| Q46052878 | A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination. |
| Q56112100 | A Response Calculus for Immobilized T Cell Receptor Ligands |
| Q40063793 | A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions. |
| Q35850974 | A comprehensive calorimetric investigation of an entropically driven T cell receptor-peptide/major histocompatibility complex interaction |
| Q36737191 | A coupled diffusion-kinetics model for analysis of contact-area FRAP experiment |
| Q74297571 | A diverse set of oligomeric class II MHC-peptide complexes for probing T-cell receptor interactions |
| Q38360461 | A dominant negative mutant beta 2-microglobulin blocks the extracellular folding of a major histocompatibility complex class I heavy chain |
| Q37193981 | A hypothesis accounting for the paradoxical expression of the D gene segment in the BCR and the TCR. |
| Q41649927 | A kinetic basis for T cell receptor repertoire selection during an immune response |
| Q36369989 | A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex |
| Q52930208 | A kinetic window constricts the T cell receptor repertoire in the thymus. |
| Q30497170 | A large T cell invagination with CD2 enrichment resets receptor engagement in the immunological synapse |
| Q35101815 | A model T-cell receptor system for studying memory T-cell development |
| Q34784647 | A new trigger for T cells |
| Q33738896 | A quantitative real time PCR method to analyze T cell receptor Vbeta subgroup expansion by staphylococcal superantigens |
| Q35645928 | A robust method for production of MHC tetramers with small molecule fluorophores |
| Q73435403 | A simplified procedure for the preparation of MHC/peptide tetramers: chemical biotinylation of an unpaired cysteine engineered at the C-terminus of MHC-I |
| Q37355429 | A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells |
| Q47967435 | A single residue exchange between two HLA-B27 alleles triggers increased peptide flexibility |
| Q31123020 | A yeast display system for engineering functional peptide-MHC complexes |
| Q51984292 | Activated mouse T cells downregulate, process and present their surface TCR to cognate anti-idiotypic CD4+ T cells. |
| Q37072087 | Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo |
| Q40005191 | Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX. |
| Q58698089 | Adhesive Interactions Delineate the Topography of the Immune Synapse |
| Q90479566 | Adoptive Cell Therapy Targeting Neoantigens: A Frontier for Cancer Research |
| Q27675301 | Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses |
| Q46681223 | Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity |
| Q44851304 | Alpha-Galactosylceramide/CD1d-Antibody Fusion Proteins Redirect Invariant Natural Killer T Cell Immunity to Solid Tumors and Promote Prolonged Therapeutic Responses |
| Q36368633 | Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2. |
| Q42187437 | Amino-terminal extended peptide single-chain trimers are potent synthetic agonists for memory human CD8+ T cells |
| Q64965547 | An Antibody Fab Fragment-based Chimeric Antigen Receptor Could Efficiently Eliminate Human Thyroid Cancer Cells. |
| Q35936478 | An integrated view of suppressor T cell subsets in immunoregulation |
| Q58046629 | Analysis of pattern formation and phase separation in the immunological synapse |
| Q33828012 | Analysis of the CDR3 length repertoire and the diversity of T cell receptor α and β chains in swine CD4+ and CD8+ T lymphocytes |
| Q37032182 | Analysis of the complementarity determining regions β-chain genomic rearrangement using high-throughput sequencing in periphery cytotoxic T lymphocytes of patients with chronic hepatitis B |
| Q52534683 | Antagonism of cytotoxic T-lymphocyte activation by soluble CD8. |
| Q34263452 | Antigen decoding by T lymphocytes: from synapses to fate determination |
| Q44555210 | Antigen presentation on MHC molecules as a diversity filter that enhances immune efficacy |
| Q36732651 | Antigen recognition by gammadelta T cells |
| Q34104912 | Antigen-recognition properties of murine gamma delta T cells |
| Q24800475 | Antigen-specific T cells: analyses of the needles in the haystack |
| Q73166239 | Antigen-specific elimination of T cells induced by oligomerized hemagglutinin (HA) 306-318 |
| Q46798411 | Artificial antigen-presenting cells as a tool to exploit the immune 'synapse'. |
| Q28610392 | Asymmetric ligand recognition by the activating natural killer cell receptor NKG2D, a symmetric homodimer |
| Q33698019 | Attenuated T cell responses to a high-potency ligand in vivo |
| Q35215151 | B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection |
| Q37352024 | Beyond thermodynamics: drug binding kinetics could influence epidermal growth factor signaling |
| Q36759301 | Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors |
| Q33720544 | Binding energetics of T-cell receptors: correlation with immunological consequences |
| Q34516547 | Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes |
| Q34077153 | Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis. |
| Q36748257 | CD4(+) and CD8(+) TCRβ repertoires possess different potentials to generate extraordinarily high-avidity T cells |
| Q57275526 | CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes |
| Q35660783 | CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections |
| Q35729030 | CD8 T cell responses to viral infections in sequence |
| Q39655504 | CD8 controls T cell cross-reactivity |
| Q40404578 | CD8 kinetically promotes ligand binding to the T-cell antigen receptor. |
| Q36369627 | CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation. |
| Q38819803 | CalQuo: automated, simultaneous single-cell and population-level quantification of global intracellular Ca2+ responses |
| Q34174888 | Calculations show substantial serial engagement of T cell receptors |
| Q39930758 | Can oligomeric T-cell receptor be used as a tool to detect viral peptide epitopes on infected cells? |
| Q37209197 | Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors |
| Q36333439 | Cells, cytokines and cellular immunity in the pathogenesis of fibroproliferative vasculopathies |
| Q36100167 | Cellular immunotherapy: antigen recognition is just the beginning. |
| Q39534409 | Characterization and functional analyses of a novel chicken CD8α variant X1 (CD8α1). |
| Q52005454 | Characterization of CC‐chemokine receptor 7 expression on murine T cells in lymphoid tissues |
| Q44372354 | Characterization of T cell hybridomas raised against a glycopeptide containing the tumor-associated T antigen, (betaGal (1-3) alphaGalNAc-O/Ser). |
| Q57840014 | Characterizing the functionality of recombinant T-cell receptors in vitro: a pMHC tetramer based approach |
| Q96817033 | Chd4 choreographs self-antigen expression for central immune tolerance |
| Q42410761 | Cholesterol and sphingomyelin drive ligand-independent T-cell antigen receptor nanoclustering |
| Q37077802 | Class II major histocompatibility complex tetramer staining: progress, problems, and prospects |
| Q33229925 | Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function |
| Q73486149 | Clonal expansion of T cells infiltrating in the airways of non-atopic asthmatics |
| Q39025670 | Clonotype-specific avidity influences the dynamics and hierarchy of virus-specific regulatory and effector CD4(+) T-cell responses. |
| Q35005884 | Clustering of MHC-peptide complexes prior to their engagement in the immunological synapse: lipid raft and tetraspan microdomains |
| Q24291172 | Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA |
| Q48381032 | Complexity of the T cell receptor Cbeta isotypes in the Mexican axolotl: structure and diversity of the VDJCbeta3 and VDJCbeta4 chains. |
| Q37272711 | Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes |
| Q36054301 | Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes |
| Q37313736 | Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models. |
| Q44735993 | Contribution of a single hydrogen bond between betaHis81 of MHC class II I-E(k) and the bound peptide to the pH-dependent thermal stability |
| Q91028125 | Control of Antibody Impurities Induced by Riboflavin in Culture Media During Production |
| Q48374679 | Coronary arteries with chronic rejection contain oligoclonal T cells: persistence of clonally expanded T cell receptor transcripts from the early posttransplantation period through chronic rejection |
| Q34895271 | Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation. |
| Q24290869 | Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells |
| Q36375751 | Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers |
| Q27666700 | Crystal structure of a T-cell receptor specific for the human MHC class I homolog MICA |
| Q27639768 | Crystal structure of an MHC class I presented glycopeptide that generates carbohydrate-specific CTL |
| Q27618584 | Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand |
| Q37789411 | Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes |
| Q56888747 | Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans |
| Q33754742 | Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response |
| Q34520749 | Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength |
| Q28741917 | Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis |
| Q53631492 | Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition. |
| Q24800142 | Detection and characterization of cellular immune responses using peptide-MHC microarrays |
| Q36770660 | Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer |
| Q34478717 | Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms. |
| Q36342860 | Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. |
| Q35223576 | Dextramer reagents are effective tools for quantifying CMV antigen-specific T cells from peripheral blood samples |
| Q34297618 | Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies |
| Q37857379 | Dimeric MHC-peptides inserted into an immunoglobulin scaffold as new immunotherapeutic agents |
| Q33239176 | Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity |
| Q35025046 | Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction |
| Q40953960 | Distant interactions between dimorphisms in HLA-DR4 radically affect recognition of defined peptides by a specific T cell clone |
| Q27652612 | Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation |
| Q30504688 | Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses |
| Q41753346 | Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities |
| Q35798907 | Diversity index of mucosal resident T lymphocyte repertoire predicts clinical prognosis in gastric cancer |
| Q34436547 | Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function |
| Q36375607 | Dynamic interactions of macrophages with T cells during antigen presentation. |
| Q24291267 | Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transduction |
| Q35550692 | Dynamics of Cell Surface Molecules During T Cell Recognition |
| Q39758413 | Effect of multiple genetic polymorphisms on antigen presentation and susceptibility to Mycobacterium tuberculosis infection |
| Q26995251 | Effective T helper cell responses against retroviruses: are all clonotypes equal? |
| Q58043781 | Effects of somatic mutations on CDR loop flexibility during affinity maturation |
| Q44255903 | Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex |
| Q51594643 | Engineered T-cell receptor tetramers bind MHC-peptide complexes with high affinity. |
| Q33375887 | Engineering higher affinity T cell receptors using a T cell display system |
| Q34624124 | Engineering improved T cell receptors using an alanine-scan guided T cell display selection system |
| Q45867388 | Engineering mouse T lymphocytes specific to type II collagen by transduction with a chimeric receptor consisting of a single chain Fv and TCR zeta |
| Q73168752 | Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex |
| Q41306886 | Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region |
| Q35076549 | Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection |
| Q54574854 | Estimating diversity, the easy way. |
| Q40440555 | Evidence for MR1 antigen presentation to mucosal-associated invariant T cells |
| Q27642839 | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation |
| Q36368219 | Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs |
| Q44178988 | Evolution of catalytic antibody repertoire in autoimmune mice |
| Q47779893 | Evolutionarily conserved pattern of gene segment usage within the mammalian TCRbeta locus |
| Q38070787 | Evolving immune circuits are generated by flexible, motile, and sequential immunological synapses. |
| Q33770508 | Expanding Role of T Cells in Human Autoimmune Diseases of the Central Nervous System |
| Q30697884 | Exploring immunological specificity using synthetic peptide combinatorial libraries. |
| Q56888758 | Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells |
| Q51994109 | Feedback control of T-cell receptor activation. |
| Q36119302 | Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells. |
| Q27619289 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical |
| Q57363708 | From TCR Engagement to T Cell Activation |
| Q33840553 | From synapses to immunological memory: the role of sustained T cell stimulation |
| Q37406665 | From tango to quadrilla: current views of the immunological synapse. |
| Q24643913 | Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor |
| Q73667893 | Gamma-chain T-cell receptor transcripts are clonally expanded in the coronary arteries of cardiac allografts from patients with chronic rejection |
| Q34815646 | Generation and use of alternative multimers of peptide/MHC complexes |
| Q33185580 | Genetic engineering of T cell specificity for immunotherapy of cancer |
| Q24642718 | Genetic engineering of T cells for adoptive immunotherapy |
| Q37258523 | Glimpse of natural selection of long-lived T-cell clones in healthy life |
| Q34510727 | HLA class II tetramers: tools for direct analysis of antigen-specific CD4+ T cells |
| Q38268679 | HLA-E: a novel player for histocompatibility |
| Q34772077 | Haplotype exclusion and receptor editing: irreconcilable differences? |
| Q78524553 | Hierarchical signaling thresholds determine the fates of naíve T cells: partial priming leads nai;ve T cells to unresponsiveness |
| Q48667470 | High throughput analysis of TCR-beta rearrangement and gene expression in single T cells |
| Q55223802 | High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation. |
| Q33814783 | High-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics. |
| Q33303162 | High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines. |
| Q36045188 | How T cells 'see' antigen |
| Q30252510 | How and why do T cells and their derived cytokines affect the injured and healthy brain? |
| Q34553067 | How and why does the immunological synapse form? Physical chemistry meets cell biology |
| Q33795023 | Human cytomegalovirus elicits fetal gammadelta T cell responses in utero |
| Q34626991 | Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors. |
| Q36369186 | Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors |
| Q34353222 | Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease |
| Q26774669 | Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens |
| Q37285355 | Immune Repertoire Diversity Correlated with Mortality in Avian Influenza A (H7N9) Virus Infected Patients. |
| Q33899097 | Immunology and immunotherapy of human cancer: present concepts and clinical developments |
| Q81703535 | Immunotherapy and chemotherapy--a practical partnership |
| Q30861962 | In vitro evolution of a T cell receptor with high affinity for peptide/MHC. |
| Q99418879 | In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography |
| Q73035390 | Incompatible differences: view of an allogeneic pMHC-TCR complex |
| Q34013678 | Induction of T cell alertness by bacterial colonization of intestinal epithelium |
| Q35543380 | Influence of the route of infection on development of T-cell receptor beta-chain repertoires of reovirus-specific cytotoxic T lymphocytes |
| Q38188084 | Influenza reverse genetics: dissecting immunity and pathogenesis |
| Q37026523 | Inhibition of T cell receptor signaling by cholesterol sulfate, a naturally occurring derivative of membrane cholesterol |
| Q43968748 | Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse |
| Q46842083 | Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected] |
| Q36515364 | Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network |
| Q35927615 | Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters |
| Q90040247 | Insights into Thymus Development and Viral Thymic Infections |
| Q36740232 | Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface |
| Q73256383 | Interaction of the NK cell inhibitory receptor Ly49A with H-2Dd: identification of a site distinct from the TCR site |
| Q40220156 | Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide |
| Q28512242 | Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement |
| Q37620444 | Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. |
| Q47559673 | Irreversible thermodynamics of curved lipid membranes |
| Q52922603 | Junctional biases in the naive TCR repertoire control the CTL response to an immunodominant determinant of HSV-1. |
| Q38320280 | Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties. |
| Q36082149 | Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor |
| Q36237629 | Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis |
| Q37990731 | Life on a microarray: assessing live cell functions in a microarray format. |
| Q64071246 | Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling |
| Q37302234 | Lipid rafts and T-lymphocyte function: implications for autoimmunity |
| Q36447769 | Lipid rafts in T cell receptor signalling |
| Q60044246 | Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer |
| Q64057809 | Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer |
| Q39414393 | Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity |
| Q27674375 | Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN |
| Q81397327 | Low-dose antigen-experienced CD4+ T cells display reduced clonal expansion but facilitate an effective memory pool in response to secondary exposure |
| Q90013903 | MATE-Seq: microfluidic antigen-TCR engagement sequencing |
| Q41955439 | MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs. |
| Q37464963 | MHC restriction and allogeneic immune responses. |
| Q36368696 | Macrophage-tropic HIV induces and exploits dendritic cell chemotaxis |
| Q33838467 | Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE. |
| Q39041826 | Mechanical Communication at the Immunological Synapse |
| Q27016079 | Mechanical regulation of T-cell functions |
| Q37953322 | Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes |
| Q37673276 | Mechanisms of cellular communication through intercellular protein transfer |
| Q41118609 | Meeting report: Signal transduction meets systems biology |
| Q28235543 | Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules |
| Q36940065 | Methods for quantifying T cell receptor binding affinities and thermodynamics |
| Q50042689 | Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes. |
| Q33987727 | Microbial superantigens: from structure to function |
| Q38038563 | Microfabricated platforms to modulate and monitor T cell synapse assembly |
| Q36904137 | Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues |
| Q27639095 | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line |
| Q36891310 | Mobilizing the low-avidity T cell repertoire to kill tumors |
| Q24814731 | Modeling T cell antigen discrimination based on feedback control of digital ERK responses |
| Q34560511 | Modulation of CD4 T cell function by soluble MHC II-peptide chimeras |
| Q40061831 | Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity |
| Q38093572 | Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse. |
| Q55951804 | Molecular Competition for NKG2D |
| Q34754743 | Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands |
| Q34574696 | Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions |
| Q38117139 | Molecular insights for optimizing T cell receptor specificity against cancer |
| Q33815380 | Molecular interactions between extracellular components of the T-cell receptor signaling complex |
| Q33927920 | Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor |
| Q35622988 | Molecular mechanisms of host-pathogen interaction: entry and survival of mycobacteria in macrophages. |
| Q35096668 | Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. |
| Q36977064 | Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology |
| Q34282353 | Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling. |
| Q57255889 | Monomeric TCRs drive T cell antigen recognition |
| Q34770540 | Mutant RBL mast cells defective in Fc epsilon RI signaling and lipid raft biosynthesis are reconstituted by activated Rho-family GTPases |
| Q35925878 | NKG2D and Related Immunoreceptors |
| Q33470246 | NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation |
| Q40052007 | Natural Killer (NK) Cell Education Differentially Influences HIV Antibody-Dependent NK Cell Activation and Antibody-Dependent Cellular Cytotoxicity |
| Q40231068 | Natural killer cell (NK) subsets and NK-like T-cell populations in acute myeloid leukemias and myelodysplastic syndromes |
| Q34913212 | Naturally occurring CD4+ T-cell epitope variants act as altered peptide ligands leading to impaired helper T-cell responses in hepatitis C virus infection |
| Q34609924 | New concepts in the immunopathogenesis of multiple sclerosis |
| Q43186964 | Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse |
| Q38626628 | Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells |
| Q35046576 | Not just any T cell receptor will do. |
| Q42121659 | Novel Cellular Microarray Assay for Profiling T-Cell Peptide Antigen Specificities |
| Q36711567 | On a key postulate of T-cell receptor restrictive function: the V-gene loci act as a single pool encoding recognition of the polymorphic alleles of the species major histocompatibility complex |
| Q33541431 | On costimulatory signals and T cell tolerance: relevance for transplantation immunity. |
| Q35557688 | One lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptors |
| Q41709069 | Ontogeny of synonymous T cell populations with specificity for a self MHC epitope mimicked by a bacterial homologoue: an antigen-specific T cell analysis in a non-transgenic system |
| Q64071238 | Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor |
| Q34320305 | Organization of the resting TCR in nanoscale oligomers |
| Q104576046 | Origins and diversity of macrophages in health and disease |
| Q28587297 | POLKADOTS are foci of functional interactions in T-Cell receptor-mediated signaling to NF-kappaB. |
| Q37464168 | Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions. |
| Q51040397 | Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions. |
| Q33849372 | Perspectives for computer modeling in the study of T cell activation |
| Q37256881 | Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire |
| Q36401714 | Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor |
| Q39418908 | Potent T cell agonism mediated by a very rapid TCR/pMHC interaction |
| Q35896206 | Potential of human gammadelta T lymphocytes for immunotherapy of cancer |
| Q33530332 | Production of a soluble disulfide bond-linked TCR in the cytoplasm of Escherichia coli trxB gor mutants. |
