Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo

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Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1096/FJ.15-275651
P8608Fatcat IDrelease_moflc2chizfchevkck5z2vbtli
P932PMC publication ID4653059
P698PubMed publication ID26286136
P5875ResearchGate publication ID281813090

P50authorAmelia J EischQ56502799
P2093author name stringJenny Hsieh
David P Petrik
Sarah E Latchney
Yindi Jiang
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Adult neurogenesis and dendritic remodeling in hippocampal plasticity: which one is more important?Q38196513
Postnatal neurogenesis and gliogenesis in the olfactory bulb from NG2-expressing progenitors of the subventricular zone.Q38334176
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinasesQ39729499
Doublecortin-positive newly born granule cells of hippocampus have abnormal apical dendritic morphology in the pilocarpine model of temporal lobe epilepsy.Q39806372
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Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levelsQ43079834
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Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain.Q46402795
Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionatorQ48095561
Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesisQ48132703
Isolation and culture of adult neurons and neurospheresQ48147846
MEF2 negatively regulates learning-induced structural plasticity and memory formationQ48411990
Unbiased stereological estimation of the number of neurons in the human hippocampusQ48956996
Cre recombinase specificity defined by the tau locus.Q50789054
Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturationQ71978735
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A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiationQ24305050
Adult neurogenesis in the mammalian brain: significant answers and significant questionsQ24628935
Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivoQ24644531
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Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.Q24804951
Structural plasticity of dendritic spinesQ27002957
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Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse numberQ28297899
MEF2C transcription factor controls chondrocyte hypertrophy and bone developmentQ28505927
MEF2C, a transcription factor that facilitates learning and memory by negative regulation of synapse numbers and functionQ28507026
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Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2CQ28589290
Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cellsQ28591351
Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampusQ30583645
Monosynaptic inputs to new neurons in the dentate gyrus.Q30667853
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosisQ33560182
Notch1 is required for maintenance of the reservoir of adult hippocampal stem cellsQ34112161
Dendritic arbor development and synaptogenesisQ34141484
Non-cell-autonomous factor induces the transition from excitatory to inhibitory GABA signaling in retina independent of activityQ34438429
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memoryQ35002793
Opiates inhibit neurogenesis in the adult rat hippocampusQ35163722
Deletion of the NMDA receptor GluN2A subunit significantly decreases dendritic growth in maturing dentate granule neuronsQ35217021
Adult hippocampal neurogenesis and plasticity in the infrapyramidal bundle of the mossy fiber projection: I. Co-regulation by activityQ35233523
Neurod1 is essential for the survival and maturation of adult-born neuronsQ36002263
Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule.Q36117399
Regulation of dendritic branching by Cdc42 GAPsQ36162649
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in miceQ36249548
Genetic influence on neurogenesis in the dentate gyrus of adult miceQ36587102
Determination of the consensus binding site for MEF2 expressed in muscle and brain reveals tissue-specific sequence constraintsQ36681719
Homeostatic signaling: the positive side of negative feedbackQ36798818
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectneurogenesisQ1456827
P304page(s)5059-5071
P577publication date2015-08-18
P1433published inFASEB JournalQ520194
P1476titleInducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo
P478volume29

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cites work (P2860)
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Q35900185Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice
Q55314869The transcription factor MEF2A plays a key role in the differentiation/maturation of rat neural stem cells into neurons.
Q47974836Transcription Factors: Potential Cell Death Markers in Parkinson's Disease
Q58772354is essential for normal mushroom body and wing development

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