| P50 | author | Andrew K Sewell | Q41410983 |
| P2093 | author name string | P Klenerman | |
| | L J Walker | |
| P2860 | cites work | Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus | Q24645078 |
| | Viral immune evasion due to persistence of activated T cells without effector function | Q24646943 |
| | Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes | Q24676216 |
| | Analysis of 'driver' and 'passenger' CD8+ T-cell responses against variable viruses | Q27478133 |
| | Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction | Q27481027 |
| | Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection | Q27485119 |
| | Cellular immune selection with hepatitis C virus persistence in humans | Q27485219 |
| | Increased Cytotoxic T-Lymphocyte Epitope Variant Cross-Recognition and Functional Avidity Are Associated with Hepatitis C Virus Clearance | Q27485452 |
| | A functional hot spot for antigen recognition in a superagonist TCR/MHC complex | Q27622127 |
| | Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement | Q28512242 |
| | Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes | Q29616210 |
| | The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes | Q30004698 |
| | Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen | Q32138624 |
| | Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines | Q33255244 |
| | In vivo induction of a high-avidity, high-frequency cytotoxic T-lymphocyte response is associated with antiviral protective immunity | Q33806244 |
| | T cell receptor binding kinetics and special role of Valpha in T cell development and activation | Q33942050 |
| | Discrepancy between ELISPOT IFN-gamma secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life | Q33943148 |
| | Impact of MHC class I diversity on immune control of immunodeficiency virus replication | Q34235198 |
| | Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection. | Q52027105 |
| | Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. | Q53588591 |
| | The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities. | Q53656560 |
| | Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes | Q57075675 |
| | Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia | Q57075698 |
| | From TCR Engagement to T Cell Activation | Q57363708 |
| | Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties | Q57372665 |
| | Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells | Q59078526 |
| | Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response | Q71169443 |
| | Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation | Q73022474 |
| | Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS | Q73034306 |
| | Activated TCRs remain marked for internalization after dissociation from pMHC | Q74817611 |
| | Functional avidity of tumor antigen-specific CTL recognition directly correlates with the stability of MHC/peptide multimer binding to TCR | Q77522368 |
| | Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells | Q80582126 |
| | Kinetic proofreading in T-cell receptor signal transduction | Q34285825 |
| | Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS | Q34339925 |
| | Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction | Q34570127 |
| | Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover | Q34692601 |
| | Molecular interactions mediating T cell antigen recognition | Q35077424 |
| | Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection | Q35785225 |
| | HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function | Q35834664 |
| | Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells | Q36140749 |
| | Kinetics and extent of T cell activation as measured with the calcium signal | Q36377251 |
| | Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes. | Q36400784 |
| | Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides | Q36400848 |
| | Stability and diversity of T cell receptor repertoire usage during lymphocytic choriomeningitis virus infection of mice | Q36401170 |
| | Memory of mice and men: CD8+ T-cell cross-reactivity and heterologous immunity | Q36528984 |
| | Flying under the radar: the immunobiology of hepatitis C. | Q36635544 |
| | Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface | Q36740232 |
| | Single-cell dynamics of T-cell priming | Q36791460 |
| | Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers | Q37272398 |
| | Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. | Q37629901 |
| | Kinetic discrimination in T-cell activation | Q37715642 |
| | Functional impairment of simian immunodeficiency virus-specific CD8+ T cells during the chronic phase of infection | Q39605743 |
| | Selection of high-avidity CD8 T cells correlates with control of hepatitis C virus infection | Q39949329 |
| | Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells | Q40165296 |
| | CD8 kinetically promotes ligand binding to the T-cell antigen receptor. | Q40404578 |
| | Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression | Q40618260 |
| | The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. | Q40794740 |
| | High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL. | Q40830770 |
| | The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. | Q40928275 |
| | Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition | Q41504944 |
| | Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. | Q41612272 |
| | The minimal number of class II MHC-antigen complexes needed for T cell activation | Q41724410 |
| | Role of CD8 in aberrant function of cytotoxic T lymphocytes | Q42951876 |
| | The impairment of CD8 responses limits the selection of escape mutations in acute hepatitis C virus infection | Q42996749 |
| | Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex | Q44255903 |
| | Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining | Q44619554 |
| | Functionally impaired HIV-specific CD8 T cells show high affinity TCR-ligand interactions. | Q44622912 |
| | Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection | Q45732713 |
| | CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained | Q45740431 |
| | Direct observation of ligand recognition by T cells. | Q46020608 |
| | Ligand recognition by alpha beta T cell receptors | Q46222293 |
| | The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement. | Q47817332 |
| | Molecular signature of CD8+ T cell exhaustion during chronic viral infection. | Q51970485 |
| P433 | issue | 3 | |
| P304 | page(s) | 245-255 | |
| P577 | publication date | 2009-12-01 | |
| P1433 | published in | Clinical and Experimental Immunology | Q15716708 |
| P1476 | title | T cell sensitivity and the outcome of viral infection | |
| P478 | volume | 159 | |