| scholarly article | Q13442814 |
| P50 | author | Lindsay L Jones | Q55175518 |
| P2093 | author name string | K Christopher Garcia | |
| Leremy A Colf | |||
| David M Kranz | |||
| Jennifer D Stone | |||
| P2860 | cites work | Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination | Q26778405 |
| Processing of X-ray diffraction data collected in oscillation mode | Q26778468 | ||
| Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor | Q27618536 | ||
| A functional hot spot for antigen recognition in a superagonist TCR/MHC complex | Q27622127 | ||
| A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex | Q27638477 | ||
| A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity | Q27640322 | ||
| CDR3 loop flexibility contributes to the degeneracy of TCR recognition | Q27640417 | ||
| How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? | Q27644089 | ||
| How a single T cell receptor recognizes both self and foreign MHC | Q27644381 | ||
| Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon' | Q27647150 | ||
| The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain | Q27649862 | ||
| Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules | Q27649963 | ||
| Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen | Q27748865 | ||
| Coot: model-building tools for molecular graphics | Q27860505 | ||
| T cell killing does not require the formation of a stable mature immunological synapse. | Q46039675 | ||
| Ligand recognition by alpha beta T cell receptors | Q46222293 | ||
| Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants | Q46730433 | ||
| Conformational flexibility and kinetic complexity in antibody-antigen interactions | Q47800178 | ||
| Directed evolution of a stable scaffold for T-cell receptor engineering. | Q54045046 | ||
| The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition | Q56917578 | ||
| Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation | Q73022474 | ||
| Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition | Q74545050 | ||
| A very high level of crossreactivity is an essential feature of the T-cell receptor | Q77324273 | ||
| TCR binding to peptide-MHC stabilizes a flexible recognition interface | Q77328526 | ||
| Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand | Q81319303 | ||
| Stereochemical quality of protein structure coordinates | Q27860874 | ||
| Pushing the boundaries of molecular replacement with maximum likelihood | Q27860922 | ||
| How TCRs bind MHCs, peptides, and coreceptors | Q29619572 | ||
| T-cell antigen receptor genes and T-cell recognition | Q29619721 | ||
| In vitro evolution of a T cell receptor with high affinity for peptide/MHC. | Q30861962 | ||
| TCRs with high affinity for foreign pMHC show self-reactivity | Q30873107 | ||
| Specificity and degeneracy of T cells | Q33199993 | ||
| Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function | Q33229925 | ||
| Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld. | Q33248619 | ||
| High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines. | Q33303162 | ||
| T-cell allorecognition: a case of mistaken identity or déjà vu? | Q33345391 | ||
| Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization | Q33731073 | ||
| Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule | Q33947114 | ||
| Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor | Q34099738 | ||
| Positive and negative selection of T cells | Q34157557 | ||
| The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy. | Q34578981 | ||
| Kinetic and affinity limits on antibodies produced during immune responses | Q34598643 | ||
| Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction | Q35025046 | ||
| Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning | Q35651348 | ||
| T cell receptor crossreactivity as a general property of T cell recognition | Q35704654 | ||
| High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins | Q35918289 | ||
| Breaking the affinity ceiling for antibodies and T cell receptors | Q36113815 | ||
| How the T cell receptor sees antigen--a structural view | Q36226908 | ||
| Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis | Q36237629 | ||
| Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera | Q36247967 | ||
| Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes | Q36368381 | ||
| CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. | Q36369627 | ||
| Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers | Q36375751 | ||
| T cell cross-reactivity and conformational changes during TCR engagement | Q36399643 | ||
| A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone | Q36699072 | ||
| Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone | Q36813012 | ||
| HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides | Q36954248 | ||
| Protein dynamics and the immunological evolution of molecular recognition. | Q37094819 | ||
| Evolutionarily conserved amino acids that control TCR-MHC interaction | Q37096091 | ||
| Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide | Q40220156 | ||
| CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse | Q44973640 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6255-64 | |
| P577 | publication date | 2008-11-01 | |
| P1433 | published in | Journal of Immunology | Q3521441 |
| P1476 | title | Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation | |
| P478 | volume | 181 |
| Q42290491 | A unifying mathematical framework for experimental TCR-pMHC kinetic constants |
| Q27652700 | Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors † ‡ |
| Q37432048 | Different strategies adopted by K(b) and L(d) to generate T cell specificity directed against their respective bound peptides |
| Q27675164 | Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism |
| Q34436547 | Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function |
| Q30837264 | DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles |
| Q47782025 | Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes |
| Q33375887 | Engineering higher affinity T cell receptors using a T cell display system |
| Q27331858 | Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex |
| Q37518497 | Functional implications of T cell receptor diversity |
| Q47438128 | Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro |
| Q37657355 | Grading the commercial optical biosensor literature-Class of 2008: 'The Mighty Binders'. |
| Q30844013 | Hypergravity exposure during gestation modifies the TCRβ repertoire of newborn mice |
| Q35612835 | Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs |
| Q37172418 | Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions |
| Q34983206 | Opposite effects of endogenous peptide-MHC class I on T cell activity in the presence and absence of CD8. |
| Q34953926 | Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes |
| Q90093156 | Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8+ T Cell Receptors |
| Q35694340 | Quantitative Analysis of the Association Angle between T-cell Receptor Vα/Vβ Domains Reveals Important Features for Epitope Recognition |
| Q28270580 | Reconciling views on T cell receptor germline bias for MHC |
| Q37107843 | Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies |
| Q36386316 | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. |
| Q47260351 | Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity |
| Q27675661 | T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex |
| Q64973005 | T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability. |
| Q37363263 | T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity |
| Q28081699 | TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity |
| Q27670624 | The Peptide-Receptive Transition State of MHC Class I Molecules: Insight from Structure and Molecular Dynamics |
| Q33351448 | The effect of mutations on the alloreactive T cell receptor/peptide-MHC interface structure: a molecular dynamics study |
| Q33737674 | The impact of TCR-binding properties and antigen presentation format on T cell responsiveness |
| Q28306893 | The molecular basis of TCR germline bias for MHC is surprisingly simple |
| Q44447688 | Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics |
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