A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol

scientific article

A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol is …
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scholarly articleQ13442814

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P819ADS bibcode2007PNAS..104..814A
P356DOI10.1073/PNAS.0606648104
P8608Fatcat IDrelease_4whilvpqxjc4nm7bjhxkmjbsnu
P3181OpenCitations bibliographic resource ID4761140
P932PMC publication ID1783396
P698PubMed publication ID17210917
P5875ResearchGate publication ID6590308

P50authorSylvie DoubliéQ28323959
Susan S WallaceQ41886664
P2093author name stringMatthew Hogg
Mark A Rould
Pierre Aller
P2860cites workCloning and characterization of a functional human homolog of Escherichia coli endonuclease IIIQ24311942
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNAQ24531459
Preferential formation of (5S,6R)-thymine glycol for oligodeoxyribonucleotide synthesis and analysis of drug binding to thymine glycol-containing DNA.Q25257194
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
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Structure of the replicating complex of a pol alpha family DNA polymeraseQ27632340
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Preparation of selenomethionyl proteins for phase determinationQ27860869
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIIIQ28201222
Translesion synthesis by human DNA polymerase eta across thymine glycol lesionsQ28216674
Oxidative damage to DNA: relation to species metabolic rate and life spanQ33567378
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotidesQ34141563
Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damageQ34264083
Abasic sites from cytosine as termination signals for DNA synthesisQ35554949
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.Q35564216
Sequence-specific recognition of double helical nucleic acids by proteinsQ35987597
Thymine glycol lesions terminate chain elongation by DNA polymerase I in vitroQ36089095
Sequence dependence for bypass of thymine glycols in DNA by DNA polymerase IQ36089478
Excision repair of thymine glycols, urea residues, and apurinic sites in Escherichia coliQ36209696
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic siteQ37543875
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Acyclic and dideoxy terminator preferences denote divergent sugar recognition by archaeon and Taq DNA polymerasesQ39528240
Thymine lesions produced by ionizing radiation in double-stranded DNA.Q42225404
Identification of the cis-thymine glycol moiety in chemically oxidized and gamma-irradiated deoxyribonucleic acid by high-pressure liquid chromatography analysis.Q42270823
Processing of model single-strand breaks in phi X-174 RF transfecting DNA by Escherichia coli.Q54386327
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol.Q54462984
Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis.Q54658619
Oxidative damage in DNA. Lack of mutagenicity by thymine glycol lesions.Q54748389
The role of specific DNA base damages in the X-ray-induced inactivation of bacteriophage PM2Q62061136
Modeling and molecular mechanical studies of the cis-thymine glycol radiation damage lesion in DNAQ69441230
Template length, sequence context, and 3'-5' exonuclease activity modulate replicative bypass of thymine glycol lesions in vitroQ69596822
Molecular dynamics simulations of the effects of ring‐saturated thymine lesions on DNA structureQ72110191
Inducible repair of thymine ring saturation damage in phi X174 DNAQ72786180
Structure of a duplex DNA containing a thymine glycol residue in solutionQ73182586
Replication inhibition and miscoding properties of DNA templates containing a site-specific cis-thymine glycol or urea residueQ74644571
Synthesis of Thymine Glycol Containing Oligonucleotides from a Building Block with the Oxidized BaseQ88521254
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectthymineQ171973
P304page(s)814-8
P577publication date2007-01-16
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleA structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol
P478volume104