| Q38356490 | Production of a soluble gammadelta T-cell receptor to identify ligands for the murine intestinal intraepithelial gammadelta T cell population |
| Q42153770 | Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding |
| Q54524412 | Production, characterization, and immunogenicity of a soluble rat single chain T cell receptor specific for an encephalitogenic peptide. |
| Q37359997 | Protein acylation and localization in T cell signaling (Review). |
| Q37170972 | Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response |
| Q34462479 | Protein therapeutics: promises and challenges for the 21st century |
| Q50237059 | Quantification of a Selective Expansion of T Cell Receptor Vβ by Superantigen Using Real-Time PCR. |
| Q34892584 | Quantification of total T-cell receptor diversity by flow cytometry and spectratyping |
| Q33988097 | Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networks |
| Q73022474 | Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation |
| Q24684195 | Quantitative challenges in understanding ligand discrimination by alphabeta T cells |
| Q34212510 | Raft membrane domains and immunoreceptor functions |
| Q34245432 | Receptor clustering and transmembrane signaling in T cells |
| Q73359260 | Receptor editing (and the evolution of sex) |
| Q26795468 | Recognition of Microbial Glycolipids by Natural Killer T Cells |
| Q37068900 | Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis |
| Q55239887 | Recombinant human single-chain MHC-peptide complexes made from E. coli By in vitro refolding: functional single-chain MHC-peptide complexes and tetramers with tumor associated antigens. |
| Q43281147 | Recruitment of antigen-specific CD8+ T cells in response to infection is markedly efficient |
| Q73150513 | Regulating T helper cell immunity through antigen responsiveness and calcium entry |
| Q37717709 | Regulation of CD4 T-cell receptor diversity by vaccine adjuvants |
| Q35956830 | Regulation of T-cell receptor signalling by membrane microdomains |
| Q30413827 | Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity |
| Q43824396 | Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells |
| Q33992833 | Review article: thymus organ cultures and T-cell receptor repertoire development |
| Q34180396 | Right on target: novel approaches for the direct visualization of CD1-specific T cell responses |
| Q36368381 | Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes |
| Q40800278 | Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens |
| Q37344397 | SCHOOL model and new targeting strategies |
| Q33783983 | Selecting and maintaining a diverse T-cell repertoire |
| Q34718125 | Selection and fine-tuning of the autoimmune T-cell repertoire |
| Q74451838 | Shapes of MHC restriction |
| Q42611081 | Shared structural motifs in TCR of glycopeptide-recognizing T cell hybridomas |
| Q37084879 | Signal initiation in T-cell receptor microclusters |
| Q34778134 | Signaling in thymic selection |
| Q44473369 | Simultaneous monitoring of binding to and activation of tumor-specific T lymphocytes by peptide-MHC. |
| Q57160060 | Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges |
| Q36713758 | Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions |
| Q37155667 | Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. |
| Q41472662 | Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response |
| Q39507137 | Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains. |
| Q34492998 | So many ways of getting in the way: diversity in the molecular architecture of superantigen-dependent T-cell signaling complexes |
| Q52608113 | Soluble HIV-specific T cell receptor: expression, purification and analysis of the specificity. |
| Q34450848 | Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells |
| Q54205671 | Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system. |
| Q36137560 | Spatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells. |
| Q30488141 | Spatiotemporal patterning during T cell activation is highly diverse |
| Q34383054 | Specific increase in potency via structure-based design of a TCR. |
| Q28750407 | Src kinases are required for a balanced production of IL-12/IL-23 in human dendritic cells activated by Toll-like receptor agonists |
| Q36317151 | Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens |
| Q36958563 | Stochastic effects and bistability in T cell receptor signaling |
| Q37866944 | Strength of TCR-peptide/MHC interactions and in vivo T cell responses |
| Q27638941 | Structural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex Complexes |
| Q48355073 | Structural analysis of TCRalpha and beta chains from human T-Cell clones specific for small nuclear ribonucleoprotein polypeptides Sm-D, Sm-B and U1-70 kDa: TCR complementarity determining region 3 usage appears highly conserved |
| Q27676136 | Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction |
| Q28941762 | Structural basis for a major histocompatibility complex class Ib-restricted T cell response |
| Q33890232 | Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors |
| Q27643710 | Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1 |
| Q36376346 | Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide |
| Q34170712 | Structural, biochemical, and biophysical studies of HLA-A2/altered peptide ligands binding to viral-peptide-specific human T-cell receptors |
| Q37157256 | Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice |
| Q36362398 | Structure and function of a membrane-bound murine MHC class I molecule |
| Q27627794 | Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1 |
| Q22010160 | Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors |
| Q33947114 | Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule |
| Q37165240 | Structure-Based, Rational Design of T Cell Receptors |
| Q27639002 | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes |
| Q47260351 | Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity |
| Q41862429 | Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells |
| Q53804977 | Superantigen influence in conjunction with cytokine polymorphism potentiates autoimmunity in systemic lupus erythematosus patients. |
| Q27333772 | Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity |
| Q48252701 | Surprisingly minor influence of TRAV11 (Valpha14) polymorphism on NK T-receptor mCD1/alpha-galactosylceramide binding kinetics |
| Q35919777 | Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity |
| Q36225863 | Synaptic pattern formation during cellular recognition |
| Q43511256 | T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4. |
| Q35659205 | T Cell Receptor Engineering and Analysis Using the Yeast Display Platform |
| Q27022243 | T cell antigen recognition at the cell membrane |
| Q36967375 | T cell receptor (TCR) and transforming growth factor β (TGF-β) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation |
| Q30856414 | T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells |
| Q36404561 | T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo |
| Q74595059 | T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics |
| Q36322171 | T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation |
| Q33935247 | T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell. |
| Q30481560 | T cell receptor microcluster transport through molecular mazes reveals mechanism of translocation |
| Q33348048 | T cell receptor triggering by force |
| Q34132920 | T cell receptor-MHC interactions up close |
| Q37646853 | T cell sensitivity and the outcome of viral infection. |
| Q36439289 | T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes |
| Q40351911 | T cells specific for HPV16 E7 epitopes in patients with squamous cell carcinoma of the oropharynx |
| Q96817913 | T-Cell Mechanobiology: Force Sensation, Potentiation, and Translation |
| Q34176726 | T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model |
| Q36719329 | T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation |
| Q36467089 | T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity |
| Q36526360 | T-cell avidity and tuning: the flexible connection between tolerance and autoimmunity. |
| Q38033651 | T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction |
| Q37363263 | T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity |
| Q34572202 | T-cell regulation by CD28 and CTLA-4. |
| Q34718133 | T-cell-receptor gene therapy |
| Q52738758 | TCR Signaling: Mechanisms of Initiation and Propagation. |
| Q33849292 | TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. |
| Q77328526 | TCR binding to peptide-MHC stabilizes a flexible recognition interface |
| Q34044406 | TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo |
| Q34171867 | TCR recognition of peptide/MHC class II complexes and superantigens |
| Q93062785 | TCR repertoire and CDR3 motif analyses depict the role of αβ T cells in Ankylosing spondylitis |
| Q34078807 | TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts |
| Q38279985 | TCR signal quantity and quality in CD4(+) T cell differentiation. |
| Q43436449 | TCR v(beta) repertoire restriction and lack of CDR3 conservation implicate TCR-superantigen interactions in promoting the clonal evolution of murine thymic lymphomas |
| Q42724811 | TCR-like antibodies distinguish conformational and functional differences in two- versus four-domain auto reactive MHC class II-peptide complexes |
