scholarly article | Q13442814 |
P50 | author | Susan S Wallace | Q41886664 |
P2093 | author name string | Jeffrey P Bond | |
Viswanath Bandaru | |||
Sirisha Sunkara | |||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Escherichia coli | Q25419 |
DNA damage | Q5205747 | ||
P304 | page(s) | 517-29 | |
P577 | publication date | 2002-07-17 | |
P1433 | published in | DNA Repair | Q3894086 |
P1476 | title | A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII | |
P478 | volume | 1 |
Q36701059 | 3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair |
Q27667498 | 5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases |
Q27670953 | A Crystallographic Study of the Role of Sequence Context in Thymine Glycol Bypass by a Replicative DNA Polymerase Serendipitously Sheds Light on the Exonuclease Complex |
Q39506181 | A Novel GT-Mismatch Binding Protein That Recognizes Strict DNA Sequences with High Affinity |
Q28219332 | A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue |
Q21558626 | A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma |
Q27641081 | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol |
Q36751371 | A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification |
Q36234156 | APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress. |
Q24563827 | Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity |
Q35037457 | Arabidopsis thaliana, a versatile model system for study of eukaryotic genome-maintenance functions |
Q57603139 | Array comparative genomic hybridisation testing in CHD |
Q34305503 | Association of polymorphisms in oxidative stress genes with clinical outcomes for bladder cancer treated with Bacillus Calmette-Guérin |
Q35886189 | Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA. |
Q28288115 | Base excision repair |
Q27025537 | Base excision repair and cancer |
Q42230093 | Base excision repair and the role of MUTYH |
Q36538373 | Base excision repair in physiology and pathology of the central nervous system |
Q36853499 | Base excision repair, aging and health span. |
Q34374847 | Base excision repair. |
Q29615373 | Base-excision repair of oxidative DNA damage |
Q27658074 | Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion site |
Q41718273 | Cadmium effects on DNA and protein metabolism in oyster (Crassostrea gigas) revealed by proteomic analyses |
Q90546786 | Cervical carcinoma risk associate with genetic polymorphisms of NEIL2 gene in Chinese population and its significance as predictive biomarker |
Q33649473 | Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts. |
Q37933191 | Chemistry and structural biology of DNA damage and biological consequences |
Q44454290 | Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells |
Q44486177 | Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases. |
Q92948154 | Computational and Experimental Druggability Assessment of Human DNA Glycosylases |
Q89977186 | Contributions of DNA Damage to Alzheimer's Disease |
Q37719258 | DNA glycosylases search for and remove oxidized DNA bases |
Q27642268 | DNA lesion recognition by the bacterial repair enzyme MutM |
Q43045076 | DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides. |
Q40586328 | DNA repair investigations using siRNA. |
Q44454284 | Decline of nuclear and mitochondrial oxidative base excision repair activity in late passage human diploid fibroblasts |
Q54457471 | Deoxyribophosphate lyase activity of mammalian endonuclease VIII-like proteins. |
Q47432231 | Differential effects of silver nanoparticles on DNA damage and DNA repair gene expression in Ogg1-deficient and wild type mice |
Q28239818 | Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions |
Q24650179 | Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells |
Q21558654 | Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine |
Q36713854 | Efficient removal of formamidopyrimidines by 8-oxoguanine glycosylases |
Q21558627 | Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma |
Q42686558 | Evaluation of oxidative stress markers in pathogenesis of primary open-angle glaucoma |
Q42674153 | Evidence for base excision repair of oxidative DNA damage in chloroplasts of Arabidopsis thaliana |
Q33635477 | Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines |
Q36559344 | Evolution in fast forward: a potential role for mutators in accelerating Staphylococcus aureus pathoadaptation |
Q35596477 | Exploiting base excision repair to improve therapeutic approaches for pancreatic cancer |
Q36044239 | Expression and purification of active mouse and human NEIL3 proteins. |
Q39018239 | Formation and processing of DNA damage substrates for the hNEIL enzymes |
Q47446317 | Formation and repair of DNA-protein crosslink damage. |
Q34514783 | Functional variants of the NEIL1 and NEIL2 genes and risk and progression of squamous cell carcinoma of the oral cavity and oropharynx |
Q37780480 | Functions of disordered regions in mammalian early base excision repair proteins |
Q33367810 | Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer |
Q27681153 | Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing |
Q30370866 | Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations |
Q37002577 | Genome-wide association study of serum selenium concentrations |
Q37247774 | Going ape as an approach to cancer therapeutics |
Q36728705 | Guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin induces mutations when bypassed by DNA polymerases and is a substrate for base excision repair |
Q26740627 | Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon Cancer |
Q39014392 | Hide and seek: How do DNA glycosylases locate oxidatively damaged DNA bases amidst a sea of undamaged bases? |
Q42130654 | Human DNA Glycosylase NEIL1's Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival |
Q24318591 | Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA |
Q24322513 | Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutant |
Q46335843 | Human cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomes |
Q36174152 | Human endonuclease VIII-like (NEIL) proteins in the giant DNA Mimivirus |
Q36079274 | Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair |
Q36341399 | Identification of DNA lesions using a third base pair for amplification and nanopore sequencing |
Q36645850 | Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight |
Q28279961 | Identification of a zinc finger domain in the human NEIL2 (Nei-like-2) protein |
Q57470790 | Identification of retinal homeobox (rax) gene-dependent genes by a microarray approach: the DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway |
Q35992170 | Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2. |
Q28268678 | Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species |
Q46684221 | Influence of Ogg1 repair on the genetic stability of ccc2 mutant of Saccharomyces cerevisiae chemically challenged with 4-nitroquinoline-1-oxide (4-NQO). |
Q46886711 | Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomes |
Q43176326 | Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA. |
Q34989590 | Interplay between DNA repair and inflammation, and the link to cancer |
Q91657262 | Isoforms of Base Excision Repair Enzymes Produced by Alternative Splicing |
