Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection

scientific article published on December 2008

Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2008.11.029
P932PMC publication ID2630178
P698PubMed publication ID19109909
P5875ResearchGate publication ID23706591

P50authorMartin HembergQ88244360
P2093author name stringMichael E Greenberg
Eirene Markenscoff-Papadimitriou
Tae-Kyung Kim
Jesse M Gray
Daniel M Bear
David A Harmin
Elizabeth J Hong
Steven W Flavell
P2860cites workSignal-dependent nuclear export of a histone deacetylase regulates muscle differentiationQ24290523
PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.Q24297205
Dendrite development regulated by CREST, a calcium-regulated transcriptional activatorQ24304307
A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiationQ24305050
Pause sites promote transcriptional termination of mammalian RNA polymerase IIQ24548945
A large-scale analysis of mRNA polyadenylation of human and mouse genesQ24557438
A gene atlas of the mouse and human protein-encoding transcriptomesQ24568043
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosisQ24599847
Genome-wide maps of chromatin state in pluripotent and lineage-committed cellsQ24632506
The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctionsQ24644466
Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous systemQ24650727
Developmental remodeling of the retinogeniculate synapseQ49063133
Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.Q52046731
Jumonji represses alpha-cardiac myosin heavy chain expression via inhibiting MEF2 activity.Q52056420
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sitesQ24653978
Identifying autism loci and genes by tracing recent shared ancestryQ24655308
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor traffickingQ24681745
Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1aQ28187839
Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament systemQ28206200
MEF2: a central regulator of diverse developmental programsQ28254625
Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmissionQ28264840
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse numberQ28297899
Differential effects of PACAP-38 on synaptic responses in rat hippocampal CA1 regionQ28360969
MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and functionQ28507026
Activity-dependent regulation of inhibitory synapse development by Npas4Q28510423
Regulation of thalamocortical patterning and synaptic maturation by NeuroD2Q28512025
A role in learning for SRF: deletion in the adult forebrain disrupts LTD and the formation of an immediate memory of a novel contextQ28585852
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuliQ28591800
AMPA receptor trafficking and synaptic plasticityQ29547876
Kinesin transports RNA: isolation and characterization of an RNA-transporting granuleQ29618417
Rap2-JNK removes synaptic AMPA receptors during depotentiationQ30437110
Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory.Q30489623
Immunohistochemical localization of the voltage-gated potassium channel subunit Kv1.4 in the central nervous system of the adult rat.Q30664424
Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions.Q33210386
X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairmentQ34591768
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
Neural activity and the dynamics of central nervous system developmentQ35719203
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient miceQ36013388
Enriched environments, experience-dependent plasticity and disorders of the nervous system.Q36573332
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effectsQ36586953
Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinasesQ36713956
SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viabilityQ42477944
Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic captureQ43917165
Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axonQ44222201
Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.Q44610930
Type 8 Adenylyl Cyclase Is Targeted to Excitatory Synapses and Required for Mossy Fiber Long-Term PotentiationQ44636991
A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis.Q44740477
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites.Q48403230
Effects of visual experience on activity-dependent gene regulation in cortexQ48595984
Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical culturesQ48683647
Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors.Q48703336
A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memoriesQ48971377
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1022-1038
P577publication date2008-12-01
P1433published inNeuronQ3338676
P1476titleGenome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection
P478volume60

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cites work (P2860)
Q395014173'READS+, a sensitive and accurate method for 3' end sequencing of polyadenylated RNA.
Q90615443A Developmental Program Truncates Long Transcripts to Temporally Regulate Cell Signaling
Q46740041A Functional Role for the Epigenetic Regulator ING1 in Activity-induced Gene Expression in Primary Cortical Neurons.
Q64278585A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2
Q43149079A boost in microRNAs shapes up the neuron
Q33920412A change-point model for identifying 3'UTR switching by next-generation RNA sequencing
Q24608565A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation
Q38994476A network-biology perspective of microRNA function and dysfunction in cancer
Q53064573A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors.
Q41904035A role for CaV1 and calcineurin signaling in depolarization-induced changes in neuronal DNA methylation.
Q33756913A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination
Q35588119A transcriptional program promotes remodeling of GABAergic synapses in Caenorhabditis elegans
Q34346685ATM and the epigenetics of the neuronal genome
Q48650338Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons
Q46559090Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation.
