| P50 | author | George R Young | Q42697849 |
| P2093 | author name string | George Kassiotis | |
| | Georgina Thorborn | |
| P2860 | cites work | Cutting edge: lack of high affinity competition for peptide in polyclonal CD4+ responses unmasks IL-4 production | Q41862779 |
| | Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infection | Q42613858 |
| | HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression | Q43750477 |
| | Disparate individual fates compose robust CD8+ T cell immunity | Q44525218 |
| | Heterogeneous differentiation patterns of individual CD8+ T cells. | Q44758058 |
| | Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study. | Q45023463 |
| | Impairment of immunological memory in the absence of MHC despite survival of memory T cells | Q45072920 |
| | Ligand recognition by alpha beta T cell receptors | Q46222293 |
| | Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes | Q47238652 |
| | A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes | Q48047077 |
| | The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. | Q50499734 |
| | Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory. | Q50930669 |
| | HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control. | Q51051553 |
| | Influence of CD4+CD25+ regulatory T cells on low/high-avidity CD4+ T cells following peptide vaccination. | Q51982834 |
| | Antigen-specific development of primary and memory T cells in vivo. | Q52053475 |
| | Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo. | Q53509518 |
| | In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells | Q21559398 |
| | TRIM family proteins: retroviral restriction and antiviral defence | Q24329175 |
| | Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages | Q24642180 |
| | A Blueprint for HIV Vaccine Discovery | Q26829865 |
| | A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity | Q27640322 |
| | Epitope-specific TCR repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides | Q27649750 |
| | Allelic polymorphism in the T cell receptor and its impact on immune responses | Q27662550 |
| | Differentiation of effector CD4 T cell populations (*) | Q29614838 |
| | Central memory and effector memory T cell subsets: function, generation, and maintenance | Q29615097 |
| | Active human retrotransposons: variation and disease | Q29617668 |
| | HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation | Q29619611 |
| | T-cell antigen receptor genes and T-cell recognition | Q29619721 |
| | T-cell quality in memory and protection: implications for vaccine design | Q30014840 |
| | HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity | Q33535905 |
| | The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation | Q33652505 |
| | Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection | Q33911928 |
| | Fast on-rates allow short dwell time ligands to activate T cells | Q33928549 |
| | HIV preferentially infects HIV-specific CD4+ T cells | Q33958893 |
| | Heterologous immunity between viruses | Q34051846 |
| | The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. | Q34078621 |
| | Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes | Q34162002 |
| | Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection | Q34270466 |
| | Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. | Q34285649 |
| | Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells | Q34383385 |
| | A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction | Q34384150 |
| | The peptide specificity of the endogenous T follicular helper cell repertoire generated after protein immunization | Q34450488 |
| | Early induction and maintenance of Env-specific T-helper cells following human immunodeficiency virus type 1 infection | Q34470969 |
| | High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses | Q34501474 |
| | Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens | Q34621141 |
| | Restriction of an extinct retrovirus by the human TRIM5alpha antiviral protein | Q34641314 |
| | The T-cell response to HIV. | Q34642996 |
| | Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover | Q34692601 |
| | Memory CD4 T cells that express CXCR5 provide accelerated help to B cells | Q34754506 |
| | Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells | Q34973705 |
| | Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection | Q34994754 |
| | Sequence variation in the human T-cell receptor loci | Q35030947 |
| | Escape from highly effective public CD8+ T-cell clonotypes by HIV | Q35182712 |
| | B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection | Q35215151 |
| | Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. | Q35525803 |
| | Immunological memory to viral infections. | Q35698554 |
| | Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells | Q36002596 |
| | Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation. | Q36024310 |
| | Distinct CD4+ helper T cells involved in primary and secondary responses to infection. | Q36066378 |
| | Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection | Q36073682 |
