Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways

scientific article published on April 2000

Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.275.15.11121
P698PubMed publication ID10753918

P2093author name stringWare CF
Lama J
Benedict CA
Cheung TC
Force WR
Glass AA
P2860cites workTargeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses.Q52522634
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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorQ24318280
Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1Q24323286
Lymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaBQ24564927
Crystallographic analysis of CD40 recognition and signaling by human TRAF2Q24675068
Structural basis for self-association and receptor recognition of human TRAF2Q27617947
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Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient miceQ28140546
Expression of the lymphotoxin beta receptor on follicular stromal cells in human lymphoid tissuesQ28141400
The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cellsQ28141786
The lymphotoxin-alpha (LTalpha) subunit is essential for the assembly, but not for the receptor specificity, of the membrane-anchored LTalpha1beta2 heterotrimeric ligandQ28244596
Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-beta receptorQ28255713
TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptorQ28282051
Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor familyQ28295196
Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activationQ28584897
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and deathQ28609905
Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa BQ28615823
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient miceQ29618716
Suppression of TNF-alpha-induced apoptosis by NF-kappaBQ29618717
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Tumor necrosis factor receptor and Fas signaling mechanisms.Q33652491
Development and maturation of secondary lymphoid tissues.Q33652498
Interaction of tumor necrosis factor receptor-associated factor signaling proteins with the latent membrane protein 1 PXQXT motif is essential for induction of epidermal growth factor receptor expressionQ33786551
Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor linesQ34381306
Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph nodeQ36157845
Requirement for membrane lymphotoxin in natural killer cell development.Q37206961
CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFsQ40955336
Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell typesQ41159609
Complementation of lymphotoxin alpha knockout mice with tumor necrosis factor-expressing transgenes rectifies defective splenic structure and functionQ41845395
Preparation and characterization of soluble recombinant heterotrimeric complexes of human lymphotoxins alpha and beta.Q42064466
A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development: genetic evidence of synergism with lymphotoxin betaQ42736587
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factorQ42943618
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissuesQ47713235
Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory lymphokines.Q50922303
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)11121-11129
P577publication date2000-04-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleDiscrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways
P478volume275

Reverse relations

cites work (P2860)
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