DNA glycosylases search for and remove oxidized DNA bases

scientific article published on 07 October 2013

DNA glycosylases search for and remove oxidized DNA bases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EM.21820
P932PMC publication ID3997179
P698PubMed publication ID24123395
P5875ResearchGate publication ID257756339

P50authorSusan S WallaceQ41886664
P2860cites workRole of oxidative/nitrosative stress-mediated Bcl-2 regulation in apoptosis and malignant transformationQ23918829
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoinQ24294893
Characterization of a mammalian homolog of the Escherichia coli MutY mismatch repair proteinQ24309547
Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damageQ24311128
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease IIIQ24311942
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiaeQ24317398
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNAQ24318591
Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutantQ24322513
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNAQ24531459
Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediateQ24534729
Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA.Q24536790
The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activityQ24564283
Crystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8Q24630698
Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichla coliQ24632415
Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibilityQ24811220
Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNAQ24816127
The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damageQ27021912
Base excision repair and cancerQ27025537
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNAQ27638483
Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutMQ27639141
DNA lesion recognition by the bacterial repair enzyme MutMQ27642268
Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding modeQ27651223
Structural Characterization of a Viral NEIL1 Ortholog Unliganded and Bound to Abasic Site-containing DNAQ27656645
Entrapment and Structure of an Extrahelical Guanine Attempting to Enter the Active Site of a Bacterial DNA Glycosylase, MutMQ27658059
Encounter and extrusion of an intrahelical lesion by a DNA repair enzymeQ27658654
Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2.Q38334473
Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylaseQ38338981
Escherichia coli Fpg protein and UvrABC endonuclease repair DNA damage induced by methylene blue plus visible light in vivo and in vitroQ39941772
Reactions of oxyl radicals with DNA.Q40456587
Enzymatic recognition of DNA modifications induced by singlet oxygen and photosensitizersQ40524933
5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylasesQ27667498
Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanineQ27670719
Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNAQ27675877
Structural Characterization of Viral Ortholog of Human DNA Glycosylase NEIL1 Bound to Thymine Glycol or 5-Hydroxyuracil-containing DNAQ27676196
Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutMQ27676354
Strandwise translocation of a DNA glycosylase on undamaged DNAQ27676544
Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damageQ28114912
Oxidative damage to DNA in mammalian chromatinQ28188437
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIIIQ28201222
Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2Q28206447
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesionsQ28208731
A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologueQ28219332
Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesionsQ28239818
DNA glycosylase recognition and catalysisQ28257898
AP endonuclease-independent DNA base excision repair in human cellsQ28272662
Cloning and characterization of a mouse homologue (mNthl1) of Escherichia coli endonuclease IIIQ28282942
Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease IIIQ28304354
Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylaseQ28507243
Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like proteinQ28509553
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivoQ28586574
Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologueQ28610622
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylaseQ28610627
Surviving an Oxygen Atmosphere: DNA Damage and RepairQ28752302
Repair of oxidative damage to DNA: enzymology and biologyQ29618065
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteinsQ30576104
RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structuresQ33546272
Functional expression of hMYH, a human homolog of the Escherichia coli MutY proteinQ33636195
Base excision repair of DNA in mammalian cellsQ33957142
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomesQ34103846
Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxideQ34189100
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteinsQ34360665
Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence contextQ34362594
Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional roleQ34363320
Repair and genetic consequences of endogenous DNA base damage in mammalian cellsQ34371854