Q38074584Activity-dependent neuronal signalling and autism spectrum disorder
Q34370550Alteration of imprinted Dlk1-Dio3 miRNA cluster expression in the entorhinal cortex induced by maternal immune activation and adolescent cannabinoid exposure
Q36063269Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease
Q36824347Alterations in polyadenylation and its implications for endocrine disease
Q46306804Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes
Q47095849Alternative Polyadenylation: Methods, Findings, and Impacts
Q47839926Alternative Splicing of Alpha- and Beta-Synuclein Genes Plays Differential Roles in Synucleinopathies.
Q35902018Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control
Q34037217Alternative cleavage and polyadenylation: extent, regulation and function
Q26864222Alternative cleavage and polyadenylation: the long and short of it
Q37350682Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil
Q33621511Alternative polyadenylation diversifies post-transcriptional regulation by selective RNA-protein interactions.
Q27027041Alternative polyadenylation in the nervous system: to what lengths will 3' UTR extensions take us?
Q33832891Alternative polyadenylation of mRNA precursors.
Q91834625Alternative polyadenylation produces multiple 3' untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons
Q38238678Alternative polyadenylation: less than meets the eye?
Q36418590Alternative polyadenylation: new insights from global analyses
Q37649232Alternative pre-mRNA splicing in neurons: growing up and extending its reach
Q37048054An epigenetic mechanism mediates developmental nicotine effects on neuronal structure and behavior.
Q33791880An inside job: how endosomal Na(+)/H(+) exchangers link to autism and neurological disease
Q37652978An unexpected ending: noncanonical 3' end processing mechanisms.
Q42348646Analyses of alternative polyadenylation: from old school biochemistry to high-throughput technologies.
Q36106993Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq
Q36575994Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing.
Q92407662Analysis of alternative cleavage and polyadenylation in mature and differentiating neurons using RNA-seq data
Q38271962Angelman syndrome: advancing the research frontier of neurodevelopmental disorders
Q90251211Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures
Q93165151Anxiolytic and Anxiogenic? How the Transcription Factor MEF2 Might Explain the Manifold Behavioral Effects of Oxytocin
Q38031004Autism genetics: searching for specificity and convergence
Q27320813Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling
Q42370459BAC transgenic mice reveal distal cis-regulatory elements governing BDNF gene expression
Q35190887BAC-based cellular model for screening regulators of BDNF gene transcription.
Q56831608Bioinformatics Tools for Next-Generation RNA Sequencing Analysis
Q90718352CAIII expression in skeletal muscle is regulated by Ca2+-CaMKII-MEF2C signaling
Q41377606CD5 expression is regulated during human T-cell activation by alternative polyadenylation, PTBP1, and miR-204
Q41933268CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development
Q52714934Cell Cycle Regulation by Alternative Polyadenylation of CCND1.
Q55346318Cellular stress alters 3'UTR landscape through alternative polyadenylation and isoform-specific degradation.
Q61449468Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors
Q39269835Cleavage and polyadenylation: Ending the message expands gene regulation
Q28569311Cocaine induces the expression of MEF2C transcription factor in rat striatum through activation of SIK1 and phosphorylation of the histone deacetylase HDAC5
Q46306192Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe
Q34706714Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq
Q36406376Context-dependent modulation of Pol II CTD phosphatase SSUP-72 regulates alternative polyadenylation in neuronal development
Q28652392Core and region-enriched networks of behaviorally regulated genes and the singing genome
Q46684610Coupling cellular metabolism to neuronal signalling.
Q64917651Crosstalk between alternative polyadenylation and miRNAs in the regulation of protein translational efficiency.
Q55279990Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types.
Q28571349Differential effects of binge methamphetamine injections on the mRNA expression of histone deacetylases (HDACs) in the rat striatum
Q34867927Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing.
Q58097390Distinct Expression Pattern of Epigenetic Machinery Genes in Blood Leucocytes and Brain Cortex of Depressive Patients
Q41630070Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.
