Structurally Distinct Recognition Motifs in Lymphotoxin-β Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling

scientific article published on September 29, 2003

Structurally Distinct Recognition Motifs in Lymphotoxin-β Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M309381200
P953full work available at URLhttp://www.jbc.org/article/S0021925820755730/pdf
https://api.elsevier.com/content/article/PII:S0021925820755730?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0021925820755730?httpAccept=text/xml
https://syndication.highwire.org/content/doi/10.1074/jbc.M309381200
P3181OpenCitations bibliographic resource ID4865509
P698PubMed publication ID14517219

P2093author name stringJohn C. Reed
Chao-Zhou Ni
Chenglong Li
Edelmira Cabezas
Carl F. Ware
Kathryn R. Ely
Arnold C. Satterthwait
Marnie L. Havert
Paula S. Norris
Elizabeth M. Chiong
Bonnie R. Tran
P2860cites workThe lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cellsQ22254033
Downstream regulator TANK binds to the CD40 recognition site on TRAF3Q24297105
Distinct molecular mechanism for initiating TRAF6 signallingQ24302174
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40Q24306620
Involvement of CRAF1, a relative of TRAF, in CD40 signalingQ24306746
LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediatorQ24308657
A lymphotoxin-beta-specific receptorQ24312186
I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transductionQ24313173
Lymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaBQ24564927
Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming proteinQ24599252
Molecular basis for CD40 signaling mediated by TRAF3Q24656208
Crystallographic analysis of CD40 recognition and signaling by human TRAF2Q24675068
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
Structural basis for self-association and receptor recognition of human TRAF2Q27617947
The structural basis for the recognition of diverse receptor sequences by TRAF2Q27619945
Convergent solutions to binding at a protein-protein interfaceQ27621452
MOLMOL: a program for display and analysis of macromolecular structuresQ27860873
The peroxisomal membrane protein Pex13p shows a novel mode of SH3 interactionQ27938967
The TNF and TNF receptor superfamilies: integrating mammalian biologyQ28203717
Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-beta receptorQ28255713
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptorQ28282051
The CD40 antigen and its ligandQ28286277
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor familyQ28307399
Unraveling hot spots in binding interfaces: progress and challengesQ29614463
Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor linesQ34381306
Signaling by CD40 and its mimics in B cell activationQ34397107
Human TNF receptor-associated factor 5 (TRAF5): cDNA cloning, expression and assignment of the TRAF5 gene to chromosome 1q32.Q34428280
Structurally adaptive hot spots at a protein interaction interface on TRAF3.Q35007303
Death and survival: viral regulation of TNF signaling pathwaysQ35031970
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathwaysQ40696432
How B and T cells talk to each otherQ40714365
Immune regulation by CD40 and its ligand GP39.Q41039754
Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathwaysQ41728935
Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.Q44130049
Energetic determinants of internal motif recognition by PDZ domainsQ46062615
TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activationQ48064873
Side-chain flexibility in proteins upon ligand binding.Q52080522
Crystallization and preliminary X-ray analysis of the TRAF domain of TRAF3Q74506495
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
cell biologyQ7141
signal transductionQ828130
signal transducing adaptor proteinQ5964993
P304page(s)50523-9
P577publication date2003-09-29
2003-12-12
P1433published inJournal of Biological ChemistryQ867727
P1476titleStructurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling
Structurally Distinct Recognition Motifs in Lymphotoxin-β Receptor and CD40 for Tumor Necrosis Factor Receptor-associated Factor (TRAF)-mediated Signaling
P478volume278

Reverse relations

cites work (P2860)
Q37026428A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.
Q33883378Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor
Q35925874Assembly of post-receptor signaling complexes for the tumor necrosis factor receptor superfamily
Q28474495Beauty is in the eye of the beholder: proteins can recognize binding sites of homologous proteins in more than one way
Q38919438Comparison of the peptide binding preferences of three closely related TRAF paralogs: TRAF2, TRAF3, and TRAF5
Q35946248Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes.
Q27680632Dimerization of LT R by LT 1 2 is necessary and sufficient for signal transduction
Q24294565Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases
Q37678950Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma.
Q37314736Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
Q37948116How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members?
Q90575916Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease
Q38960255Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor
Q33725721Inference of surface membrane factors of HIV-1 infection through functional interaction networks
Q45436282LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3.
Q36918115Molecular basis of NF-κB signaling
Q52337490Negative Regulation of Interferon-β Production by Alternative Splicing of Tumor Necrosis Factor Receptor-Associated Factor 3 in Ducks.
Q33849388Oncogenic activation of NF-kappaB.
Q35634096Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
Q27023925Roles of TRAF3 in T cells: many surprises
Q39814540Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1
Q27675124Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Q27649432Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome
Q63915433T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword
Q36572388TRAF family member-associated NF-kappa B activator (TANK) expression increases in injured sensory neurons and is transcriptionally regulated by Sox11.
Q33707599TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling
Q50792035TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation.
Q38840587TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry.
Q37132817TRAF4, at the Crossroad between Morphogenesis and Cancer
Q37036159Targeting lymphocyte activation through the lymphotoxin and LIGHT pathways
Q24314976The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation