review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Brian D Evavold | Q37370110 |
Ning Jiang | Q51089003 | ||
Veronika Zarnitsyna | Q56766137 | ||
Cheng Zhu | Q60964006 | ||
P2093 | author name string | Jun Huang | |
P2860 | cites work | T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1 | Q24296288 |
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling | Q25257443 | ||
T cell antigen recognition at the cell membrane | Q27022243 | ||
Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity | Q27333772 | ||
Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation | Q27642839 | ||
Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif | Q27652912 | ||
T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex | Q27675661 | ||
The immunological synapse: a molecular machine controlling T cell activation | Q28139151 | ||
The molecular basis of TCR germline bias for MHC is surprisingly simple | Q28306893 | ||
Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination | Q28728145 | ||
Models for the Specific Adhesion of Cells to Cells | Q29616061 | ||
Force measurements of TCR/pMHC recognition at T cell surface | Q30474720 | ||
Monitoring receptor-ligand interactions between surfaces by thermal fluctuations | Q30480925 | ||
Forcing Switch from Short- to Intermediate- and Long-lived States of the αA Domain Generates LFA-1/ICAM-1 Catch Bonds | Q30497295 | ||
Transforming binding affinities from three dimensions to two with application to cadherin clustering | Q30503964 | ||
T cell receptor triggering by force | Q33348048 | ||
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time | Q33821395 | ||
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. | Q34078621 | ||
Sensitive force technique to probe molecular adhesion and structural linkages at biological interfaces | Q34129714 | ||
Measuring two-dimensional receptor-ligand binding kinetics by micropipette | Q34168986 | ||
Kinetic proofreading in T-cell receptor signal transduction | Q34285825 | ||
Identification of self through two-dimensional chemistry and synapses. | Q34425148 | ||
High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses | Q34501474 | ||
Cell adhesion. Competition between nonspecific repulsion and specific bonding | Q34535126 | ||
Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions | Q34574696 | ||
Transport governs flow-enhanced cell tethering through L-selectin at threshold shear. | Q35220087 | ||
Analysis of two-dimensional dissociation constant of laterally mobile cell adhesion molecules | Q35606770 | ||
Mechanosensing in T lymphocyte activation | Q35679076 | ||
TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation. | Q35739705 | ||
TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity. | Q35739708 | ||
Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo | Q35925494 | ||
Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters | Q35927615 | ||
Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness | Q36009049 | ||
Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor | Q36152482 | ||
Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area. | Q36236485 | ||
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response | Q36402779 | ||
Measuring diffusion and binding kinetics by contact area FRAP. | Q36737147 | ||
A coupled diffusion-kinetics model for analysis of contact-area FRAP experiment | Q36737191 | ||
Evolutionarily conserved amino acids that control TCR-MHC interaction | Q37096091 | ||
T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity | Q37363263 | ||
Measuring Receptor-Ligand Binding Kinetics on Cell Surfaces: From Adhesion Frequency to Thermal Fluctuation Methods. | Q37408990 | ||
The alphabeta T cell receptor is an anisotropic mechanosensor. | Q37431436 | ||
Structural alterations in peptide-MHC recognition by self-reactive T cell receptors | Q37456210 | ||
Kinetic discrimination in T-cell activation | Q37715642 | ||
T cell triggering: insights from 2D kinetics analysis of molecular interactions | Q38032705 | ||
Replacing a lectin domain residue in L-selectin enhances binding to P-selectin glycoprotein ligand-1 but not to 6-sulfo-sialyl Lewis x | Q38293878 | ||
Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands | Q40487156 | ||
The immunological synapse and CD28-CD80 interactions. | Q40767962 | ||
Peptide antagonism and T cell receptor interactions with peptide-MHC complexes | Q40996486 | ||
Loss of division potential in vitro: aging or differentiation? | Q41044517 | ||
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes | Q41145528 | ||
T-cell-receptor affinity and thymocyte positive selection | Q41192128 | ||
Lack of strict correlation of functional sensitization with the apparent affinity of MHC/peptide complexes for the TCR. | Q41325800 | ||
TCR Mechanobiology: Torques and Tunable Structures Linked to Early T Cell Signaling | Q41910808 | ||
The receptor deformation model of TCR triggering | Q42058124 | ||
TCR Signaling Emerges from the Sum of Many Parts | Q42212300 | ||
A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists | Q46121537 | ||
Ligand recognition by alpha beta T cell receptors | Q46222293 | ||
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. | Q46793124 | ||
Kinetics of MHC-CD8 interaction at the T cell membrane. | Q46891783 | ||
Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion. | Q51794352 | ||
Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling. | Q54676899 | ||
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling. | Q55239901 | ||
Low affinity interaction of human or rat T cell adhesion molecule CD2 with its ligand aligns adhering membranes to achieve high physiological affinity | Q57962352 | ||
Measuring interactions of MHC class I molecules using surface plasmon resonance | Q71848145 | ||
T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity | Q72112177 | ||
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation | Q73022474 | ||
The membrane anchor influences ligand binding two-dimensional kinetic rates and three-dimensional affinity of FcgammaRIII (CD16) | Q73615825 | ||
The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model | Q74312259 | ||
T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics | Q74595059 | ||
T-cell receptor binding kinetics in T-cell development and activation | Q76384899 | ||
TCR binding to peptide-MHC stabilizes a flexible recognition interface | Q77328526 | ||
Affinity and kinetic analysis of P-selectin binding to P-selectin glycoprotein ligand-1 | Q77604437 | ||
High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling | Q77769114 | ||
Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness | Q84217956 | ||
P433 | issue | 1 | |
P304 | page(s) | 49-64 | |
P577 | publication date | 2013-01-01 | |
P1433 | published in | Immunological Reviews | Q15724582 |
P1476 | title | Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network | |
P478 | volume | 251 |
Q37614812 | 2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system. |
Q41769969 | Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling. |
Q52367953 | Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells. |
Q49966547 | Binding constant of cell adhesion receptors and substrate-immobilized ligands depends on the distribution of ligands |
Q47585396 | Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation. |
Q38682295 | Catch Bonds at T Cell Interfaces: Impact of Surface Reorganization and Membrane Fluctuations. |
Q36983760 | Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells |
Q47782025 | Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes |
Q41051986 | Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell. |
Q36119302 | Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells. |
Q26774669 | Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens |
Q64067638 | Is TCR/pMHC Affinity a Good Estimate of the T-cell Response? An Answer Based on Predictions From 12 Phenotypic Models |
Q27002652 | Linking form to function: Biophysical aspects of artificial antigen presenting cell design |
Q50963377 | Lipid rafts enhance the binding constant of membrane-anchored receptors and ligands. |
Q26781296 | Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response |
Q90168597 | Mechanosensing through immunoreceptors |
Q36977064 | Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology |
Q38626628 | Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells |
Q37637869 | Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex |
Q47625174 | Receptor-mediated cell mechanosensing. |
Q38169708 | Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset Commitment |
Q37030688 | Structural and biophysical insights into the role of CD4 and CD8 in T cell activation |
Q38671405 | TCR-ligand dissociation rate is a robust and stable biomarker of CD8+ T cell potency |
Q51371514 | Tension-compression asymmetry in the binding affinity of membrane-anchored receptors and ligands. |
Q40972761 | The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex |
Q41447071 | The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding |
Q51361915 | The glycocalyx promotes cooperative binding and clustering of adhesion receptors. |
Q35333646 | Transport regulation of two-dimensional receptor-ligand association |
Q40310220 | Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes. |
Search more.