| Q30873107 | TCRs with high affinity for foreign pMHC show self-reactivity |
| Q33215269 | TRAV gene usage in pig T-cell receptor alpha cDNA. |
| Q37252710 | Tailoring T-cell receptor signals by proximal negative feedback mechanisms |
| Q49834468 | Targeting Intramembrane Protein-Protein Interactions: Novel Therapeutic Strategy of Millions Years Old. |
| Q37192915 | Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies |
| Q90211977 | Targeting the MHC Ligandome by Use of TCR-Like Antibodies |
| Q92127499 | Tebentafusp: T Cell Redirection for the Treatment of Metastatic Uveal Melanoma |
| Q35189911 | Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease. |
| Q40964647 | The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering. |
| Q53656560 | The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. |
| Q39817679 | The CD8+population of LAK cells can lyse both HLA-positive and HLA-negative cancer cell lines |
| Q90108763 | The Design Principles of Biochemical Timers: Circuits that Discriminate between Transient and Sustained Stimulation |
| Q36001909 | The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor. |
| Q33698006 | The Goldilocks Model for TCR—Too Much Attraction Might Not Be Best for Vaccine Design |
| Q56914786 | The Human Low Affinity Fcγ Receptors IIa, IIb, and III Bind IgG with Fast Kinetics and Distinct Thermodynamic Properties |
| Q40653197 | The Paradox of Immune Molecular Recognition of α-Galactosylceramide: Low Affinity, Low Specificity for CD1d, High Affinity for αβ TCRs |
| Q33351190 | The SCHOOL of nature: I. Transmembrane signaling |
| Q37484801 | The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition |
| Q36082282 | The TCR binding site does move |
| Q28756528 | The Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiology |
| Q38151850 | The actin-driven spatiotemporal organization of T-cell signaling at the system scale |
| Q30252521 | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status |
| Q36367978 | The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model |
| Q40794740 | The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. |
| Q33737674 | The impact of TCR-binding properties and antigen presentation format on T cell responsiveness |
| Q74312259 | The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model |
| Q35535169 | The important role of T cells and receptor expression in Sjögren's syndrome |
| Q34078621 | The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. |
| Q38026943 | The molecular determinants of CD8 co-receptor function |
| Q35073144 | The nature of molecular recognition by T cells |
| Q40831490 | The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers |
| Q34493013 | The specificity of TCR/pMHC interaction |
| Q37419923 | The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface |
| Q36122631 | Therapeutic peptidomimetic strategies for autoimmune diseases: costimulation blockade |
| Q44689533 | Thermodynamic analysis of degenerate recognition by the NKG2D immunoreceptor: not induced fit but rigid adaptation |
| Q42694508 | Thermodynamic analysis of the increased stability of major histocompatibility complex class II molecule I-Ek complexed with an antigenic peptide at an acidic pH. |
| Q35651348 | Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning |
| Q37170396 | Thermodynamics of T-cell receptor-peptide/MHC interactions: progress and opportunities |
| Q34143967 | Thirty-six views of T-cell recognition |
| Q39773899 | Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling |
| Q33816812 | Thymocyte apoptosis |
| Q33811112 | Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes |
| Q35214398 | Tumor-associated antigens: from discovery to immunity |
| Q34167226 | Two mechanisms that account for major histocompatibility complex restriction of T cells |
| Q42050788 | Two-step binding mechanism for T-cell receptor recognition of peptide MHC. |
| Q34792441 | Uncertainties - discrepancies in immunology |
| Q33683420 | Understanding the mechanism of action of bacterial superantigens from a decade of research. |
| Q91517668 | Ushering in Integrated T Cell Repertoire Profiling in Cancer |
| Q37614649 | Using Global Analysis to Extend the Accuracy and Precision of Binding Measurements with T cell Receptors and Their Peptide/MHC Ligands |
| Q36512323 | Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection |
| Q37733109 | What counts in the immunological synapse? |
| Q44666822 | Why must T cells be cross-reactive? |
| Q83061611 | microRNAs at the regulatory frontier: an investigation into how microRNAs impact the development and effector functions of CD4 T cells |
| Q24673986 | Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactiv |