Paf1p YBR279W

fungal protein found in Saccharomyces cerevisiae S288c

Paf1p YBR279W is …
instance of (P31):
proteinQ8054

sublass of (P279):
proteinQ8054

External links are
P705Ensembl protein IDYBR279W
P637RefSeq protein IDNP_009838
P3406Saccharomyces Genome Database IDS000000483
P352UniProt protein IDP38351

P682biological processnegative regulation of transcription by RNA polymerase IIQ14633878
regulation of transcription, DNA-templatedQ14633883
transcription, DNA-templatedQ14763010
regulation of transcription by RNA polymerase IIQ14852032
rRNA processingQ14877433
transcription elongation from RNA polymerase II promoterQ14878260
regulation of transcription involved in G1/S transition of mitotic cell cycleQ14902236
transcription by RNA polymerase IQ14908087
transcription elongation from RNA polymerase I promoterQ14908089
histone modificationQ14911658
negative regulation of DNA recombinationQ14911686
DNA-templated transcription, terminationQ15311571
mRNA 3'-end processingQ21100337
positive regulation of transcription elongation from RNA polymerase II promoterQ21100359
regulation of histone H3-K4 methylationQ21101533
rDNA heterochromatin assemblyQ21105456
positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residuesQ21116336
global genome nucleotide-excision repairQ21973809
regulation of transcription-coupled nucleotide-excision repairQ22244218
regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residuesQ22245319
regulation of histone H2B ubiquitinationQ22245369
regulation of histone H2B conserved C-terminal lysine ubiquitinationQ22245370
positive regulation of histone H3-K36 trimethylationQ22245414
positive regulation of transcription elongation from RNA polymerase I promoterQ22253792
sno(s)RNA 3'-end processingQ22280666
snoRNA transcription by RNA polymerase IIQ22280980
P681cell componentnucleusQ40260
nucleoplasmQ14817956
Cdc73/Paf1 complexQ21109941
P702encoded byPAF1Q27545767
P703found in taxonSaccharomyces cerevisiae S288cQ27510868
P680molecular functionprotein bindingQ167149
chromatin bindingQ14817976
RNA polymerase II complex bindingQ21105695
RNA polymerase II C-terminal domain phosphoserine bindingQ21468848
RNA polymerase II general transcription initiation factor activityQ54809672
P361part ofRNA polymerase II associated factor Paf1Q24783962

Reverse relations

main subject (P921)
Q27934649A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation
Q27940291A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling
Q27934434A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast.
Q27935522Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme
Q27933282Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex
Q27936986Direct Bre1-Paf1 complex interactions and RING finger-independent Bre1-Rad6 interactions mediate histone H2B ubiquitylation in yeast
Q27933085Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.
Q27934457Diverse roles of RNA polymerase II-associated factor 1 complex in different subpathways of nucleotide excision repair
Q27936758Effectors of lysine 4 methylation of histone H3 in Saccharomyces cerevisiae are negative regulators of PHO5 and GAL1-10.
Q27931099Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation
Q27934996Exchange of RNA polymerase II initiation and elongation factors during gene expression in vivo
Q27936952Molecular evidence indicating that the yeast PAF complex is required for transcription elongation
Q27934234Mpk1 MAPK association with the Paf1 complex blocks Sen1-mediated premature transcription termination.
Q27932580Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex
Q27938071Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes
Q27933049Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization
Q27935078The Paf1 complex has functions independent of actively transcribing RNA polymerase II.
Q27940017The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p
Q27931337The Paf1 complex is required for efficient transcription elongation by RNA polymerase I
Q27930884The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation
Q27933848The Paf1 complex physically and functionally associates with transcription elongation factors in vivo
Q27935853The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II
Q90123113The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy
Q27933464The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.
Q27937468The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.
Q27935965The requirements for COMPASS and Paf1 in transcriptional silencing and methylation of histone H3 in Saccharomyces cerevisiae
Q90003148Yeast PAF1 complex counters the pol III accumulation and replication stress on the tRNA genes

Q107314773PAF1 complexhas part(s)P527
Q27545767PAF1encodesP688