Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection

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Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection is …
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scholarly articleQ13442814

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P819ADS bibcode2009PNAS..10614138S
P356DOI10.1073/PNAS.0906467106
P932PMC publication ID2729033
P698PubMed publication ID19666557
P5875ResearchGate publication ID26728435

P50authorFernando Queiroz CunhaQ38330464
Erna G. KroonQ40456670
Mauro M TeixeiraQ43261431
P2093author name stringDanielle G Souza
Caio T Fagundes
Daniela Sachs
Flavio A Amaral
Alena Atrasheuskaya
Eugenij Bukin
George Ignatyev
Adriano L Souza
Lirlandia P Sousa
Rafael S Souza
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Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitisQ28345121
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Anti-TNF antibody treatment reduces mortality in experimental dengue virus infectionQ33346586
A cascade of cytokines mediates mechanical inflammatory hypernociception in mice.Q33819799
Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processesQ35621992
Rodent models for the study of therapy against flavivirus infectionsQ35867772
Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptorQ36400935
Interferon-dependent immunity is essential for resistance to primary dengue virus infection in mice, whereas T- and B-cell-dependent immunity are less criticalQ36510607
Wild dengue virus types 1, 2 and 3 viremia in rhesus monkeysQ39011713
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Early clinical and laboratory indicators of acute dengue illnessQ40647872
A higher production of platelet activating factor in ex vivo heterologously secondary dengue-2 virus infectionsQ40690200
Role of PAF receptors during intestinal ischemia and reperfusion injury. A comparative study between PAF receptor-deficient mice and PAF receptor antagonist treatmentQ41886673
Inhibition by CV-3988 of the binding of [3H]-platelet activating factor (PAF) to the plateletQ42204871
Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptorQ44223906
UK-74,505, a novel and selective PAF antagonist, exhibits potent and long lasting activity in vivoQ46753689
Dengue: defining protective versus pathologic immunityQ56793103
Experimental Trypanosoma cruzi infection in platelet-activating factor receptor-deficient miceQ57034251
Platelet activating factor receptor-deficient mice present delayed interferon-γ upregulation and high susceptibility to Leishmania amazonensis infectionQ58857645
A lethal role of platelet activating factor in anaphylactic shock in miceQ70363804
Effect of a novel potent platelet-activating factor antagonist, modipafant, in clinical asthmaQ72204971
Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study GroupQ73117996
Signaling via platelet-activating factor receptors accounts for the impairment of neutrophil migration in polymicrobial sepsisQ79834671
P433issue33
P407language of work or nameEnglishQ1860
P921main subjectpathogenesisQ372016
Dengue virusQ476209
modulation by virus of host processQ14818042
P304page(s)14138-43
P577publication date2009-08-18
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleEssential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection
P478volume106

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