scholarly article | Q13442814 |
P50 | author | Pietro Roversi | Q28039121 |
Oscar Llorca | Q39715512 | ||
Susan M. Lea | Q42425353 | ||
Federico Forneris | Q55457275 | ||
Piet Gros | Q88960310 | ||
P2093 | author name string | Doryen Bubeck | |
Michael K Pangburn | |||
B Paul Morgan | |||
Svetlana Hakobyan | |||
Michael A Hadders | |||
P2860 | cites work | Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential | Q24315542 |
A common fold mediates vertebrate defense and bacterial attack | Q27647495 | ||
Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense | Q27648205 | ||
Structure of and influence of a tick complement inhibitor on human complement component 5 | Q27650767 | ||
The structural basis for membrane binding and pore formation by lymphocyte perforin | Q27665482 | ||
Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement | Q27667378 | ||
Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC) | Q27676846 | ||
Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form | Q27738974 | ||
XDS | Q27860472 | ||
Coot: model-building tools for molecular graphics | Q27860505 | ||
Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT | Q27860590 | ||
UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
Phasercrystallographic software | Q27860930 | ||
EMAN2: an extensible image processing suite for electron microscopy | Q27861052 | ||
The CCP4 suite: programs for protein crystallography | Q27861090 | ||
Structure of C3b reveals conformational changes that underlie complement activity | Q28269312 | ||
Structures of complement component C3 provide insights into the function and evolution of immunity | Q28273530 | ||
Evidence that C5b recognizes and mediates C8 incorporation into the cytolytic complex of complement | Q28301977 | ||
Molecular organization of C9 within the membrane attack complex of complement. Induction of circular C9 polymerization by the C5b-8 assembly | Q28610976 | ||
Bsoft: image processing and molecular modeling for electron microscopy | Q29614289 | ||
Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit | Q30157689 | ||
Image processing for electron microscopy single-particle analysis using XMIPP. | Q33341061 | ||
Regulation of the complement membrane attack pathway | Q33697279 | ||
Joint X-ray and neutron refinement with phenix.refine | Q34257680 | ||
Evidence for presence of an internal thiolester bond in third component of human complement. | Q36409419 | ||
The membrane attack complex of complement: relation of C7 to the metastable membrane binding site of the intermediate complex C5b-7. | Q36495504 | ||
Complement in human diseases: Lessons from complement deficiencies | Q37501005 | ||
Proteolytic transformation of SC5b-9 into an amphiphilic macromolecule resembling the C5b-9 membrane attack complex of complement | Q39694126 | ||
Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain | Q40290270 | ||
The membrane attack complex of complement. Assembly, structure and cytotoxic activity | Q40741469 | ||
Function of the factor I modules (FIMS) of human complement component C6. | Q41699451 | ||
Evidence of direct insertion of terminal complement proteins into cell membrane bilayers during cytolysis. Labeling by a photosensitive membrane probe reveals a major role for the eighth and ninth components | Q42259068 | ||
The reaction mechanism of human C5 in immune hemolysis | Q42835268 | ||
Monoclonal antibodies recognizing a neoantigen of poly(C9) detect the human terminal complement complex in tissue and plasma | Q43762567 | ||
SC5b-7, SC5b-8 and SC5b-9 complexes of complement: ultrastructure and localization of the S-protein (vitronectin) within the macromolecules | Q50335849 | ||
The membrane attack complex of complement: C5b-8 complex as accelerator of C9 polymerization. | Q54458101 | ||
Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5. | Q54499187 | ||
The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin | Q56917809 | ||
Functional Studies of the MACPF Domain of Human Complement Protein C8α Reveal Sites for Simultaneous Binding of C8β, C8γ, and C9† | Q57837353 | ||
Biochemical characterization of the sixth component (C6) of human complement | Q70331443 | ||
Ultrastructure of the membrane attack complex of complement. Heterogeneity of the complex caused by different degree of C9 polymerization | Q71394036 | ||
SC5b-9 complex of complement: formation of the dimeric membrane attack complex by removal of S-protein | Q72130336 | ||
Functional role of the noncatalytic subunit of complement C5 convertase | Q73368160 | ||
P433 | issue | 3 | |
P921 | main subject | Complement C5 | Q426181 |
Complement C6 | Q5156406 | ||
Complement C9 | Q21102471 | ||
Complement C8 alpha chain | Q21102473 | ||
Complement C8 beta chain | Q21102474 | ||
Complement C7 | Q21102480 | ||
P304 | page(s) | 200-207 | |
P577 | publication date | 2012-02-23 | |
P1433 | published in | Cell Reports | Q5058165 |
P1476 | title | Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9. | |
P478 | volume | 1 |
Q59800432 | A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Terminal Domain of the Staphylococcus aureus SSL7 Protein |
Q35002974 | A revised mechanism for the activation of complement C3 to C3b: a molecular explanation of a disease-associated polymorphism |
Q31154707 | AAV-mediated expression of human PRELP inhibits complement activation, choroidal neovascularization and deposition of membrane attack complex in mice |
