| scholarly article | Q13442814 |
| P2093 | author name string | J A Tainer | |
| Y Guan | |||
| R P Cunningham | |||
| B J Haas | |||
| D J Hosfield | |||
| P2860 | cites work | Instability and decay of the primary structure of DNA | Q22122361 |
| Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes | Q24293149 | ||
| Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions | Q24315065 | ||
| Conserved domains in DNA repair proteins and evolution of repair systems | Q24548678 | ||
| Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 | ||
| High-resolution (1.5 A) crystal structure of phospholipase C from Bacillus cereus | Q27690743 | ||
| Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP | Q27729369 | ||
| Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA | Q27729896 | ||
| Electrostatics and diffusion of molecules in solution: simulations with the University of Houston Brownian dynamics program | Q61773837 | ||
| Crystal structures of phosphate, iodide and iodate-inhibited phospholipase C from Bacillus cereus and structural investigations of the binding of reaction products and a substrate analogue | Q68136580 | ||
| Abasic sites stimulate double-stranded DNA cleavage mediated by topoisomerase II. DNA lesions as endogenous topoisomerase II poisons | Q72036713 | ||
| DNA polymerase beta: multiple conformational changes in the mechanism of catalysis | Q73718102 | ||
| Structure and function of the multifunctional DNA-repair enzyme exonuclease III | Q27730409 | ||
| A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA | Q27733802 | ||
| Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism | Q27742804 | ||
| Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision | Q27765744 | ||
| Raster3D Version 2.0. A program for photorealistic molecular graphics | Q27860485 | ||
| Rapid automated molecular replacement by evolutionary search | Q27860711 | ||
| Crystallographic R factor refinement by molecular dynamics | Q27860942 | ||
| XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density | Q27861034 | ||
| The CCP4 suite: programs for protein crystallography | Q27861090 | ||
| Automated MAD and MIR structure solution | Q27861114 | ||
| Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV | Q27930192 | ||
| Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence data | Q28188248 | ||
| Assessment of phase accuracy by cross validation: the free R value. Methods and applications | Q29617259 | ||
| Repair of oxidative damage to DNA: enzymology and biology | Q29618065 | ||
| The structure and evolution of alpha/beta barrel proteins | Q30193545 | ||
| The evolution of alpha/beta barrel enzymes | Q30195850 | ||
| Envisioning the molecular choreography of DNA base excision repair | Q33536610 | ||
| Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. | Q33889451 | ||
| Endonuclease IV of Escherichia coli is induced by paraquat | Q34622611 | ||
| Regulation of eukaryotic abasic endonucleases and their role in genetic stability | Q34638790 | ||
| Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease | Q35686019 | ||
| Escherichia coli proteins inducible by oxidative stress mediated by the superoxide radical | Q36175014 | ||
| Nucleotide sequence of the xth gene of Escherichia coli K-12 | Q36217884 | ||
| Nucleotide sequence of the nfo gene of Escherichia coli K-12. | Q36221694 | ||
| The Caenorhabditis elegans gene CeAPN1 encodes a homolog of Escherichia coli and yeast apurinic/apyrimidinic endonuclease | Q36839109 | ||
| Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli | Q37403076 | ||
| Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV. | Q38306943 | ||
| Apurinic sites as mutagenic intermediates | Q39492837 | ||
| Cleavage of single- and double-stranded DNAs containing an abasic residue by Escherichia coli exonuclease III (AP endonuclease VI) | Q39718150 | ||
| Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation | Q40640344 | ||
| DNA glycosylases | Q41481681 | ||
| DNA glycosylases in the base excision repair of DNA | Q41532551 | ||
| Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway. | Q41687087 | ||
| The apurinic-apyrimidinic endonuclease IV family of DNA repair enzymes | Q41717165 | ||
| The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites | Q42631836 | ||
| Faster superoxide dismutase mutants designed by enhancing electrostatic guidance | Q45965859 | ||
| Zinc enzymes. | Q47829387 | ||
| Schizosaccharomyces pombe apn1 encodes a homologue of the Escherichia coli endonuclease IV family of DNA repair proteins | Q48039252 | ||
| Crystal structure of phospholipase C from Bacillus cereus complexed with a substrate analog. | Q52387994 | ||
| Improved Fourier coefficients for maps using phases from partial structures with errors | Q56877556 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 397-408 | |
| P577 | publication date | 1999-08-06 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis | |
| P478 | volume | 98 |
| Q27640002 | A base-flipping mechanism for the T4 phage beta-glucosyltransferase and identification of a transition-state analog |
| Q39306724 | A kinetic mechanism of repair of DNA containing α-anomeric deoxyadenosine by human apurinic/apyrimidinic endonuclease 1. |
| Q64390396 | A sequence-specific DNA glycosylase mediates restriction-modification in Pyrococcus abyssi |
| Q52337930 | A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping. |
| Q28143939 | Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means |
| Q30360256 | Accelerated Molecular Dynamics Simulations with the AMOEBA Polarizable Force Field on Graphics Processing Units |
| Q33941847 | AdoMet-dependent methylation, DNA methyltransferases and base flipping |
| Q40480353 | African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages. |
| Q38104337 | Alternative excision repair pathways |
| Q43863362 | Alternative nucleotide incision repair pathway for oxidative DNA damage |
| Q56256560 | Base Flipping |
| Q34883473 | Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii |
| Q34283911 | Base excision repair in a network of defence and tolerance |
| Q34374847 | Base excision repair. |
| Q35214509 | Biochemical functional predictions for protein structures of unknown or uncertain function |
| Q42603204 | Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus |
| Q33649960 | Biological properties of single chemical-DNA adducts: a twenty year perspective |
| Q34402463 | Calcium inhibition of ribonuclease H1 two-metal ion catalysis |
| Q47612525 | Catalysing new reactions during evolution: economy of residues and mechanism |
| Q38348799 | Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases |
| Q44223853 | Characterization of an endonuclease IV 3'-5' exonuclease activity |
| Q41883369 | Characterization of class II apurinic/apyrimidinic endonuclease activities in the human malaria parasite, Plasmodium falciparum |
| Q36535036 | Chemical synthesis of oligonucleotides containing damaged bases for biological studies |
| Q39646018 | Clue to damage recognition by UvrB: residues in the beta-hairpin structure prevent binding to non-damaged DNA. |
| Q27676022 | Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes |
| Q37336997 | Correlation of bistranded clustered abasic DNA lesion processing with structural and dynamic DNA helix distortion |
| Q27667656 | Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity |
| Q27639347 | Crystal structure ofBacillus subtilis ioli shows endonuclase IV fold with altered Zn binding |
| Q58132113 | DNA Mechanics and Topology |
| Q27676629 | DNA Sequence Context Conceals α-Anomeric Lesions |
| Q27650316 | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV |
| Q37573870 | DNA base repair--recognition and initiation of catalysis |
| Q44954472 | DNA binding and nucleotide flipping by the human DNA repair protein AGT. |
| Q36012002 | DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy |
| Q92075148 | DNA complexes with human apurinic/apyrimidinic endonuclease 1: structural insights revealed by pulsed dipolar EPR with orthogonal spin labeling |
| Q34367279 | DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. |
| Q27649103 | DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics |
| Q34042848 | DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences |
| Q27621279 | DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected] |
| Q52651876 | Defect-facilitated buckling in supercoiled double-helix DNA. |
| Q50067499 | Detection of low-abundance point mutations by competitive strand assisted endonuclease IV signal amplification system |
| Q34627873 | Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines |
| Q40337429 | Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases |
| Q43028137 | Distinct catalytic activity and in vivo roles of the ExoIII and EndoIV AP endonucleases from Sulfolobus islandicus |
| Q53530457 | Dual role for Zn2+ in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease. |
| Q79120787 | Effective detection of remote homologues by searching in sequence dataset of a protein domain fold |
| Q43882514 | Effects of a guanine-derived formamidopyrimidine lesion on DNA replication: translesion DNA synthesis, nucleotide insertion, and extension kinetics |
| Q44005234 | ElaC encodes a novel binuclear zinc phosphodiesterase |
| Q34926905 | Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage |
| Q48364619 | Endonuclease IV homolog from Dictyostelium discoideum: sequencing and functional expression in AP endonuclease-deficient Escherichia coli |
| Q28645615 | Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch |
| Q44429270 | Enzymology of base excision repair in the hyperthermophilic archaeon Pyrobaculum aerophilum |
| Q35026369 | Enzymology of the repair of free radicals-induced DNA damage |
| Q43964510 | Escherichia coli apurinic-apyrimidinic endonucleases enhance the turnover of the adenine glycosylase MutY with G:A substrates |
| Q93169828 | Evolution of endonuclease IV protein family: an in silico analysis |
| Q43966281 | Flipping duplex DNA inside out: a double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase |
| Q34490694 | Forespore-specific expression of Bacillus subtilis yqfS, which encodes type IV apurinic/apyrimidinic endonuclease, a component of the base excision repair pathway |
| Q34475702 | Formation and repair of tobacco carcinogen-derived bulky DNA adducts |
| Q33888410 | High efficiency detection of bi-stranded abasic clusters in gamma-irradiated DNA by putrescine |
| Q42261855 | High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center. |
| Q58006768 | Hybrid QM/MM Simulations of Enzyme-Catalyzed DNA Repair Reactions |
| Q28206067 | Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide |
| Q27679274 | Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases |
| Q34320204 | Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites |
| Q47415103 | Investigation of the cyclobutane pyrimidine dimer (CPD) photolyase DNA recognition mechanism by NMR analyses |
| Q27653933 | Involvement of a carboxylated lysine in UV damage endonuclease |
| Q24814686 | Isolation of a small molecule inhibitor of DNA base excision repair. |
| Q57804146 | Kinetic Pathway of Torsional DNA Buckling |
| Q47915615 | Mechanisms of subzero growth in the cryophile Planococcus halocryophilus determined through proteomic analysis |
| Q40707180 | Metabolism of carcinogenic urethane to nitric oxide is involved in oxidative DNA damage |
| Q27639991 | Metal ions and phosphate binding in the H-N-H motif: Crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions |
| Q44511100 | Modulation of the 3'-->5'-exonuclease activity of human apurinic endonuclease (Ape1) by its 5'-incised Abasic DNA product |
| Q44840270 | Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1. |
| Q38300220 | Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence |
| Q42532919 | Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease. |
| Q37808947 | One is enough: insights into the two-metal ion nuclease mechanism from global analysis and computational studies |
| Q34367287 | Potential double-flipping mechanism by E. coli MutY. |
| Q42199068 | Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology |
| Q33576446 | Purification, crystallization and preliminary crystallographic analysis of a thermostable endonuclease IV from Thermotoga maritima |
| Q27620825 | Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex |
| Q38005951 | Recognition of damaged DNA: structure and dynamic markers |
| Q38361321 | Role of base flipping in specific recognition of damaged DNA by repair enzymes. |
| Q34109980 | Role of the Nfo (YqfS) and ExoA apurinic/apyrimidinic endonucleases in protecting Bacillus subtilis spores from DNA damage |
| Q36610269 | Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans |
| Q42528262 | Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. |
| Q40900534 | Solution structure of a nitrous acid induced DNA interstrand cross-link. |
| Q27634132 | Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformation |
| Q42922063 | Stress and survival of aging Escherichia coli rpoS colonies |
| Q50720187 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. |
| Q34249556 | Structure and function of TatD exonuclease in DNA repair |
| Q34165036 | Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors. |
| Q37044560 | Structure and mechanism for DNA lesion recognition |
| Q27620618 | Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus |
| Q37168010 | Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase |
| Q27652487 | Structure of L-Xylulose-5-Phosphate 3-Epimerase (UlaE) from the Anaerobic L-Ascorbate Utilization Pathway of Escherichia coli: Identification of a Novel Phosphate Binding Motif within a TIM Barrel Fold |
| Q27664321 | Structure of the endonuclease IV homologue fromThermotoga maritimain the presence of active-site divalent metal ions |
| Q27684614 | Structure ofD-tagatose 3-epimerase-like protein fromMethanocaldococcus jannaschii |
| Q44931288 | Structure-based analysis of the metal-dependent mechanism of H-N-H endonucleases |
| Q27323929 | Structure-based function prediction of uncharacterized protein using binding sites comparison |
| Q49434468 | Supercoiling DNA Locates Mismatches |
| Q42546307 | Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine. |
| Q27640195 | Synthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3'-phosphoglycolate, 5'-phosphate gapped lesion |
| Q34285514 | Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity. |
| Q38326948 | The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins |
| Q43015372 | The DNA Exonucleases of Escherichia coli |
| Q38206321 | The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once |
| Q34390593 | The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. |
| Q40695077 | The major role of human AP-endonuclease homolog Apn2 in repair of abasic sites in Schizosaccharomyces pombe |
| Q33941852 | The structural basis of damaged DNA recognition and endonucleolytic cleavage for very short patch repair endonuclease |
| Q33600991 | The zinc ion in the HNH motif of the endonuclease domain of colicin E7 is not required for DNA binding but is essential for DNA hydrolysis |
| Q60934914 | Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA |
| Q38335880 | Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta. |
| Q42632884 | Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. |
| Q35001867 | Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes. |
| Q27675397 | UV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesions |
| Q34479493 | Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles. |
| Q35607001 | Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV |
| Q34983433 | Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells |
| Q30336320 | Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins. |
| Q30418666 | Using surface-bound rubidium ions for protein phasing |
| Q35921882 | YqfS from Bacillus subtilis is a spore protein and a new functional member of the type IV apurinic/apyrimidinic-endonuclease family |
| Q34214026 | Zinc and the gene |
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