T Cell Receptor Engineering and Analysis Using the Yeast Display Platform

scientific article published on January 2015

T Cell Receptor Engineering and Analysis Using the Yeast Display Platform is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/978-1-4939-2748-7_6
P932PMC publication ID5562502
P698PubMed publication ID26060072

P2093author name stringDavid M Kranz
Daniel T Harris
Sheena N Smith
P2860cites workAssembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2Q24336589
Selection of functional T cell receptor mutants from a yeast surface-display libraryQ24679820
How a T Cell Receptor-like Antibody Recognizes Major Histocompatibility Complex-bound PeptideQ27651585
Structure of the complex between human T-cell receptor, viral peptide and HLA-A2Q27733853
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedureQ28131658
Phenotypic analysis of antigen-specific T lymphocytesQ28290058
Lck availability during thymic selection determines the recognition specificity of the T cell repertoireQ28298459
The molecular basis of TCR germline bias for MHC is surprisingly simpleQ28306893
Gene splicing by overlap extension: tailor-made genes using the polymerase chain reactionQ29615257
How TCRs bind MHCs, peptides, and coreceptorsQ29619572
In vitro evolution of a T cell receptor with high affinity for peptide/MHC.Q30861962
TCRs with high affinity for foreign pMHC show self-reactivityQ30873107
Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display libraryQ30882235
Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragmentsQ41762286
Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface displayQ42019724
ImmTACs: Novel bi-specific agents for targeted cancer therapyQ43225889
Ligand recognition by alpha beta T cell receptorsQ46222293
Directed evolution of human T-cell receptors with picomolar affinities by phage display.Q51538190
Design and use of conditional MHC class I ligands.Q53637625
Directed evolution of a stable scaffold for T-cell receptor engineering.Q54045046
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiencyQ56902099
Rapid method for measuring ScFv thermal stability by yeast surface displayQ73215314
Direct phenotypic analysis of human MHC class I antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodiesQ30912466
TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity.Q31093607
Yeast surface display for directed evolution of protein expression, affinity, and stabilityQ31826513
High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.Q33211089
Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and functionQ33229925
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivityQ33239176
Isolating and engineering human antibodies using yeast surface displayQ33280948
Display, engineering, and applications of antigen-specific T cell receptorsQ33281160
Yeast surface display for protein engineering and characterizationQ33299124
High-affinity TCRs generated by phage display provide CD4+ T cells with the ability to recognize and kill tumor cell lines.Q33303162
Phage display-derived recombinant antibodies with TCR-like specificity against alpha-galactosylceramide and its analogues in complex with human CD1d moleculesQ33318487
An improved yeast transformation method for the generation of very large human antibody librariesQ33529366
Structural basis of T cell recognitionQ33652495
The impact of TCR-binding properties and antigen presentation format on T cell responsivenessQ33737674
T cell receptor engineeringQ34122119
Two mechanisms that account for major histocompatibility complex restriction of T cellsQ34167226
Monoclonal TCR-redirected tumor cell killing.Q34273053
Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responsesQ34439729
Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors.Q34626991
Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexesQ34953926
Molecular interactions mediating T cell antigen recognitionQ35077424
Dynamics of Cell Surface Molecules During T Cell RecognitionQ35550692
Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRsQ35612835
A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrationsQ36424948
Design and characterization of a protein superagonist of IL-15 fused with IL-15Rα and a high-affinity T cell receptorQ36445933
T cells as a self-referential, sensory organQ36732556
Yeast surface display for screening combinatorial polypeptide librariesQ36865126
Characterization of a single-chain T-cell receptor expressed in Escherichia coliQ37027107
Structural and biophysical insights into the role of CD4 and CD8 in T cell activationQ37030688
Evolutionarily conserved amino acids that control TCR-MHC interactionQ37096091
Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapiesQ37107843
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificityQ37363263
MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR.Q39290133
TCR mimic monoclonal antibody targets a specific peptide/HLA class I complex and significantly impedes tumor growth in vivo using breast cancer modelsQ39753463
P407language of work or nameEnglishQ1860
P304page(s)95-141
P577publication date2015-01-01
P1433published inMethods in Molecular BiologyQ15752859
P1476titleT Cell Receptor Engineering and Analysis Using the Yeast Display Platform
P478volume1319

Reverse relations

cites work (P2860)
Q38726211Affinity Maturation of a Cyclic Peptide Handle for Therapeutic Antibodies Using Deep Mutational Scanning
Q36147049Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex
Q99240741Immune literacy: reading, writing and editing adaptive immunity
Q94563407Massively parallel interrogation and mining of natively paired human TCRαβ repertoires
Q56889572Recombinant human B cell repertoires enable screening for rare, specific, and natively paired antibodies
Q47378202Tuning up T-cell receptors

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