Q57751835 | Advances in cryoEM and its impact on β-pore forming proteins |
Q58725179 | Advances in structure determination by cryo-EM to unravel membrane-spanning pore formation |
Q50061912 | Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-Containing Adhesins of the TRAP Family. |
Q38234314 | Bacteria under stress by complement and coagulation. |
Q64245049 | Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases |
Q37496310 | Bioinformatic analysis of the membrane cofactor protein CD46 and microRNA expression in hepatocellular carcinoma |
Q98187260 | C-Mannosylation Enhances the Structural Stability of Human RNase 2 |
Q51259647 | Chimeric approach for narrowing a membrane-inserting region within human perforin. |
Q55031290 | Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy. |
Q34481071 | Complement System Part I - Molecular Mechanisms of Activation and Regulation |
Q36380682 | Complement activation, regulation, and molecular basis for complement-related diseases |
Q90475736 | Complement membrane attack complex: new roles, mechanisms of action, and therapeutic targets |
Q33828385 | Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells |
Q27313232 | Conformational changes during pore formation by the perforin-related protein pleurotolysin |
Q40819035 | Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif |
Q60044764 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers |
Q42016535 | CspA from Borrelia burgdorferi inhibits the terminal complement pathway |
Q39479462 | Development of the Cellular Immune System of Drosophila Requires the Membrane Attack Complex/Perforin-Like Protein Torso-Like |
Q47976585 | Distinct localization of the complement C5b-9 complex on Gram-positive bacteria |
Q34300045 | Effects of MACPF/CDC proteins on lipid membranes. |
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Q35199125 | Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis |
Q38624669 | How novel structures inform understanding of complement function |
Q98465707 | Immune Evasion Strategies of Relapsing Fever Spirochetes |
Q54238314 | Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses. |
Q40223553 | Incomplete pneumolysin oligomers form membrane pores. |
Q38816011 | Innate Immune System at the Maternal-Fetal Interface: Mechanisms of Disease and Targets of Therapy in Pregnancy Syndromes |
Q40672986 | Invasive meningococcal disease in three siblings with hereditary deficiency of the 8(th) component of complement: evidence for the importance of an early diagnosis |
Q28066477 | Killing of Microbes and Cancer by the Immune System with Three Mammalian Pore-Forming Killer Proteins |
Q40654455 | Novel biomarker and easy to perform ELISA for monitoring complement inhibition in patients with atypical hemolytic uremic syndrome treated with eculizumab. |
Q36059050 | Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins |
Q38871927 | Pathogenic Leptospira Secreted Proteases Target the Membrane Attack Complex: A Potential Role for Thermolysin in Complement Inhibition. |
Q37535268 | Polyphosphate suppresses complement via the terminal pathway |
Q36479278 | Progress and Trends in Complement Therapeutics |
Q92807181 | Protosappanin-A and oleanolic acid protect injured podocytes from apoptosis through inhibition of AKT-mTOR signaling |
Q35774133 | Pseudomonas aeruginosa Uses Dihydrolipoamide Dehydrogenase (Lpd) to Bind to the Human Terminal Pathway Regulators Vitronectin and Clusterin to Inhibit Terminal Pathway Complement Attack |
Q26828812 | Putting the structure into complement |
Q36906411 | Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode. |
Q35657115 | Role of complement and complement regulatory proteins in the complications of diabetes |
Q64065747 | Single-molecule kinetics of pore assembly by the membrane attack complex |
Q36300934 | Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria |
Q34552556 | Streptococcus pneumoniae phosphoglycerate kinase is a novel complement inhibitor affecting the membrane attack complex formation |
Q27678091 | Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59 |
Q27333931 | Structural basis of complement membrane attack complex formation. |
Q38991069 | Structural insight into proteolytic activation and regulation of the complement system |
Q28115911 | Structure of the poly-C9 component of the complement membrane attack complex |
Q38991062 | Terminal complexes of the complement system: new structural insights and their relevance to function. |
Q30152922 | The Apicomplexan CDC/MACPF-like pore-forming proteins |
Q57651515 | The first transmembrane region of complement component-9 acts as a brake on its self-assembly |
Q39384364 | The mystery behind membrane insertion: a review of the complement membrane attack complex |
Q90374972 | The rational design of affinity-attenuated OmCI for the purification of complement C5 |
Q36643354 | The relative merits of therapies being developed to tackle inappropriate ('self'-directed) complement activation |
Q39217886 | The structure and function of thioester-containing proteins in arthropods |
Q43742728 | ¹H, ¹³C and ¹⁵N resonance assignments of the complement control protein modules of the complement component C7. |
Q107514917 | C5b6 complement complex | described by source | P1343 |
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