The one-dimensional diffusion coefficient of proteins absorbed on DNA. Hydrodynamic considerationsQ41076724
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brainsQ41849343
Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc fingerQ41864512
Expression patterns of Neil3 during embryonic brain development and neoplasiaQ41877342
Thermodynamics of the multi-stage DNA lesion recognition and repair by formamidopyrimidine-DNA glycosylase using pyrrolocytosine fluorescence--stopped-flow pre-steady-state kineticsQ42157248
Reversible chemical step and rate-limiting enzyme regeneration in the reaction catalyzed by formamidopyrimidine-DNA glycosylase.Q43260157
Characterization of the Escherichia coli X-ray endonuclease, endonuclease III.Q43860794
Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombeQ43862921
Expression and purification of NEIL3, a human DNA glycosylase homologQ44473499
Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysisQ44649058
DNA damage recognition and repair by the murine MutY homologueQ45144370
Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA.Q45185016
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymesQ46749944
Interaction of the human DNA glycosylase NEIL1 with proliferating cell nuclear antigen. The potential for replication-associated repair of oxidized bases in mammalian genomesQ46886711
Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization.Q50796195
Isolation and characterization of endonuclease VIII from Escherichia coli.Q54640652
Function of the zinc finger in Escherichia coli Fpg protein.Q54646766
Oxidative damage in DNA. Lack of mutagenicity by thymine glycol lesions.Q54748389
Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adductsQ56658839
Diffusion Constant of a Nonspecifically Bound Protein Undergoing Curvilinear Motion along DNA†Q60158913
Characterization ofEscherichia coliEndonuclease VIIIQ62061105
Formation of alpha-deoxyadenosine in polydeoxynucleotides exposed to ionizing radiation under anoxic conditionsQ68732550
High expression of DNA repair pathways is associated with metastasis in melanoma patientsQ81343404
Base excision repair.Q34374847
Free radical-induced damage to DNA: mechanisms and measurementQ34658029
Preferential repair of oxidized base damage in the transcribed genes of mammalian cellsQ34675663
Biological consequences of free radical-damaged DNA bases.Q34710048
Choreography of oxidative damage repair in mammalian genomesQ34710065
DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesionsQ35038055
Endonucleolytic incision of x-irradiated deoxyribonucleic acid by extracts of Escherichia coliQ35080156
The enigma of endonuclease VIII.Q35114231
Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNAQ35224383
Crosstalk of reactive oxygen species and NF-κB signalingQ35347850
Covalent trapping of protein-DNA complexesQ35550685
Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.Q35564216
Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damageQ35576447
Human MutY: gene structure, protein functions and interactions, and role in carcinogenesisQ35584123
Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutantsQ35624116
Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3'-phosphatase in maintenance of mitochondrial genomeQ35710132
Expression and purification of active mouse and human NEIL3 proteins.Q36044239
Bumps in the road: how replicative DNA polymerases see DNA damageQ36046468
Excision repair of thymine glycols, urea residues, and apurinic sites in Escherichia coliQ36209696
Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organismQ36231438
Rules of engagement for base excision repair in chromatinQ36309928
Mechanisms of formation, genotoxicity, and mutation of guanine oxidation productsQ36445449
Neil3, the final frontier for the DNA glycosylases that recognize oxidative damage.Q36853206
Physical and functional interaction between human oxidized base-specific DNA glycosylase NEIL1 and flap endonuclease 1Q36914462
Superior removal of hydantoin lesions relative to other oxidized bases by the human DNA glycosylase hNEIL1Q36952958
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.Q36972337
Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.Q37315825
Real-time studies of conformational dynamics of the repair enzyme E. coli formamidopyrimidine-DNA glycosylase and its DNA complexes during catalytic cycleQ37596621
Redox regulation of Wnt signalling via nucleoredoxinQ37699347
Redox-control of matrix metalloproteinase-1: a critical link between free radicals, matrix remodeling and degenerative diseaseQ37784064
Redox regulation of Nox proteinsQ37795167
The catalytic mechanism of Fpg protein. Evidence for a Schiff base intermediate and amino terminus localization of the catalytic siteQ38295362
Pre-steady-state kinetic study of substrate specificity of Escherichia coli formamidopyrimidine--DNA glycosylaseQ38305953
Structure of a DNA glycosylase searching for lesionsQ38315509
P433issue9
P304page(s)691-704
P577publication date2013-10-07
P1433published inEnvironmental and Molecular MutagenesisQ15724469
P1476titleDNA glycosylases search for and remove oxidized DNA bases
P478volume54

Reverse relations

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