Q41691925Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D
Q39090047Dynamic landscape of alternative polyadenylation during retinal development
Q41684291Dysregulation of Alternative Poly-adenylation as a Potential Player in Autism Spectrum Disorder
Q36331360ELAV mediates 3' UTR extension in the Drosophila nervous system
Q34917978Early phase of plasticity-related gene regulation and SRF dependent transcription in the hippocampus
Q38116091Emerging roles for MEF2 transcription factors in memory
Q49646234Emerging themes in neuronal activity-dependent gene expression
Q36835360Endothelial Aquaporin-1 (AQP1) Expression Is Regulated by Transcription Factor Mef2c
Q34292008Enhancer RNA facilitates NELF release from immediate early genes
Q38644580Evolution and Biological Roles of Alternative 3'UTRs
Q28596593Evolution of Osteocrin as an activity-regulated factor in the primate brain
Q47132310Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c
Q28730816Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques
Q24633200Extensive alternative polyadenylation during zebrafish development
Q39063317FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination
Q40220770FMRP: a triple threat to PSD-95.
Q34324573Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal
Q55499041Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity.
Q28590430FoxO6 regulates memory consolidation and synaptic function
Q40372504Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.
Q33567755From neural development to cognition: unexpected roles for chromatin
Q37825465Functional genomics of the brain: uncovering networks in the CNS using a systems approach
Q34390588Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells
Q39167599Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders.
Q36738343Genome-Wide Association and Exome Sequencing Study of Language Disorder in an Isolated Population
Q26992052Genome-wide alternative polyadenylation in animals: insights from high-throughput technologies
Q29416996Genome-wide association analysis identifies susceptibility loci for migraine without aura
Q39328196Genome-wide epigenetic analysis of MEF2A and MEF2C transcription factors in mouse cortical neurons
Q33594328Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways
Q35134212Genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation.
Q42107685Genome-wide maps of polyadenylation reveal dynamic mRNA 3'-end formation in mammalian cell lineages
Q29417021Genome-wide meta-analysis identifies new susceptibility loci for migraine
Q47119901Genome-wide prediction of DNase I hypersensitivity using gene expression
Q35023002Genome-wide profiling of the activity-dependent hippocampal transcriptome
Q38189521Gephyrin: a master regulator of neuronal function?
Q35545891Global and quantitative profiling of polyadenylated RNAs using PAS-seq
Q36147160Glucocorticoid receptor and myocyte enhancer factor 2 cooperate to regulate the expression of c-JUN in a neuronal context
Q28535389HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo
Q41209497HDAC4 governs a transcriptional program essential for synaptic plasticity and memory
Q33838515Heterogeneity in mammalian RNA 3' end formation
Q30473855Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?
Q37809823Hippocampal gene profiling: toward a systems biology of the hippocampus
Q24299384Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors
Q37584846How voltage-gated calcium channels gate forms of homeostatic synaptic plasticity
Q34322973Human brain evolution: transcripts, metabolites and their regulators
Q35879587IVT-SAPAS: Low-Input and Rapid Method for Sequencing Alternative Polyadenylation Sites
Q58763990Identification and Characterization of Transcripts Regulated by Circadian Alternative Polyadenylation in Mouse Liver
Q83515859Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene
Q83231039Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq
Q38550206Immune mediators in the brain and peripheral tissues in autism spectrum disorder
Q89184196In Vivo and In Vitro Neuronal Plasticity Modulation by Epigenetic Regulators
Q28508411In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival
Q36299874Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo
Q27023529Interactions between mitochondria and the transcription factor myocyte enhancer factor 2 (MEF2) regulate neuronal structural and functional plasticity and metaplasticity
Q37001441Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA
Q36419883Ketamine produces antidepressant-like effects through phosphorylation-dependent nuclear export of histone deacetylase 5 (HDAC5) in rats
Q41579833LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation.
Q27025293La FAM fatale: USP9X in development and disease
Q28741951Language development after cochlear implantation: an epigenetic model
Q84497066Language evolution to revolution: the leap from rich-vocabulary non-recursive communication system to recursive language 70,000 years ago was associated with acquisition of a novel component of imagination, called Prefrontal Synthesis, enabled by a m
Q28829869Large-Scale Production of Mature Neurons from Human Pluripotent Stem Cells in a Three-Dimensional Suspension Culture System
Q57295921Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function
Q48411990MEF2 negatively regulates learning-induced structural plasticity and memory formation
Q49735398MEF2 signaling and human diseases.
Q26778515MEF2 transcription factors: developmental regulators and emerging cancer genes
Q97884887MEF2C and HDAC5 regulate Egr1 and Arc genes to increase dendritic spine density and complexity in early enriched environment
Q45051337MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Q39515862MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers
Q37128147MHCI requires MEF2 transcription factors to negatively regulate synapse density during development and in disease
Q30826698MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors
Q35100259Mechanisms of specificity in neuronal activity-regulated gene transcription
Q33874584Meeting at the crossroads: common mechanisms in Fragile X and Down syndrome
Q36367305Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization
Q38963722Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
Q42627275MicroRNA as modulators of neuronal responses
Q24318325MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease
Q26744408MicroRNA: Small RNA mediators of the brains genomic response to environmental stress
Q38126970Migraine genetics: Part II.
Q28729893Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives
Q37417041Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation.
Q42614366Molecular cloning and characterization of a putative proline dehydrogenase gene in the Colorado potato beetle, Leptinotarsa decemlineata
Q55114672Multilevel Differential Control of Hormone Gene Expression Programs by hnRNP L and LL in Pituitary Cells.
Q24306675Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95
Q57059733Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells
Q40463837Myocyte-specific enhancer binding factor 2A expression is downregulated during temporal lobe epilepsy.
Q47279488Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders
Q92668133Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice
Q34183712Neuronal activity-regulated gene transcription in synapse development and cognitive function
Q34377554Neuroprotective activity of pDING in response to HIV-1 Tat.
Q34567939New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases
Q37031010Npas4 is a novel activity-regulated cytoprotective factor in pancreatic β-cells.
Q33899506Nuclear pre-mRNA 3'-end processing regulates synapse and axon development in C. elegans
Q89602927Nuclear receptor corepressors in intellectual disability and autism
Q41288601Oleanolic Acid Promotes Neuronal Differentiation and Histone Deacetylase 5 Phosphorylation in Rat Hippocampal Neurons
Q28572838Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation
Q36017267Oxytocin Regulates Stress-Induced Crf Gene Transcription through CREB-Regulated Transcription Coactivator 3
Q39293515PACAP38: Emerging Drug Target in Migraine and Cluster Headache
Q40844180Part I: Pituitary adenylate cyclase-activating polypeptide-38 induced migraine-like attacks in patients with and without familial aggregation of migraine
Q40844188Part II: Biochemical changes after pituitary adenylate cyclase-activating polypeptide-38 infusion in migraine patients
Q60932964Pathogenic Feed-Forward Mechanisms in Alzheimer's and Parkinson's Disease Converge on GSK-3
Q38106687Pearls and pitfalls in genetic studies of migraine
Q47119633PolyA_DB 3 catalogs cleavage and polyadenylation sites identified by deep sequencing in multiple genomes
Q28568965Polyadenylation site-specific differences in the activity of the neuronal βCstF-64 protein in PC-12 cells
Q58698172Post-transcriptional Processing of mRNA in Neurons: The Vestiges of the RNA World Drive Transcriptome Diversity
Q47605317Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNA-Binding Protein Syncrip.
Q37693565Pre-mRNA 3'-end processing complex assembly and function
Q26746120Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end
Q38125942Protein sumoylation in brain development, neuronal morphology and spinogenesis.
Q41834634Quantitative Nucleotide Level Analysis of Regulation of Translation in Response to Depolarization of Cultured Neural Cells
Q36002383RAX2: a genome-wide detection method of condition-associated transcription variation.
Q34788864RNA-binding proteins in pluripotency, differentiation, and reprogramming.
Q91942578Regulation and Function of Activity-Dependent Homer in Synaptic Plasticity
Q38858919Regulation of Tissue-Specific Alternative Splicing: C. elegans as a Model System
Q35955726Regulation of cytoplasmic mRNA decay
Q37899389Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins
Q50078213Rem2 signaling affects neuronal structure and function in part by regulation of gene expression.
Q33520920Reprogramming of 3' untranslated regions of mRNAs by alternative polyadenylation in generation of pluripotent stem cells from different cell types
Q47752204Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease
Q46538398Roles of RNA-binding Proteins and Post-transcriptional Regulation in Driving Male Germ Cell Development in the Mouse
Q60918255Single-Cell RNA-Seq of Mouse Olfactory Bulb Reveals Cellular Heterogeneity and Activity-Dependent Molecular Census of Adult-Born Neurons
Q47734878Small Nuclear Ribonucleoprotein Polypeptide A-Mediated Alternative Polyadenylation of STAT5B during Th1 Cell Differentiation
Q35002793Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory
Q92626279Stiff matrix instigates type I collagen biogenesis by mammalian cleavage factor I complex-mediated alternative polyadenylation
Q34502652Stimulus-specific combinatorial functionality of neuronal c-fos enhancers
Q30651908Store-operated calcium entry promotes the degradation of the transcription factor Sp4 in resting neurons
Q24313447Structural basis of UGUA recognition by the Nudix protein CFI(m)25 and implications for a regulatory role in mRNA 3' processing
Q27659516Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment
Q37086805Sumoylated MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons.
Q48646891Suppression of a MEF2-KLF6 survival pathway by PKA signaling promotes apoptosis in embryonic hippocampal neurons.
Q35532398Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation
Q49721275Targeted Pituitary Adenylate Cyclase-Activating Peptide Therapies for Migraine
Q89091485Targeting Kruppel-like Factor 9 in Excitatory Neurons Protects against Chronic Stress-Induced Impairments in Dendritic Spines and Fear Responses
Q33744301The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.
Q36182348The Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice
Q37020202The Drosophila transcription factor Adf-1 (nalyot) regulates dendrite growth by controlling FasII and Staufen expression downstream of CaMKII and neural activity
Q38080479The MEF2 family and the brain: from molecules to memory
Q42183498The MEF2C-Related and 5q14.3q15 Microdeletion Syndrome.
Q35313641The Mef2A transcription factor coordinately regulates a costamere gene program in cardiac muscle
Q38113966The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture
Q28538471The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs
Q46262964The Secret Life of RNA: Lessons from Emerging Methodologies
Q53079998The antidepressant action of 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid is mediated by phosphorylation of histone deacetylase 5.
Q28082339The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site
Q91942357The first year
Q33686078The function of activity-regulated genes in the nervous system.
Q38151716The genetic landscape of autism spectrum disorders
Q35071111The histone deacetylase HDAC4 regulates long-term memory in Drosophila
Q38220786The neuronal activity-driven transcriptome.
Q33826903The polyadenylation code: a unified model for the regulation of mRNA alternative polyadenylation
Q26750643The reciprocal regulation between splicing and 3'-end processing
Q35647390The role of CYP3A4 mRNA transcript with shortened 3'-untranslated region in hepatocyte differentiation, liver development, and response to drug induction.
Q33878539The transcription factor Mef2 is required for normal circadian behavior in Drosophila
Q37382974The transcription factor Mef2 links the Drosophila core clock to Fas2, neuronal morphology, and circadian behavior
Q98729618The transcriptional elongation rate regulates alternative polyadenylation in yeast
Q39801587The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus
Q39296630Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development
Q47974836Transcription Factors: Potential Cell Death Markers in Parkinson's Disease
Q38603201Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Q35458713Transcriptional activity regulates alternative cleavage and polyadenylation
Q26996475Transcriptional co-repressors and memory storage
Q22241120Transcriptional mechanisms of drug addiction
Q95592005Transcriptional mechanisms of drug addiction
Q34222337Transcriptional regulation of neuronal polarity and morphogenesis in the mammalian brain
Q36414738Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation
Q34249424Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action
Q38016101Translational control by changes in poly(A) tail length: recycling mRNAs.
Q24623251U1 snRNP determines mRNA length and regulates isoform expression
Q92480757U1 snRNP regulates cancer cell migration and invasion in vitro
Q36684834UV damage regulates alternative polyadenylation of the RPB2 gene in yeast.
Q37309705Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression
Q34236650Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism
Q29615863Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
Q29614330Widespread transcription at neuronal activity-regulated enhancers
Q47802335cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.
Q24601240mRNA 3'end processing: A tale of the tail reaches the clinic
Q90045698miRNA-dependent regulation of STIM1 expression in breast cancer
Q84979636α-synuclein aggregation reduces nigral myocyte enhancer Factor-2D in idiopathic and experimental Parkinson's disease

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