| scholarly article | Q13442814 |
| P50 | author | Alexander Ishchenko | Q57073174 |
| P2093 | author name string | Hiroshi Ide | |
| Laurent Gros | |||
| Murat K Saparbaev | |||
| Rhoderick H Elder | |||
| P2860 | cites work | Instability and decay of the primary structure of DNA | Q22122361 |
| Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism | Q24291085 | ||
| Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes | Q24293149 | ||
| The characterization of a mammalian DNA structure-specific endonuclease | Q24336672 | ||
| Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). | Q24532243 | ||
| Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme | Q24555669 | ||
| Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants | Q24629413 | ||
| DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected] | Q27621279 | ||
| Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV | Q27930192 | ||
| The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast | Q27931578 | ||
| Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue | Q28279728 | ||
| Processing of DNA base damage by DNA polymerases. Dihydrothymine and beta-ureidoisobutyric acid as models for instructive and noninstructive lesions | Q28334662 | ||
| Quality control by DNA repair | Q28608962 | ||
| Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals | Q28610604 | ||
| Hypoxia--a key regulatory factor in tumour growth | Q29547318 | ||
| DNA replication fidelity | Q29616841 | ||
| Repair of oxidative damage to DNA: enzymology and biology | Q29618065 | ||
| Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. | Q33182233 | ||
| Going APE over ref-1. | Q34053099 | ||
| Keynote: past, present, and future aspects of base excision repair | Q34367323 | ||
| The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. | Q34390593 | ||
| The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains | Q34878594 | ||
| Two rotameric forms of open ring 7-methylguanine are present in alkylated polynucleotides | Q35291535 | ||
| Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants | Q35624116 | ||
| Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA | Q35790359 | ||
| An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site | Q35926837 | ||
| Endonuclease IV (nfo) mutant of Escherichia coli | Q36261707 | ||
| Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli | Q36309404 | ||
| Endogenous oxidative damage of deoxycytidine in DNA. | Q36951566 | ||
| The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. | Q37377727 | ||
| 1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase | Q38289103 | ||
| Alpha-deoxyadenosine, a major anoxic radiolysis product of adenine in DNA, is a substrate for Escherichia coli endonuclease IV. | Q38306943 | ||
| Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease | Q38340919 | ||
| Genetic toxicology of oxygen | Q38683020 | ||
| Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors | Q39719038 | ||
| Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation | Q40640344 | ||
| The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites | Q42631836 | ||
| Alternative nucleotide incision repair pathway for oxidative DNA damage | Q43863362 | ||
| Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts. | Q44195377 | ||
| The exonuclease activity of human apurinic/apyrimidinic endonuclease (APE1). Biochemical properties and inhibition by the natural dinucleotide Gp4G. | Q44353890 | ||
| The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death | Q44416563 | ||
| Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV. | Q46820327 | ||
| Yields of radiation-induced base products in DNA: effects of DNA conformation and gassing conditions. | Q51728576 | ||
| A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. | Q52182528 | ||
| Radiation-induced DNA damage and its repair. | Q54766327 | ||
| Formation of alpha-deoxyadenosine in polydeoxynucleotides exposed to ionizing radiation under anoxic conditions | Q68732550 | ||
| Production of dihydrothymidine stereoisomers in DNA by gamma-irradiation | Q69613609 | ||
| In vitro gamma irradiation of DNA: identification of radioinduced chemical modifications of the adenine moiety | Q72141984 | ||
| Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR | Q72875857 | ||
| Purification and characterization of an apurinic/apyrimidinic endonuclease from HeLa cells | Q72883404 | ||
| Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5 | Q73314976 | ||
| Deletion analysis of human AP-endonuclease: minimum sequence required for the endonuclease activity | Q74390472 | ||
| Rapid dissociation of human apurinic endonuclease (Ape1) from incised DNA induced by magnesium | Q77520920 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 73-81 | |
| P577 | publication date | 2004-01-02 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway | |
| P478 | volume | 32 |
| Q39306724 | A kinetic mechanism of repair of DNA containing α-anomeric deoxyadenosine by human apurinic/apyrimidinic endonuclease 1. |
| Q36751371 | A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification |
| Q35870045 | APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1. |
| Q46754854 | Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2. |
| Q24304919 | Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1). |
| Q35955906 | Base excision repair: contribution to tumorigenesis and target in anticancer treatment paradigms |
| Q36303574 | Capturing snapshots of APE1 processing DNA damage. |
| Q58778800 | Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori |
| Q33649473 | Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts. |
| Q35131211 | Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L |
| Q28306117 | Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates |
| Q38356386 | Conformational dynamics of human AP endonuclease in base excision and nucleotide incision repair pathways |
| Q42737383 | Crystallization and preliminary X-ray analysis of human endonuclease 1 (APE1) in complex with an oligonucleotide containing a 5,6-dihydrouracil (DHU) or an alpha-anomeric 2'-deoxyadenosine (alphadA) modified base |
| Q48443933 | Cyclohexane produces behavioral deficits associated with astrogliosis and microglial reactivity in the adult hippocampus mouse brain |
| Q27650316 | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV |
| Q37573870 | DNA base repair--recognition and initiation of catalysis |
| Q43045076 | DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides. |
| Q34848804 | Dual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expression |
| Q37727678 | Epimeric 2-deoxyribose lesions: Products from the improper chemical repair of 2-deoxyribose radicals |
| Q33670045 | FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells |
| Q34475702 | Formation and repair of tobacco carcinogen-derived bulky DNA adducts |
| Q33859467 | Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damage |
| Q28475182 | Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity |
| Q38310377 | High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs. |
| Q34517201 | Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway |
| Q24812717 | Human AP endonuclease suppresses DNA mismatch repair activity leading to microsatellite instability. |
| Q37512952 | Human apurinic/apyrimidinic endonuclease 1. |
| Q34055705 | Human base excision repair creates a bias toward -1 frameshift mutations |
| Q39942445 | Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1. |
| Q34904605 | Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry |
| Q37149762 | Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family. |
| Q35599868 | Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties |
| Q27679274 | Insight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases |
| Q35865301 | Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences |
| Q24814686 | Isolation of a small molecule inhibitor of DNA base excision repair. |
| Q58691387 | Kinetic Features of 3'-5' Exonuclease Activity of Human AP-Endonuclease APE1 |
| Q34017825 | Lys98 substitution in human AP endonuclease 1 affects the kinetic mechanism of enzyme action in base excision and nucleotide incision repair pathways |
| Q37826346 | Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair |
| Q49300222 | Molecular snapshots of APE1 proofreading mismatches and removing DNA damage |
| Q24563901 | Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylase |
| Q31025778 | New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. |
| Q47143560 | Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication |
| Q34110759 | Nonspecific DNA binding and coordination of the first two steps of base excision repair |
| Q24793953 | Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins |
| Q36955832 | Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements. |
| Q36145393 | Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells |
| Q36744400 | Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice |
| Q24315064 | Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. |
| Q42528262 | Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. |
| Q34208966 | Small molecule inhibitors of DNA repair nuclease activities of APE1 |
| Q34333638 | Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C. |
| Q57454231 | Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway |
| Q27936279 | The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. |
| Q37684917 | The Fanconi anemia pathway promotes DNA glycosylase-dependent excision of interstrand DNA crosslinks |
| Q39115723 | The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease. |
| Q26777671 | The current state of eukaryotic DNA base damage and repair |
| Q60934914 | Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA |
| Q34479493 | Uncoupling of the base excision and nucleotide incision repair pathways reveals their respective biological roles. |
| Q34983433 | Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells |
| Q37151889 | Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress |
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