| | Stability and function of secondary Th1 memory cells are dependent on the nature of the secondary stimulus. | Q36179535 |
| | A TCR affinity threshold regulates memory CD4 T cell differentiation following vaccination | Q36179667 |
| | Expansion of HIV-specific T follicular helper cells in chronic HIV infection | Q36190755 |
| | Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling. | Q36206343 |
| | Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection | Q36239323 |
| | Bcl6 expression specifies the T follicular helper cell program in vivo | Q36278036 |
| | Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells | Q36365491 |
| | The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model | Q36365507 |
| | Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs | Q36368219 |
| | Negative selection during the peripheral immune response to antigen | Q36376090 |
| | Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. | Q36383089 |
| | Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. | Q36400784 |
| | Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response | Q36402973 |
| | T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo | Q36404561 |
| | An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro | Q36433369 |
| | Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry | Q36460244 |
| | TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection | Q36513955 |
| | Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production | Q36547664 |
| | Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR repertoire | Q36593575 |
| | Structural determinants of T-cell receptor bias in immunity | Q36655911 |
| | Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology | Q37074537 |
| | IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection | Q37085019 |
| | Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection. | Q37090620 |
| | An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a | Q37145975 |
| | Role of Nef in primate lentiviral immunopathogenesis | Q37148335 |
| | Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. | Q37155667 |
| | T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens | Q37202148 |
| | Abortive activation of CD4 T cell responses during competitive priming in vivo | Q37208979 |
| | The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding | Q37266009 |
| | Inadequate T follicular cell help impairs B cell immunity during HIV infection. | Q37349638 |
| | Race between retroviral spread and CD4+ T-cell response determines the outcome of acute Friend virus infection | Q37410816 |
| | Increasing the CD4+ T cell precursor frequency leads to competition for IFN-gamma thereby degrading memory cell quantity and quality | Q37459796 |
| | Selective up-regulation of intact, but not defective env RNAs of endogenous modified polytropic retrovirus by the Sgp3 locus of lupus-prone mice | Q37473872 |
| | Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. | Q37620444 |
| | Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. | Q37629901 |
| | HIV-1 persistence in CD4+ T cells with stem cell-like properties | Q37646541 |
| | On the composition of the preimmune repertoire of T cells specific for Peptide-major histocompatibility complex ligands | Q37715995 |
| | Role of endogenous retroviruses in murine SLE. | Q37775734 |
| | Nucleic acid recognition by the innate immune system | Q37827142 |
| | Strength of TCR-peptide/MHC interactions and in vivo T cell responses | Q37866944 |
| | How the TCR balances sensitivity and specificity for the recognition of self and pathogens. | Q37977320 |
| | A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned | Q38050479 |
| | Rules of engagement: molecular insights from host-virus arms races | Q38059240 |
| | Human T cell lymphotropic virus type I (HTLV-I)-specific CD4+ T cells: immunodominance hierarchy and preferential infection with HTLV-I. | Q39028773 |
| | Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype | Q39180411 |
| | Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens | Q39636082 |
| | Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memory | Q39852423 |
| | Vaccine adjuvants alter TCR-based selection thresholds. | Q40096549 |
| | Murine Vbeta3+ and Vbeta7+ T cell subsets are specific targets for the HERV-K18 Env superantigen | Q40241608 |
| | Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection. | Q40307170 |
| | Superantigens of mouse mammary tumor virus | Q40444910 |
| | Escape of human immunodeficiency virus from immune control | Q41464292 |
| | A kinetic basis for T cell receptor repertoire selection during an immune response | Q41649927 |
| | Sustained interactions between T cell receptors and antigens promote the differentiation of CD4⁺ memory T cells. | Q41847407 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | virology | Q7215 |
| P304 | page(s) | 27-37 | |
| P577 | publication date | 2014-07-01 | |
| P1433 | published in | Journal of Leukocyte Biology | Q1524048 |
| P1476 | title | Effective T helper cell responses against retroviruses: are all clonotypes equal? | |
| P478 | volume | 96 | |