Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4

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Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/EMBOJ.2010.101
P932PMC publication ID2892363
P698PubMed publication ID20512114
P5875ResearchGate publication ID44639294

P50authorJessica BrownQ91252959
P2093author name stringPaul Blum
Takehiko Nohmi
Hong Ling
Zucai Suo
Jimson H Y Wong
P2860cites workTesting electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion holeQ21146064
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Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replicationQ27635332
Replication of a cis-syn thymine dimer at atomic resolutionQ27641791
A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignmentQ27648053
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase etaQ27648988
In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenicQ45770163
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The Efficiency and Fidelity of Translesion Synthesis past Cisplatin and Oxaliplatin GpG Adducts by Human DNA Polymerase βQ62571313
Enhanced replicative bypass of platinum-DNA adducts in cisplatin-resistant human ovarian carcinoma cell linesQ72018747
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An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active siteQ83157055
Site selectivity of platinum anticancer therapeuticsQ27649414
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4Q27650489
Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase ιQ27655470
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Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymeraseQ30535279
Replication of damaged DNA in mammalian cells: new solutions to an old problemQ30746296
A systematic proteomic study of seed filling in soybean. Establishment of high-resolution two-dimensional reference maps, expression profiles, and an interactive proteome database.Q31159210
A role for polymerase eta in the cellular tolerance to cisplatin-induced damageQ33226488
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammalsQ33400985
Molecular characterization of the alpha-glucosidase gene (malA) from the hyperthermophilic archaeon Sulfolobus solfataricus.Q33726067
Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysisQ33947166
Error-prone repair DNA polymerases in prokaryotes and eukaryotesQ34131455
DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS geneQ34214203
Cisplatin: from DNA damage to cancer chemotherapy.Q34348474
Mechanism of a genetic glissando: structural biology of indel mutations.Q34503186
Targeted disruption of the alpha-amylase gene in the hyperthermophilic archaeon Sulfolobus solfataricusQ34580851
Extragenic pleiotropic mutations that repress glycosyl hydrolase expression in the hyperthermophilic archaeon Sulfolobus solfataricus.Q34607503
Specialized DNA polymerases, cellular survival, and the genesis of mutationsQ34662609
Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon Sulfolobus solfataricus by use of gene disruptionQ34674956
Molecular mechanisms of resistance and toxicity associated with platinating agentsQ35758048
What a difference a decade makes: insights into translesion DNA synthesisQ36023692
Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?Q36149816
Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymeraseQ36777842
Activation of programmed cell death by anticancer agents: cisplatin as a model systemQ37974752
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypassQ38304415
Single d(GpG)/cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerizationQ38329470
Roles of DnaK and RpoS in starvation-induced thermotolerance of Escherichia coliQ39564605
Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA.Q39826836
Role of DNA replication in carrier-ligand-specific resistance to platinum compounds in L1210 cellsQ41654950
Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal formQ43547500
Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II) in murine leukemia L1210 cells.Q44220203
Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta.Q44280407
Efficiency of extension of mismatched primer termini across from cisplatin and oxaliplatin adducts by human DNA polymerases beta and eta in vitroQ44670382
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2059-69
P577publication date2010-06-16
P1433published inThe EMBO JournalQ1278554
P1476titleStructural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4
P478volume29

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cites work (P2860)
Q98465470A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota
Q52332039A transcriptional factor B paralog functions as an activator to DNA damage-responsive expression in archaea.
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Q27675603Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase
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Q35213112Roles of the four DNA polymerases of the crenarchaeon Sulfolobus solfataricus and accessory proteins in DNA replication
Q27678933Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy
Q34467599Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.
Q27678705Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.
Q34509062Translesion DNA Synthesis
Q36932640Translesion synthesis past guanine(C8)-thymine(N3) intrastrand cross-links catalyzed by selected A- and Y-family polymerases
Q38543056Understanding DNA Repair in Hyperthermophilic Archaea: Persistent Gaps and Other Reasons to Focus on the Fork

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