal antibodies specific to the hepatitis C virus glycoprotein E2 with in vitro binding neutralization propertiesQ42990001
High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C.Q42990186
Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachmentQ43036993
Processing of the E1 glycoprotein of hepatitis C virus expressed in mammalian cellsQ43046660
Heterologous protection against influenza by injection of DNA encoding a viral proteinQ43828996
Direct gene transfer into mouse muscle in vivoQ44656494
Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA.Q45881597
Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.Q52845358
Influence of cellular location of expressed antigen on the efficacy of DNA vaccination: cytotoxic T lymphocyte and antibody responses are suboptimal when antigen is cytoplasmic after intramuscular DNA immunizationQ74184098
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
Hepatitis C virusQ708693
hepatitis CQ154869
virologyQ7215
immunizationQ1415366
P304page(s)7497-7504
P577publication date1999-09-01
P1433published inJournal of VirologyQ1251128
P1476titleExpression of noncovalent hepatitis C virus envelope E1-E2 complexes is not required for the induction of antibodies with neutralizing properties following DNA immunization
P478volume73

Reverse relations

cites work (P2860)
Q36065682A candidate DNA vaccine elicits HCV specific humoral and cellular immune responses
Q29048140Binding of the hepatitis C virus E2 glycoprotein to CD81 is strain specific and is modulated by a complex interplay between hypervariable regions 1 and 2.
Q81319818Characterization of the immune response to DNA vaccination strategies for schistosomiasis candidate antigen, Sm-p80 in the baboon
Q27488724Conserved peptides within the E2 region of Hepatitis C virus induce humoral and cellular responses in goats
Q34552781Control of heterologous hepatitis C virus infection in chimpanzees is associated with the quality of vaccine-induced peripheral T-helper immune response
Q36308565DNA immunization with fusion genes encoding different regions of hepatitis C virus E2 fused to the gene for hepatitis B surface antigen elicits immune responses to both HCV and HBV
Q35105726Development of a hepatitis C virus vaccine
Q27469682Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates
Q27470000Genetic immunization of wild-type and hepatitis C virus transgenic mice reveals a hierarchy of cellular immune response and tolerance induction against hepatitis C virus structural proteins
Q57160237Hepatitis C vaccines
Q40166844Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies
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Q40468610West Nile premembrane-envelope genetic vaccine encoded as a chimera containing the transmembrane and cytoplasmic domains of a lysosome-associated membrane protein: increased cellular concentration of the transgene product, targeting to the MHC II co
Q73549448[Molecular biology of hepatitis C virus: implications for the development of new therapies and prophylactic vaccine]

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