Structural basis for bifunctional peptide recognition at human δ-opioid receptor

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Structural basis for bifunctional peptide recognition at human δ-opioid receptor is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1043208053
P356DOI10.1038/NSMB.2965
P8608Fatcat IDrelease_rjynnkdwabgwzeyftuaf3xpcku
P3181OpenCitations bibliographic resource ID3966479
P932PMC publication ID4351130
P698PubMed publication ID25686086
P5875ResearchGate publication ID272422033

P50authorRaymond C. StevensQ7298638
Thomas A WhiteQ56073471
Haitao ZhangQ57242845
Raimund FrommeQ63346869
Nadia A. ZatsepinQ80123959
Jesse CoeQ88391463
Gye Won HanQ88435974
Bryan L. RothQ89688393
Petra FrommeQ89794023
Dominik OberthuerQ90428016
Shibom BasuQ91099462
Andrii IshchenkoQ91767554
Markus MetzQ96142142
Cornelius GatiQ96577247
Chelsie E. ConradQ103836877
Gustavo FenaltiQ114336928
Dingjie WangQ114401575
Patrick M GiguereQ117222586
Wei LiuQ124538811
Vsevolod KatritchQ28317231
Vadim CherezovQ28320126
Marc MesserschmidtQ28321841
Sébastien BoutetQ28321847
Uwe WeierstallQ28321855
Anton BartyQ28359711
Oleksandr YefanovQ43422867
Henry N. ChapmanQ46344491
Daniel JamesQ55777508
P2093author name stringGarth J Williams
John C H Spence
Peter W Schiller
Chun Hong Yoon
Dirk Tourwé
Karel Guillemyn
Steven Ballet
Cecilia Betti
P2860cites workStructure of the human κ-opioid receptor in complex with JDTicQ24308048
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
The genetic design of signaling cascades to record receptor activationQ24657333
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallographyQ27639826
Structural Basis for Allosteric Regulation of GPCRs by Sodium IonsQ27670746
Structure of the agonist-bound neurotensin receptorQ27674395
Crystal structure of the µ-opioid receptor bound to a morphinan antagonistQ27678133
Structure of the δ-opioid receptor bound to naltrindoleQ27679153
Serial Femtosecond Crystallography of G Protein-Coupled ReceptorsQ27680992
Molecular control of δ-opioid receptor signallingQ27681274
Influence of sample pH on the conformational backbone dynamics of a pseudotripeptide (H-Tyr-Tic psi [CH2-NH]Phe-OH) incorporating a reduced peptide bond: an NMR investigationQ70884269
CrystFEL: a software suite for snapshot serial crystallographyQ106111061
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallographyQ27681713
Phasercrystallographic softwareQ27860930
Refinement of macromolecular structures by the maximum-likelihood methodQ27861011
Features and development of CootQ27861079
Crystallizing membrane proteins using lipidic mesophasesQ29616431
Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.Q30365684
Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction dataQ30829393
Subtleties of structure-agonist versus antagonist relationships of opioid peptides and peptidomimeticsQ33540001
Bi- or multifunctional opioid peptide drugsQ33767037
Opioids and their receptors: Are we there yet?Q34437456
Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)Q35120622
Dmt and opioid peptides: a potent allianceQ35136105
Synthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities.Q37186178
Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonistsQ37342344
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffoldQ37342753
TIPP[psi]: a highly potent and stable pseudopeptide delta opioid receptor antagonist with extraordinary delta selectivityQ42286468
Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in miceQ44333988
The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in ratsQ44352759
Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bondQ44387092
P433issue3
P921main subjectopioidQ427523
structural biologyQ908902
P304page(s)265-268
P577publication date2015-03-01
P1433published inNature Structural & Molecular BiologyQ1071739
P1476titleStructural basis for bifunctional peptide recognition at human δ-opioid receptor
P478volume22

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cites work (P2860)
Q61809633: a reference-based auto-indexing algorithm for sparse serial crystallography data
Q38653533A Bright Future for Serial Femtosecond Crystallography with XFELs.
Q37574675A Cyclic Tetrapeptide ("Cyclodal") and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists
Q35637848A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior.
Q47348737A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?
Q35692417A novel inert crystal delivery medium for serial femtosecond crystallography.
Q96132105Advances in therapeutic peptides targeting G protein-coupled receptors
Q36084217Atomic resolution structure determination by the cryo-EM method MicroED.
Q38743944Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation
Q44341109Conformational Heterogeneity of Intracellular Loop 3 of the μ-opioid G-protein Coupled Receptor
Q38749484Crystallization of Membrane Proteins: An Overview
Q91669090DatView: a graphical user interface for visualizing and querying large data sets in serial femtosecond crystallography
Q43075987Designing Safer Analgesics via μ-Opioid Receptor Pathways
Q91742965Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
Q47567861Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo
Q36635468Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities.
Q26752403G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs
Q55278334G protein-coupled receptors: the evolution of structural insight.
Q38812016Hitchhiking on the heptahelical highway: structure and function of 7TM receptor complexes.
Q51037057Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds.
Q30653915In meso in situ serial X-ray crystallography of soluble and membrane proteins
Q27316812In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures
Q52665081In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease.
Q52315660Insights from molecular dynamics simulations to exploit new trends for the development of improved opioid drugs
Q39165104Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures.
Q101476174Isoprenoid-chained lipid EROCOC17+4: a new matrix for membrane protein crystallization and a crystal delivery medium in serial femtosecond crystallography
Q27334433Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography
Q26784007Membrane protein structural biology using X-ray free electron lasers
Q37062556Molecular Pharmacology of δ-Opioid Receptors
Q98895948Molecular-Level Understanding of the Somatostatin Receptor 1 (SSTR1)-Ligand Binding: A Structural Biology Study Based on Computational Methods
Q50905291Nanoscale clustering of the neurotrophin receptor TrkB revealed by super-resolution STED microscopy
Q38718788New Technologies for Elucidating Opioid Receptor Function
Q39332114New approaches towards the understanding of integral membrane proteins: A structural perspective on G protein-coupled receptors
Q93222349Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency
Q64068526On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity
Q44345123Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.
Q30393367Possibilities for serial femtosecond crystallography sample delivery at future light sources
Q36147702Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
Q44343199Propagation of the Allosteric Modulation Induced by Sodium in the δ-Opioid Receptor
Q37108546Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors
Q64949661Serial Femtosecond Crystallography of G Protein-Coupled Receptors.
Q36110683Serial Femtosecond Crystallography of Membrane Proteins
Q36390354Serial Synchrotron X-Ray Crystallography (SSX).
Q35901032Serial femtosecond X-ray diffraction of enveloped virus microcrystals
Q36091742Serial femtosecond crystallography datasets from G protein-coupled receptors
Q30367012Serial femtosecond crystallography opens new avenues for Structural Biology.
Q30387614Serial femtosecond crystallography: A revolution in structural biology.
Q27318592Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides
Q51761770Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM.
Q47558272Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Q56674183Structure of the µ-opioid receptor–Gi protein complex
Q26331003Structure-based discovery of opioid analgesics with reduced side effects
Q36230191Targeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development.
Q88737142The fine art of integral membrane protein crystallisation
Q35901023Time-resolved structural studies with serial crystallography: A new light on retinal proteins
Q92768615Understanding Peptide Binding in Class A G Protein-Coupled Receptors
Q28834461XFELs open a new era in structural chemical biology
Q41840052[Dmt(1)]DALDA analogues modified with tyrosine analogues at position 1.

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