Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D

scientific article published on 13 September 2017

Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.26278
P932PMC publication ID5608508
P698PubMed publication ID28901289

P50authorJulia E R WilkersonQ78305820
Kimberly M HuberQ95336445
Chia-Wei ChangQ96246741
P2093author name stringCarly F Hale
Jay R Gibson
P2860cites workMultiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95Q24306675
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In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survivalQ28508411
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A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse eliminationQ33756913
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Long-term sensory deprivation prevents dendritic spine loss in primary somatosensory cortexQ34433739
Homeostatic scaling requires group I mGluR activation mediated by Homer1aQ34455735
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Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
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Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rateQ36966248
Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.Q37025074
Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons.Q37068389
Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selectionQ37070840
MHCI requires MEF2 transcription factors to negatively regulate synapse density during development and in diseaseQ37128147
Postsynaptic FMRP promotes the pruning of cell-to-cell connections among pyramidal neurons in the L5A neocortical networkQ37603793
Mechanisms and functions of theta rhythmsQ38110906
Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.Q40372504
Arc/Arg3.1 is a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum.Q41779911
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptorsQ41825065
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MEF2 negatively regulates learning-induced structural plasticity and memory formationQ48411990
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P577publication date2017-09-13
P1433published ineLifeQ2000008
P1476titleDistinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D
P478volume6

Reverse relations

cites work (P2860)
Q64278585A Late Phase of Long-Term Synaptic Depression in Cerebellar Purkinje Cells Requires Activation of MEF2
Q52626735MEF2A regulates mGluR-dependent AMPA receptor trafficking independently of Arc/Arg3.1.
Q92668133Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice
Q47752204Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease

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