Structural Characterization of the Stem–Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone

scientific article published on September 25, 2010

Structural Characterization of the Stem–Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JMB.2010.09.036
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0022283610010247?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0022283610010247?httpAccept=text/xml
P3181OpenCitations bibliographic resource ID1658872
P698PubMed publication ID20875426
P5875ResearchGate publication ID46577625

P50authorVincent GoffinQ88290259
Isabelle BroutinQ92815332
Patrick EnglandQ28322928
Bertrand RaynalQ28322932
Sylviane HoosQ28322935
P2093author name stringChi Zhang
Bruno Baron
Estelle Tallet
Jan van Agthoven
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Crystal Structure of an Affinity-matured Prolactin Complexed to Its Dimerized Receptor Reveals the Topology of Hormone Binding Site 2Q27646645
Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRLQ27647816
Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptorQ27650572
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Structure and function of a new class of human prolactin antagonistsQ37227315
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Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathwayQ40148703
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Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptorsQ40588516
Role of tryptophan-tryptophan interactions in Trpzip beta-hairpin formation, structure, and stabilityQ43269718
Role of prolactin/prolactin receptor signaling in human breast cancer.Q45248782
An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.Q46589328
Ligand-independent dimerization of the human prolactin receptor isoforms: functional implicationsQ50335953
Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions.Q50721761
Ligand-independent homo- and heterodimerization of human prolactin receptor variants: inhibitory action of the short forms by heterodimerization.Q50735815
Local over-expression of prolactin in differentiating mouse mammary gland induces functional defects and benign lesions, but no carcinoma.Q54588060
Solution Structure of Human ProlactinQ58045319
Real-time kinetic measurements of the interactions between lactogenic hormones and prolactin-receptor extracellular domains from several species support the model of hormone-induced transient receptor dimerizationQ71515019
The role of receptor dimerization domain residues in growth hormone signalingQ73067623
Prolactin receptor antagonistsQ77731102
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectprotein multimerizationQ60439578
P304page(s)112-26
P577publication date2010-09-25
2010-11-19
P1433published inJournal of Molecular BiologyQ925779
P1476titleStructural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone
Structural Characterization of the Stem–Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone
P478volume404

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cites work (P2860)
Q35583040A Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase Signaling
Q39770160A combined computational and structural model of the full-length human prolactin receptor
Q27331774A common model for cytokine receptor activation: combined scissor-like rotation and self-rotation of receptor dimer induced by class I cytokine
Q93177352Association of prolactin receptor (PRLR) variants with prolactinomas
Q50551548Cloning, expression of, and evidence of positive selection for, the prolactin receptor gene in Chinese giant salamander (Andrias davidianus).
Q57252653Cytokine Receptors
Q35542930Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling
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Q36509470Understanding cytokine and growth factor receptor activation mechanisms

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