Q36855635 | Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies |
Q34771368 | Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells |
Q35576447 | Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage |
Q36223869 | Mitochondrial DNA, base excision repair and neurodegeneration |
Q38573535 | Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts |
Q33858180 | Mutation versus repair: NEIL1 removal of hydantoin lesions in single-stranded, bulge, bubble, and duplex DNA contexts |
Q39979884 | Mutator phenotype of mammalian cells due to deficiency of NEIL1 DNA glycosylase, an oxidized base-specific repair enzyme |
Q83228165 | NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress |
Q36266557 | NEIL1 binding to DNA containing 2'-fluorothymidine glycol stereoisomers and the effect of editing |
Q24647462 | NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells |
Q41484741 | Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision |
Q38804981 | Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation. |
Q36139765 | Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation |
Q34362594 | Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context |
Q37439348 | Neil3 induced neurogenesis protects against prion disease during the clinical phase |
Q36853206 | Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage. |
Q26996127 | New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases |
Q47143560 | Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication |
Q33518545 | Nucleotide, cytogenetic and expression impact of the human chromosome 8p23.1 inversion polymorphism |
Q34805446 | Obesity and hepatosteatosis in mice with enhanced oxidative DNA damage processing in mitochondria |
Q41957575 | Oxanine DNA glycosylase activities in mammalian systems. |
Q62061093 | Oxidative DNA Glycosylases: Recipes from Cloning to Characterization |
Q36658399 | Oxidative DNA damage repair in mammalian cells: a new perspective |
Q37858347 | Oxidative genome damage and its repair in neurodegenerative diseases: function of transition metals as a double-edged sword |
Q35957287 | Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. |
Q36102804 | Phosphorylation Sites Identified in the NEIL1 DNA Glycosylase Are Potential Targets for the JNK1 Kinase. |
Q36914462 | Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1 |
Q37315825 | Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases. |
Q34685037 | Polymorphism of the DNA base excision repair genes in keratoconus |
Q41225003 | Pre-Replicative Repair of Oxidized Bases Maintains Fidelity in Mammalian Genomes: The Cowcatcher Role of NEIL1 DNA Glycosylase |
Q34675663 | Preferential repair of oxidized base damage in the transcribed genes of mammalian cells |
Q64388814 | Processing of N-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3 |
Q36955832 | Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements. |
Q35165256 | Profiling base excision repair glycosylases with synthesized transition state analogs |
Q36145393 | Psoralen-induced DNA adducts are substrates for the base excision repair pathway in human cells |
Q34376081 | RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1 |
Q33546272 | RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures |
Q35781828 | Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates. |
Q34306735 | Recent advances in the structural mechanisms of DNA glycosylases |
Q33672967 | Regulatory regions responsive to oxidative stress in the promoter of the human DNA glycosylase gene NEIL2. |
Q39000410 | Removal of oxidatively generated DNA damage by overlapping repair pathways |
Q28206447 | Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2 |
Q44195377 | Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts. |
Q37532110 | Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair |
Q39200289 | Repair of oxidatively induced DNA damage by DNA glycosylases: Mechanisms of action, substrate specificities and excision kinetics |
Q28570918 | Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair |
Q28082525 | Snaps and mends: DNA breaks and chromosomal translocations |
Q34121351 | Specific Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases |
Q37068680 | Stereoselective excision of thymine glycol from oxidatively damaged DNA. |
Q24648095 | Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress |
Q27676196 | Structural Characterization of Viral Ortholog of Human DNA Glycosylase NEIL1 Bound to Thymine Glycol or 5-Hydroxyuracil-containing DNA |
Q27675877 | Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA |
Q27656645 | Structural Characterization of a Viral NEIL1 Ortholog Unliganded and Bound to Abasic Site-containing DNA |
Q35189594 | Structural characterization of the Fpg family of DNA glycosylases |
Q27680235 | Structural investigation of a viral ortholog of human NEIL2/3 DNA glycosylases |
Q24811220 | Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility |
Q34077785 | Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases |
Q36952958 | Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1 |
Q37102321 | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair |
Q26851561 | The Fanconi anemia pathway and DNA interstrand cross-link repair |
Q37684917 | The Fanconi anemia pathway promotes DNA glycosylase-dependent excision of interstrand DNA crosslinks |
Q27021912 | The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage |
Q47139042 | The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure. |
Q35562087 | The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures |
Q21284159 | The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins |
Q37010194 | The RECQL4 protein, deficient in Rothmund-Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesions |
Q27657520 | The cis -(5 R ,6 S )-Thymine Glycol Lesion Occupies the Wobble Position When Mismatched with Deoxyguanosine in DNA |
Q24564283 | The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity |
Q37187941 | The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions |
Q24316909 | The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 |
Q35829284 | The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase |
Q39877610 | The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure |
Q34478554 | The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase |
Q28586574 | The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo |
Q28487547 | The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts |
Q44463888 | The role of yeast DNA 3'-phosphatase Tpp1 and rad1/Rad10 endonuclease in processing spontaneous and induced base lesions |
Q33689355 | Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells |
Q35099098 | Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair |
Q91666345 | Transcriptome changes in undifferentiated Caco-2 cells exposed to food-grade titanium dioxide (E171): contribution of the nano- and micro- sized particles |
Q40395945 | Untwisting of the DNA helix stimulates the endonuclease activity of Bacillus subtilis Nth at AP sites |
Q21558646 | Variant base excision repair proteins: contributors to genomic instability |
Q42683844 | Visualizing the Search for Radiation-damaged DNA Bases in Real Time |
Q39142123 | Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization |