A kinetic mechanism of repair of DNA containing α-anomeric deoxyadenosine by human apurinic/apyrimidinic endonuclease 1.

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A kinetic mechanism of repair of DNA containing α-anomeric deoxyadenosine by human apurinic/apyrimidinic endonuclease 1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C6MB00511J
P8608Fatcat IDrelease_443frlwxhffmbbzwolxmokb7yy
P698PubMed publication ID27722620

P50authorOlga S. FedorovaQ54327407
P2093author name stringN A Timofeyeva
P2860cites workInstability and decay of the primary structure of DNAQ22122361
Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysisQ27619456
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]Q27621279
DNA Sequence Context Conceals α-Anomeric LesionsQ27676629
Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleasesQ27679274
Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the meansQ28143939
Hypoxia--a key regulatory factor in tumour growthQ29547318
Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinaseQ29617738
Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescenceQ31914649
Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathwaysQ34017825
DNA damage processing by human 8-oxoguanine-DNA glycosylase mutants with the occluded active site.Q37213864
Conformational selection or induced fit: a flux description of reaction mechanismQ37310586
Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV.Q38306943
Conformational dynamics of human AP endonuclease in base excision and nucleotide incision repair pathwaysQ38356386
Genetic toxicology of oxygenQ38683020
Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectorsQ39719038
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway.Q40695131
Conformational transitions in human AP endonuclease 1 and its active site mutant during abasic site repair.Q43006628
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase betaQ44130577
Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV.Q44819425
Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleasesQ45165833
P433issue11
P304page(s)3435-3446
P577publication date2016-10-01
P1433published inMolecular BioSystemsQ3319467
P1476titleA kinetic mechanism of repair of DNA containing α-anomeric deoxyadenosine by human apurinic/apyrimidinic endonuclease 1
P478volume12

Reverse relations

Q57454231Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathwaycites workP2860