Template-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolution

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Template-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolution is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201007081
P932PMC publication ID3003314
P698PubMed publication ID20974813
P5875ResearchGate publication ID47544252

P50authorCarolyn A MooresQ41612482
Mylène PerderisetQ125267371
Franck J FourniolQ125267438
Béatrice AmiguesQ125267474
Anne Houdusse-JuilléQ15845472
Fiona FrancisQ28468816
P2093author name stringCharles V Sindelar
Daniel K Clare
Geraint Thomas
P2860cites workLattice structure of cytoplasmic microtubules in a cultured Mammalian cellQ30491956
The evolving doublecortin (DCX) superfamilyQ30820710
Axon extension occurs independently of centrosomal microtubule nucleation.Q33522528
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humansQ34600929
Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).Q34640484
Microtubules: evidence for 13 protofilamentsQ34700150
Gamma-tubulin distribution in the neuron: implications for the origins of neuritic microtubulesQ36531950
Mechanism of microtubule stabilization by doublecortinQ38575732
Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegansQ41376858
Lattice defects in microtubules: protofilament numbers vary within individual microtubulesQ41635364
Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonateQ42771172
Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules.Q46016742
Straight GDP-tubulin protofilaments form in the presence of taxolQ46963490
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.Q47967639
The Schizosaccharomyces pombe EB1 Homolog Mal3p Binds and Stabilizes the Microtubule Lattice SeamQ57873710
PHOELIX: a package for semi-automated helical reconstructionQ63258838
Microtubule structure at 8 A resolutionQ78364964
Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidanceQ24294967
Doublecortin microtubule affinity is regulated by a balance of kinase and phosphatase activity at the leading edge of migrating neuronsQ24306132
Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyriaQ24313546
A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndromeQ24314944
An atomic-level mechanism for activation of the kinesin molecular motorsQ24625687
Direct visualization of the microtubule lattice seam both in vitro and in vivoQ24673052
Refined structure of alpha beta-tubulin at 3.5 A resolutionQ27636088
The DCX-domain tandems of doublecortin and doublecortin-like kinaseQ27640972
The beginning of kinesin's force-generating cycle visualized at 9-A resolutionQ27644653
9-Angström structure of a microtubule-bound mitotic motorQ27654097
Variations in the colchicine-binding domain provide insight into the structural switch of tubulinQ27656945
Structure of the alpha beta tubulin dimer by electron crystallographyQ27748784
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
Comparative protein modelling by satisfaction of spatial restraintsQ27860866
Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetryQ27936657
Microtubule polymerization dynamicsQ28259930
Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling proteinQ28263735
Ab initio resolution measurement for single particle structuresQ28267596
FREALIGN: high-resolution refinement of single particle structuresQ30080020
Protein structure fitting and refinement guided by cryo-EM densityQ30367773
Structural basis of interprotofilament interaction and lateral deformation of microtubulesQ30431088
Distinct roles of doublecortin modulating the microtubule cytoskeleton.Q30478042
Spinophilin facilitates dephosphorylation of doublecortin by PP1 to mediate microtubule bundling at the axonal wrist.Q30479752
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule latticeQ30484323
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
microtubuleQ189933
visualizationQ451553
P304page(s)463-70
P577publication date2010-11-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleTemplate-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolution
P478volume191

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cites work (P2860)
Q27012425+TIPs: SxIPping along microtubule ends
Q46075285A MAP holds the corners.
Q27670696A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
Q89944955A doublecortin-domain protein of Toxoplasma and its orthologues bind to and modify the structure and organization of tubulin polymers
Q90695741A microtubule RELION-based pipeline for cryo-EM image processing
Q34281123A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
Q46576648A structural model for microtubule minus-end recognition and protection by CAMSAP proteins
Q46692048Analysis of the binding mode of laulimalide to microtubules: Establishing a laulimalide-tubulin pharmacophore
Q30843322Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes.
Q38719117Challenges and opportunities in the high-resolution cryo-EM visualization of microtubules and their binding partners
Q56232617Clinical and Functional Characterization of the Recurrent TUBA1A p.(Arg2His) Mutation
Q27671021Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy.
Q38631883Control of microtubule organization and dynamics: two ends in the limelight
Q41601854Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies
Q27670721Design and Characterization of Modular Scaffolds for Tubulin Assembly
Q35656185Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells
Q35579815Differential interactions of the formins INF2, mDia1, and mDia2 with microtubules
Q33843299Distinct Features of Doublecortin as a Marker of Neuronal Migration and Its Implications in Cancer Cell Mobility
Q37255696Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice
Q29394565Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends
Q28115161Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor
Q38396303Dynamic instability 30 years later: complexities in microtubule growth and catastrophe
Q33899183Dynamic microtubule association of Doublecortin X (DCX) is regulated by its C-terminus.
Q27678506EBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule Ends
Q48180791Elucidating the mechanism of action of the clinically approved taxanes: a comprehensive comparison of local and allosteric effects
Q36686747Expanding the spectrum of TUBA1A-related cortical dysgenesis to Polymicrogyria
Q27005889Extracellular and Intracellular Signaling for Neuronal Polarity
Q48183454Four-stranded mini microtubules formed by Prosthecobacter BtubAB show dynamic instability
Q92934482Further Insight into the Interactions of the Cytotoxic Macrolides Laulimalide and Peloruside A with Their Common Binding Site
Q38166377LIS1 and DCX: Implications for Brain Development and Human Disease in Relation to Microtubules.
Q37686831Loss of a doublecortin (DCX)-domain protein causes structural defects in a tubulin-based organelle of Toxoplasma gondii and impairs host-cell invasion
Q36235535Low-dose laulimalide represents a novel molecular probe for investigating microtubule organization
Q38116595MAPping out distribution routes for kinesin couriers
Q33786408Mechanism of microtubule stabilization by taccalonolide AJ.
Q88414640Microtubule dynamics: an interplay of biochemistry and mechanics
Q57470884Microtubule structure by cryo-EM: snapshots of dynamic instability
Q36543737Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites.
Q27671083Molecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family Proteins
Q27324158Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase
Q27683695Molecular mechanism of action of microtubule-stabilizing anticancer agents
Q36581137New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum
Q38741576Non-equilibrium assembly of microtubules: from molecules to autonomous chemical robots
Q34983970Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice
Q35000461Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations.
Q35679363Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes.
Q28081516Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment
Q64931077Separating the effects of nucleotide and EB binding on microtubule structure.
Q27689025Structural basis of microtubule stabilization by laulimalide and peloruside A
Q43200940Structural insight into TPX2-stimulated microtubule assembly.
Q83229454Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends
Q38017496Structural studies of ciliary components
Q37339521Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
Q30368446The Unique Binding Mode of Laulimalide to Two Tubulin Protofilaments.
Q34483807The contribution of αβ-tubulin curvature to microtubule dynamics.
Q30533916The doublecortin-related gene zyg-8 is a microtubule organizer in Caenorhabditis elegans neurons
Q61771642The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability
Q90416862Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies
Q36805556Visualizing microtubule structural transitions and interactions with associated proteins
Q27005924Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads

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