Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities.

scientific article published on May 1994

Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID236792
P698PubMed publication ID7512157

P50authorBernard MossQ822617
P2093author name stringPeterson J
Broder CC
Earl PL
Chakrabarti S
Long D
Doms RW
Lee SA
P2860cites workMultimeric CD4 binding exhibited by human and simian immunodeficiency virus envelope protein dimersQ24630280
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymeraseQ27860943
Folding and assembly of viral membrane proteinsQ27865318
Complete nucleotide sequence of the AIDS virus, HTLV-IIIQ28259080
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoproteinQ28646759
Identification of the fusion peptide of primate immunodeficiency virusesQ28646799
Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1Q28646812
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAVQ28646817
The structure and function of the hemagglutinin membrane glycoprotein of influenza virusQ29618354
A general model for the transmembrane proteins of HIV and other retrovirusesQ30395640
Monoclonal Antibodies to the Extracellular Domain of HIV-1IIIB gp160 that Neutralize Infectivity, Block Binding to CD4, and React with Diverse IsolatesQ30778843
Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzeesQ33582665
Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.Q33685950
Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoproteinQ34097650
A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cellsQ42802044
Rat monoclonal antibodies to nonoverlapping epitopes of human immunodeficiency virus type 1 gp120 block CD4 binding in VitroQ43917849
B Cell Epitope Mapping of Human Immunodeficiency Virus Envelope Glycoproteins with Long (19- to 36-residue) Synthetic PeptidesQ43950591
Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV.Q44021595
A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activityQ44119196
HIV requires multiple gp120 molecules for CD4-mediated infectionQ44171806
Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoproteinQ44509170
Immunogenicity and Epitope Mapping of a Recombinant Soluble gp160 of the Human Immunodeficiency Virus Type 1 Envelope GlycoproteinQ44830160
Antibody Epitopes Sensitive to the State of Human Immunodeficiency Virus Type 1 gp41 Oligomerization Map to a Putative α-Helical RegionQ45237075
Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processingQ45252128
Epitopes of human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins recognized by antibodies in the sera of HIV-1-infected individualsQ45859839
Confronting the hypervariability of an immunodominant epitope eliciting virus neutralizing antibodies from the envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1)Q45860192
A new solid-state reagent to iodinate proteins. I. Conditions for the efficient labeling of antiserumQ46622394
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.Q48378749
Production of human monoclonal antibodies specific for conformational and linear non-V3 epitopes of gp120.Q55241600
Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene.Q55244821
Discontinuous epitopes on gp120 important in HIV-1 neutralizationQ67465908
Comparative immunogenicity of gp120-derived proteins and their induction of anti-V3 loop region antibodiesQ67802612
Two major groups of neutralizing anti-gp120 antibodies exist in HIV-infected individuals. Evidence for epitope diversity around the CD4 attachment siteQ67897903
Restriction of serum antibody reactivity to the V3 neutralizing domain of HIV gp120 with progression to AIDSQ68181056
Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120Q72067428
Principal neutralizing domain of the human immunodeficiency virus type 1 envelope proteinQ34301897
A conserved region at the COOH terminus of human immunodeficiency virus gp120 envelope protein contains an immunodominant epitopeQ34614992
Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteinsQ35076867
Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humansQ36641374
CD4 molecules with a diversity of mutations encompassing the CDR3 region efficiently support human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion.Q36641527
Analysis of the cross-reactive anti-gp120 antibody population in human immunodeficiency virus-infected asymptomatic individualsQ36641676
Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboonsQ36655953
Neutralization of HIV‐1: a paradox of humoral proportionsQ36661766
Folding, interaction with GRP78-BiP, assembly, and transport of the human immunodeficiency virus type 1 envelope proteinQ36684443
Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibodyQ36687562
Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia virusesQ36687749
Variant-specific monoclonal and group-specific polyclonal human immunodeficiency virus type 1 neutralizing antibodies raised with synthetic peptides from the gp120 third variable domain.Q36694332
gp160, the envelope glycoprotein of human immunodeficiency virus type 1, is a dimer of 125-kilodalton subunits stabilized through interactions between their gp41 domainsQ36701542
Oligomeric organization of gp120 on infectious human immunodeficiency virus type 1 particlesQ36793670
Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor bindingQ36795606
Removal of cryptic poxvirus transcription termination signals from the human immunodeficiency virus type 1 envelope gene enhances expression and immunogenicity of a recombinant vaccinia virus.Q36806386
Identification of human immunodeficiency virus envelope gene sequences influencing viral entry into CD4-positive HeLa cells, T-leukemia cells, and macrophagesQ36820658
A predominant group-specific neutralizing epitope of human immunodeficiency virus type 1 maps to residues 342 to 511 of the envelope glycoprotein gp120.Q36821056
Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibodyQ36821885
Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1Q36828367
Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitopeQ36869394
Expression of membrane-associated and secreted variants of gp160 of human immunodeficiency virus type 1 in vitro and in continuous cell linesQ36872227
Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivityQ36873079
Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.Q36881981
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibodyQ37399845
Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibodyQ37603996
A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.Q37634237
Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoproteinQ37675018
Protein oligomerization in the endoplasmic reticulumQ38737584
Regulation of protein export from the endoplasmic reticulumQ39544463
Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virions: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralization by soluble CD4.Q40059306
Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibodyQ40062738
Mutational analysis of the assembly domain of the HIV-1 envelope glycoproteinQ41544160
Topogenic analysis of the human immunodeficiency virus type 1 envelope glycoprotein, gp160, in microsomal membranesQ41562736
Secretion of a truncated form of the human immunodeficiency virus type 1 envelope glycoproteinQ41570066
Identification of human immunodeficiency virus type 1 glycoprotein gp120/gp41 interacting sites by the idiotypic mimicry of two monoclonal antibodies.Q41588189
Generation and characterization of a human monoclonal antibody that neutralizes diverse HIV-1 isolates in vitroQ41643892
An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infectionQ41679452
The human immunodeficiency virus type 1 envelope glycoprotein precursor acquires aberrant intermolecular disulfide bonds that may prevent normal proteolytic processingQ41712188
Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120Q42129803
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
monoclonal antibodyQ422248
P304page(s)3015-3026
P577publication date1994-05-01
P1433published inJournal of VirologyQ1251128
P1476titleNative oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities
P478volume68

Reverse relations

cites work (P2860)
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