Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment

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Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JMB.2010.01.067
P932PMC publication ID2952653
P698PubMed publication ID20132824
P5875ResearchGate publication ID41407676

P2093author name stringJun Ye
Lin Chen
Aidong Han
Nimanthi Jayathilaka
Raja Dey
Yongqing Wu
Michael Philips
P2860cites workSolution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factorsQ22254245
Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteinsQ24290752
Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factorsQ24294604
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiationQ24305050
Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2Q24317299
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2CQ24532869
MEF-2 function is modified by a novel co-repressor, MITRQ24534397
HDAC4 deacetylase associates with and represses the MEF2 transcription factorQ24534407
p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptorQ24535129
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factorsQ24594377
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in miceQ36249548
The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesisQ36508194
Quantitative discrimination of MEF2 sitesQ36556982
Determination of the consensus binding site for MEF2 expressed in muscle and brain reveals tissue-specific sequence constraintsQ36681719
Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selectionQ37070840
Quantitative control of adaptive cardiac hypertrophy by acetyltransferase p300.Q37303806
A molecular mechanism of temperature sensitivity for mutations affecting the Drosophila muscle regulator Myocyte enhancer factor-2Q37351766
A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila.Q38292216
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.Q40252270
Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13).Q40548475
Deacetylase inhibition promotes the generation and function of regulatory T cells.Q46961808
Requirement of MADS domain transcription factor D-MEF2 for muscle formation in DrosophilaQ47072813
Drosophila MEF2, a transcription factor that is essential for myogenesisQ47072848
Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient miceQ48286983
ZDOCK: an initial-stage protein-docking algorithm.Q52015255
New genes involved in cancer identified by retroviral taggingQ74624557
Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT)Q75256528
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosisQ24599847
A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genesQ24631256
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagyQ24646352
Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2CQ24647260
Mutation of MEF2A in an inherited disorder with features of coronary artery diseaseQ24669679
Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2Q24673733
Improved methods for building protein models in electron density maps and the location of errors in these modelsQ26776980
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
Crystal structure of MEF2A core bound to DNA at 1.5 A resolutionQ27621750
Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2Q27641007
DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and ActivityQ27654868
Comparative protein modelling by satisfaction of spatial restraintsQ27860866
The CCP4 suite: programs for protein crystallographyQ27861090
The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathwayQ27939358
Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2Q28143007
Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4Q28145073
Neuronal activity-dependent cell survival mediated by transcription factor MEF2Q28146016
Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2Q28146018
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophyQ28219383
Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemiaQ28237803
MEF2: a central regulator of diverse developmental programsQ28254625
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse numberQ28297899
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathwayQ28364039
Coactivation of MEF2 by the SAP domain proteins myocardin and MASTRQ28506862
An initial blueprint for myogenic differentiationQ28588060
A Temporal Map of Transcription Factor Activity: Mef2 Directly Regulates Target Genes at All Stages of Muscle DevelopmentQ30002400
Strategies for macromolecular synchrotron crystallography.Q30305638
Control of muscle development by dueling HATs and HDACsQ34088887
The MADS-box family of transcription factorsQ34310228
Class II histone deacetylases: structure, function, and regulationQ34316258
MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber typeQ34669135
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
The steroid receptor coactivator, GRIP-1, is necessary for MEF-2C-dependent gene expression and skeletal muscle differentiation.Q35193858
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber typeQ35207780
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)520-33
P577publication date2010-03-26
P1433published inJournal of Molecular BiologyQ925779
P1476titleStructure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment
P478volume397

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cites work (P2860)
Q55263019Association genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes.
Q34461392Association of MEF2A gene polymorphisms with coronary artery disease
Q42578086Crystallization studies of the keratin-like domain from Arabidopsis thaliana SEPALLATA 3.
Q36552690DNA Shape versus Sequence Variations in the Protein Binding Process
Q27677871Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2
Q35855413Molecular cloning and in silico analysis of the duck (Anas platyrhynchos) MEF2A gene cDNA and its expression profile in muscle tissues during fetal development
Q53721148Molecular modeling and expression analysis of a MADS-box cDNA from mango (Mangifera indica L.).
Q36531785Myocyte Enhancer Factor-2A Gene Mutation and Coronary Artery Disease
Q42314462Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network
Q64062687Recursive Motif Analyses Identify Brain Epigenetic Transcription Regulatory Modules
Q42367637Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface
Q92277784Structural Basis for Plant MADS Transcription Factor Oligomerization
Q33359110Structural basis for the oligomerization of the MADS domain transcription factor SEPALLATA3 in Arabidopsis
Q27666773Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly
Q40620331The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors
Q59022252Theoretical Investigation of the D83V Mutation within the Myocyte-Specific Enhancer Factor-2 Beta and Its Role in Cancer

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